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公开(公告)号:WO9959541A2
公开(公告)日:1999-11-25
申请号:PCT/EP9903002
申请日:1999-05-04
Applicant: BASF AG , HEGER ROBERT , AUWETER HELMUT , PFLUEGER PETER , BREITENBACH JOERG , BINDER RUDOLF , ZEIDLER JUERGEN , BERNDL GUNTHER
Inventor: HEGER ROBERT , AUWETER HELMUT , PFLUEGER PETER , BREITENBACH JOERG , BINDER RUDOLF , ZEIDLER JUERGEN , BERNDL GUNTHER
CPC classification number: A61K9/5123 , A61K9/0095 , A61K9/1617 , A61K9/1658 , A61K9/5169 , A61K38/13
Abstract: The invention relates to solid or liquid cyclosporin preparations for oral administration in which the cyclosporin is presented in the form of solid X-amorphous particles embedded in a coating matrix in a colloidally dispersed manner.
Abstract translation: 存在嵌入在涂层基质的固体或液体环孢菌素制剂用于口服给药的,其中以固体,X射线无定形的颗粒形式的环孢菌素kolloidaldispers。
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公开(公告)号:CA2625861A1
公开(公告)日:2007-05-03
申请号:CA2625861
申请日:2006-10-17
Applicant: BASF AG
Inventor: SCHAEFER ANSGAR , BLANZ BIRGIT , GOEDEL WERNER A , MARTIN INGRID , KOLTENBURG SEBASTIAN , AUWETER HELMUT , PFLUEGER PETER
IPC: A01N25/04 , A01N25/28 , A01N43/40 , A01N43/653 , A01N47/24 , A01N47/34 , A01N53/00 , A01P3/00 , A01P7/00 , A01P13/00
Abstract: The present invention relates to aqueous dispersions comprising a nanoparticulate formulation of crop protection agents in which the nanoparticles have core-shell structures having a mean particle diameter of 0.05 to 2.0 mum and the crop protection agent is present in the core X-ray amorphous together with one or more polymers and the shell consists of a stabilizing coating matrix, preparable by a process which comprises (a) preparing a solution of the crop protection agent in a water-miscible organic solvent, (b) mixing the solution obtained in step (a) with the core polymer or a solution of the core polymer in a water-miscible organic solvent, where the polymer is not or only partially soluble in water or aqueous solutions or water/solvent mixtures, and (c) bringing the mixture resulting from (b) into contact with an aqueous solution comprising components of the coating matrix.
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公开(公告)号:NO20005769L
公开(公告)日:2000-11-14
申请号:NO20005769
申请日:2000-11-14
Applicant: BASF AG
Inventor: HEGER ROBERT , AUWETER HELMUT , PFLUEGER PETER , BREITENBACH JOERG , BINDER RUDOLF , ZEIDLER JUERGEN , BERNDL GUNTHER
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公开(公告)号:NO20005769D0
公开(公告)日:2000-11-14
申请号:NO20005769
申请日:2000-11-14
Applicant: BASF AG
Inventor: HEGER ROBERT , AUWETER HELMUT , PFLUEGER PETER , BREITENBACH JOERG , BINDER RUDOLF , ZEIDLER JUERGEN , BERNDL GUNTHER
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公开(公告)号:NO20005769A
公开(公告)日:2000-11-14
申请号:NO20005769
申请日:2000-11-14
Applicant: BASF AG
Inventor: HEGER ROBERT , AUWETER HELMUT , PFLUEGER PETER , BREITENBACH JOERG , BINDER RUDOLF , ZEIDLER JUERGEN , BERNDL GUNTHER
CPC classification number: A61K9/5123 , A61K9/0095 , A61K9/1617 , A61K9/1658 , A61K9/5169 , A61K38/13
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公开(公告)号:DE19821951A1
公开(公告)日:1999-11-18
申请号:DE19821951
申请日:1998-05-15
Applicant: BASF AG
Inventor: HEGER ROBERT , AUWETER HELMUT , PFLUEGER PETER , BREITENBACH JOERG , BINDER RUDOLF , ZEIDLER JUERGEN , BERNDL GUNTHER
Abstract: Orally administered solid or liquid cyclosporin compositions comprise cyclosporin in the form of solid, X-ray amorphous particles colloidally dispersed in a matrix. Orally administered solid or liquid cyclosporin compositions are claimed, which comprise cyclosporin in the form of solid, X-ray amorphous particles colloidally dispersed in a matrix. An Independent claim is also included for preparation of the compositions.
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