公开(公告)号：DE3269843D1

公开(公告)日：1986-04-17

申请号：DE3269843

申请日：1982-09-18

Applicant: BASF AG

Inventor： AQUILA WERNER DR ,  NISSEN AXEL DR ,  KAIBEL GERD ,  HORNER MICHAEL DR ,  REBAFKA WALTER DR

IPC: A61K8/33 ,  A61Q13/00 ,  B01D3/34 ,  B01D3/38 ,  C07B31/00 ,  C07B63/00 ,  C07C27/00 ,  C07C29/141 ,  C07C29/80 ,  C07C31/04 ,  C07C33/025 ,  C07C45/00 ,  C07C45/82 ,  C07C47/21 ,  C07C67/00 ,  C11B9/00 ,  C11B9/02

Abstract: Distillative separation of liquid mixtures of one or more water-insoluble substances which have boiling points higher than that of water and one or more substances which have boiling points lower than that of water or which form azeotropes having boiling points lower than that of water, wherein the mixture to be distilled is mixed with a quantity of water such that the boiling point of the water under the pressure applied limits the bottom temperature of the mixture of substances to be separated.

公开(公告)号：DE3160510D1

公开(公告)日：1983-08-04

申请号：DE3160510

申请日：1981-03-10

Applicant: BASF AG

Inventor： NISSEN AXEL DR ,  HORNER MICHAEL DR ,  HORN DIETER DR ,  LUEDDECKE ERIK DR ,  TEEGE GERNOT DR

IPC: C07D311/72 ,  C07D311/20 ,  C07D311/58 ,  C07D311/66 ,  C07D311/70 ,  C08K5/15 ,  C09K15/08 ,  C09K15/14 ,  C09K15/24 ,  C09K15/28

Abstract: Chroman derivatives of the general formula I I where R1, R2, R3 and R4 are each H or C1-C4-alkyl, R5 is C10-C30-alkyl or C10-C30-alkenyl, X and Y are each O, NH or S, m is 0, 1, 2 or 3 and n and r are each 0 or 1, the preparation of compounds I by various methods known per se, and the use of the compounds as stabilizers for organic materials.

公开(公告)号：CH634287A5

公开(公告)日：1983-01-31

申请号：CH1408177

申请日：1977-11-17

Applicant: BASF AG

Inventor： PASEDACH HEINRICH DR ,  MOHR RUDOLF DR ,  NISSEN AXEL DR

IPC: C07C45/00 ,  B01J31/00 ,  C07B61/00 ,  C07C45/67 ,  C07C49/203 ,  C07C67/00 ,  C07C45/54

公开(公告)号：DE3061786D1

公开(公告)日：1983-03-03

申请号：DE3061786

申请日：1980-08-14

Applicant: BASF AG

Inventor： HORNER MICHAEL DR ,  IRGANG MATTHIAS DR ,  NISSEN AXEL DR

IPC: C07C29/136 ,  B01J23/00 ,  B01J23/40 ,  B01J31/00 ,  B01J31/02 ,  C07B31/00 ,  C07B41/02 ,  C07B61/00 ,  C07C27/00 ,  C07C29/14 ,  C07C29/141 ,  C07C29/145 ,  C07C33/02 ,  C07C33/025 ,  C07C33/03 ,  C07C33/30 ,  C07C67/00

Abstract: Olefinically unsaturated alcohols (I) are prepared by selective hydrogenation of the corresponding carbonyl compounds (II) in the liquid phase with hydrogen, using an Ru, Rh, Os, Ir or Pt catalyst and carrying out the hydrogenation in the presence of from 5 to 40% by weight, based on (II), of a tertiary amine. The process is of particular importance for the selective hydrogenation of alpha , beta -unsaturated carbonyl compounds (IIa) and amongst these specifically for the hydrogenation of citral to geraniol and nerol. The preferred amine is trimethylamine.

公开(公告)号：DE3061510D1

公开(公告)日：1983-02-03

申请号：DE3061510

申请日：1980-08-14

Applicant: BASF AG

Inventor： HORNER MICHAEL DR ,  IRGANG MATTHIAS DR ,  NISSEN AXEL DR

IPC: C07C47/21 ,  B01J23/00 ,  B01J23/40 ,  B01J31/02 ,  B01J31/28 ,  C07B61/00 ,  C07C27/00 ,  C07C27/04 ,  C07C29/136 ,  C07C29/145 ,  C07C29/17 ,  C07C33/02 ,  C07C33/025 ,  C07C45/00 ,  C07C45/62 ,  C07C49/203 ,  C07C67/00

Abstract: Olefinically unsaturated carbonyl compounds R1-CHR2-CHR3-C(R4)O (I) and alcohols R1-CHR2-CHR3-CH(R4)-OH (II) (where R1 is an olefinically unsaturated organic radical, and R2, R3 and R4 are H or C1-C4-alkyl) are prepared by hydrogenating the carbonyl compounds R1-CR2=CR3-C(R4)O (III) in the liquid phase with hydrogen, using a catalyst system comprising, firstly, Pd and, secondly, Ru, Rh, Os, Ir or Pt, in the presence of from 5 to 40% by weight, based on (III), of a tertiary amine, under a hydrogen pressure of from 1 to 20 bar is predominantly (I) is to be obtained and from 20 to 150 bar if predominantly (II) is to be obtained. The process is of particular importance for the hydrogenation of citral (IIIa) to give citronellal (Ia) or citronellol (IIa), the preferred amine being trimethylamine.

公开(公告)号：DE2961383D1

公开(公告)日：1982-01-28

申请号：DE2961383

申请日：1979-01-31

Applicant: BASF AG

Inventor： OPGENORTH HANS-JOACHIM DR ,  SCHEUERMANN HORST DR ,  LAAS HARALD DR ,  NISSEN AXEL DR

IPC: C07D209/08

公开(公告)号：DE2652863B1

公开(公告)日：1978-05-18

申请号：DE2652863

申请日：1976-11-20

Applicant: BASF AG

Inventor： PASEDACH HEINRICH DR ,  MOHR RUDOLF DR ,  NISSEN AXEL DR

IPC: C07C45/67 ,  C07C49/20

公开(公告)号：DE2625540A1

公开(公告)日：1977-12-22

申请号：DE2625540

申请日：1976-06-05

Applicant: BASF AG

Inventor： NISSEN AXEL DR ,  HEILEN GERD DR ,  WOERZ GERD DR ,  FLIEGE WERNER DR ,  WITTWER ARNOLD DR

IPC: B01J23/63 ,  B01J23/83 ,  C07C45/73 ,  C07C45/74 ,  C07C49/06 ,  C07C45/00 ,  C07C49/20

Abstract: A process for the prepn. of higher ketones of formula: R'CH2CH2COR2 comprises the reaction of an aldehyde of formula (I): R1-CHO with ketones of formula (II) CH3COR2 at 80-280 degrees C in the presence of hydrogen and a catalytic system, which contains an oxide or salt of a rare earth metal or mixts. of these and one or more Group VIII metals. In the above, R' is 1-20C alkyl, esp. 1-5C), aryl or cycloalkyl opt. substd. by alkyl, or 7-20C (pref. 7-10 C) aralkyl; the above gps. may also be substd. by OH or alkoxyl gps. inert to the reaction conditions; R2 is the same as R'. Typical cpds. are methyl isoamyl ketone used as a solvent and intermediate and 4-phenyl-butan-2-one used in perfumery. As a result of the catalyst which favours both the condensation and hydrogenation steps, the process is more selective, simpler, cheaper and gives higher yields compared with previous processes. Using acetone and methyl propanol, the catalyst is 10% Ni, 10% Co, 10% rare earth oxides (95% Nd2O3) on an alumina support giving a mixture contg. 40.8% starting materials and 34.3% 5-methylhexane-2-one. The pref. reaction temp. is 140-220 degrees C.

公开(公告)号：DE3164366D1

公开(公告)日：1984-08-02

申请号：DE3164366

申请日：1981-03-09

Applicant: BASF AG

Inventor： HORNER MICHAEL DR ,  NISSEN AXEL DR

IPC: C07C69/73 ,  C07C51/00 ,  C07C51/353 ,  C07C59/52 ,  C07C59/58 ,  C07C59/64 ,  C07C67/00 ,  C07C67/343 ,  C07C69/732 ,  C07C69/734 ,  C08K5/10 ,  C08K5/13

Abstract: 4-(2,5-Dihydroxyphen-1-yl)-crotonic acid and its derivative (I) I where R1, R2, R3 and R4 are each H or C1-C8-alkyl, R5 is H, C1-C30-alkyl or C2-C30-alkenyl, and R' is H or an organic radical which can be split off hydrogenolytically, and a process for the preparation of the compounds I, wherein a hydroquinone II II is reacted, in the presence of from 0.1 to 2 moles of a Lewis acid per mole of II, with (a) a vinylglycolic acid derivative IIIa IIIa or (b) a crotonic acid derivative IIIb IIIb where X is halogen, hydroxyl or C1-C4-alkoxy or acyloxy.

公开(公告)号：DE3063676D1

公开(公告)日：1983-07-14

申请号：DE3063676

申请日：1980-07-01

Applicant: BASF AG

Inventor： NISSEN AXEL DR ,  KAIBEL GERD ,  WOERZ OTTO ,  ARNOLD LOTHAR DR ,  BRAUN MANFRED ,  REBAFKA WALTER DR

IPC: C07C49/20 ,  B01J31/14 ,  C07C45/00 ,  C07C45/67 ,  C07C45/68 ,  C07C49/203 ,  C07C67/00

Abstract: An improved process for the preparation of higher unsaturated ketones, such as geranylacetone and farnesylacetone, by reacting a beta , gamma -unsaturated alcohol and an alkyl acetoacetate at an elevated temperature in the presence of an organic aluminum compound, with elimination, and removal, of the alcohol derived from the alkyl acetoacetate in a reactor system carrying a fractionating column. The improvement in the purity, yield, and especially space-time yield of the product is achieved by starting from an alcohol having a higher boiling point than that of the alkyl acetoacetate used, carrying out the reaction in the presence of a small amount of an inert liquid which has a boiling point between that of the alkyl acetoacetate and the alcohol to be eliminated therefrom, and ensuring that the temperature at the bottom of the fractionating column is only slightly higher than the boiling point of the added liquid, under the prevailing pressure.