公开(公告)号：JP2002255931A

公开(公告)日：2002-09-11

申请号：JP2001361568

申请日：2001-11-27

Applicant: BASF AG

Inventor： AUWETER HELMUT ,  BOHN HERIBERT ,  LUDDECKE ERIK ,  HINZ WILLY ,  RUNGE FRANK ,  PFEIFFER ANGELIKA-MARIA

IPC: B01J2/08 ,  A23K1/00 ,  A23K1/16 ,  A23K1/20 ,  A23L1/00 ,  A23L1/275 ,  A23L5/40 ,  A23L33/155 ,  A23P1/06 ,  A61K8/04 ,  A61K8/11 ,  A61K8/30 ,  A61K8/31 ,  A61K8/34 ,  A61K8/35 ,  A61K9/14 ,  A61K9/16 ,  A61K9/50 ,  A61K9/51 ,  A61K31/01 ,  A61K31/015 ,  A61K31/045 ,  A61K31/522 ,  A61Q1/12 ,  C07C11/21 ,  C07C403/24 ,  A23L1/27 ,  A61K7/00

Abstract: PROBLEM TO BE SOLVED: To provide a method for producing a solid preparation of a water-soluble, a slightly water-soluble or a water-insoluble active compound. SOLUTION: This method for producing the solid preparation which is made of at least one kind of the water-soluble, the slightly water-soluble, and the water-insoluble active compound and suitably used for fields of food and animal feeding stuff or medicaments and cosmetics comprises (a) a process where at least one kind among the above active compounds is dissolved or dispersed in an aqueous molecular dispersion or an aqueous colloidal dispersion of a proteinaceous protective colloid, (b) another process where the proteinaceous protective colloid is aggregated and deposited from the dispersion together with the active compound, and (c) the other process where the aggregated solid is separated from water and an arbitrary solvent which is additionally used, and then the solid is converted into a dry powder.

公开(公告)号：JP2002204673A

公开(公告)日：2002-07-23

申请号：JP2001256256

申请日：2001-08-27

Applicant: BASF AG

Inventor： AUWETER HELMUT ,  JENSEN NINA MUSAEUS ,  LUEDDECKE ERIK ,  RUNGE FRANK

IPC: A23K20/158 ,  A23K20/174 ,  A23K20/179 ,  A23L5/44 ,  A23L33/155 ,  A23P1/00 ,  A61J3/07 ,  A61K8/00 ,  A61K8/11 ,  A61K8/31 ,  A61K8/34 ,  A61K9/14 ,  A61K9/16 ,  A61K9/20 ,  A61K9/48 ,  A61K9/51 ,  A61K31/015 ,  A61Q19/00 ,  A61Q90/00 ,  B01J19/00 ,  A23L1/302 ,  A23K1/16 ,  A23K1/20 ,  A23L1/00 ,  A23L1/30 ,  A61K7/00

Abstract: PROBLEM TO BE SOLVED: To provide a solid preparation comprising active ingredients where, in addition to its safety, homogeneous and uniform distribution of active compounds is made ensured in all particles of the preparation. SOLUTION: This solid preparation having a multicore structure comprises at least two kinds of active compounds suitable for utilizing in the fields of food, feed, medicine, or cosmetics, wherein at least two cores in the multicore structure have different chemical compositions from each other.

公开(公告)号：JP2002262824A

公开(公告)日：2002-09-17

申请号：JP2001383736

申请日：2001-12-17

Applicant: BASF AG

Inventor： RUNGE FRANK ,  LUEDDECKE ERIK ,  AUWETER HELMUT ,  PFEIFFER ANGELIKA-MARIA ,  HINZ WILLY

IPC: A23K1/16 ,  A23J3/16 ,  A23L33/155 ,  A61K9/14 ,  A61K9/16 ,  A61K9/64 ,  A61K31/047 ,  A61K31/07 ,  A61K31/11 ,  A61K31/122 ,  A61K31/215 ,  A61K31/235 ,  A61P3/02 ,  A23L1/272 ,  A23L1/00

Abstract: PROBLEM TO BE SOLVED: To provide a method for producing dried powder oxygen-containing carotenoids, by using a protective colloid not exhibiting disadvantages of conventional technique. SOLUTION: This method for producing dried powder of one or several oxygen-containing carotenoids comprises (a) dispersing one or several kinds of oxygen-containing carotenoids into an aqueous molecular dispersion or a colloidal dispersion of protective colloid and (b) removing water and another solvent used, drying the oxygen-containing carotenoids in the presence or absence of a coating agent to convert the formed dispersion into the dried powder. In the method, at least one kind of a partially hydrolyzed soybean protein having a rate of hydrolysis larger than 5% is used as the protective colloid in the step (a).

公开(公告)号：JP2001271054A

公开(公告)日：2001-10-02

申请号：JP2001039162

申请日：2001-02-15

Applicant: BASF AG

Inventor： HEGER ROBERT ,  AUWETER HELMUT ,  DAUSCH WILMA M ,  ZWISSLER GEORG KONRAD ,  WUENSCH THOMAS

IPC: A61K9/08 ,  A61K8/00 ,  A61K8/04 ,  A61K8/49 ,  A61K31/4192 ,  A61K31/53 ,  A61K45/00 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q1/12 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/00 ,  C09K3/00 ,  A61K7/00 ,  A61K7/42 ,  A61K7/48

Abstract: PROBLEM TO BE SOLVED: To provide a product of an ultraviolet-protecting agent having effective action for protecting an organic material, especially the skin and/or the hair of a human from ultraviolet rays, and capable of being compounded readily in an aqueous system or a lipophilic system. SOLUTION: An aqueous dispersion of a scarcely water-soluble or water- insoluble organic UV-filter material containing at least one kind of scarcely water-soluble or water-insoluble organic UV-filter material as an amorphous or partially amorphous colloidal dispersion phase.

公开(公告)号：JPH10101954A

公开(公告)日：1998-04-21

申请号：JP24899697

申请日：1997-09-12

Applicant: BASF AG

Inventor： AUWETER HELMUT ,  BOHN HERIBERT ,  HABERKORN HERBERT ,  HORN DIETER ,  LUEDDECKE ERIK ,  RAUSCHENBERGER VOLKER

IPC: A23K1/16 ,  A23L1/275 ,  A23L5/44 ,  A61K9/16 ,  C07C403/24 ,  C09B61/00 ,  C09B67/06 ,  C09B67/10 ,  C09B67/46 ,  A23L1/272

Abstract: PROBLEM TO BE SOLVED: To provide a finely powdered carotenoid preparation controllable to have intended coloration effects and having a high bioavailability. SOLUTION: The production process comprises forming a molecular dispersion of carotenoid at an elevated temperature in a water-miscible volatile organic solvent optionally together with an emulsifier and/or an edible oil and adding a protective colloid to the solution. In this process, the hydrophilic solvent component is transferred to the water phase to form a hydrophobic phase of carotenoid as a nano-disperse phase and the obtained hydrosol is heat-treated at 40-90 deg.C. Then the solvent and water are removed from the heat-treated hydrosol to convert it into a water-dispersible dry powder.

公开(公告)号：WO2005009144A8

公开(公告)日：2005-06-16

申请号：PCT/EP0312557

申请日：2003-11-11

Applicant: BASF AG ,  AUWETER HELMUT ,  BOHN HERIBERT ,  HASSELWANDER OLIVER ,  RUNGE FRANK

Inventor： AUWETER HELMUT ,  BOHN HERIBERT ,  HASSELWANDER OLIVER ,  RUNGE FRANK

IPC: A23K1/00 ,  A23K1/16 ,  A23L1/30 ,  A61K8/02 ,  A61K8/63 ,  A61K31/575 ,  A61Q1/00 ,  A61Q19/00 ,  A23K1/165

CPC classification number: A61K8/02 ,  A23K20/158 ,  A23K20/174 ,  A23K40/10 ,  A23L33/11 ,  A23V2002/00 ,  A61K8/63 ,  A61K31/575 ,  A61Q1/00 ,  A61Q19/00 ,  A23V2250/2136 ,  A23V2250/5072 ,  A23V2250/54246 ,  A23V2250/5028

Abstract: The invention relates to pulverulent phytosterol formulations, methods for the production and use thereof. The aim of said invention is to deliver the phytosterol formulations incorporatable in aqueous and oily preparations. For this purpose, said pulverulent phytosterol formulations contain at least one type of phytosterol whose mean particle size ranges from 0.01 and 100 mu m, preferably from 0.01 to 10 mu m, better from 0.01 and 2 mu m and ideally from 0.05 and 1 mu m. Said phytosterol formulations are characterised, in particular in that at least one type of phytosterol is used in a semi-amorphous form. In a preferred embodiment, said phytosterol formulations are characterised in that said phytosterol is embedded in a protective colloid matrix.

Abstract translation: 本发明涉及一种粉状植物甾醇制剂，它们的制备方法和它们的用途。 这是本发明的一个目的是提供一种含有植物固醇制剂，其既可以在水性和油性制剂掺入。 根据本发明这个目的已经通过包括具有在0.01至100微米范围内的平均粒径的至少一种植物甾醇，优选在0.01至2微米的范围内，最优选在0.05〜1的范围微米粉末状植物甾醇制剂实现 ， 本发明的植物甾醇制剂包括 特征还在于，至少一种植物甾醇的存在部分无定形的形式。 植物甾醇制剂的另一优选实施例的特征在于，所述植物甾醇被嵌入在保护性胶体基质。

公开(公告)号：WO2005075385A3

公开(公告)日：2007-02-08

申请号：PCT/EP2005001016

申请日：2005-02-02

Applicant: BASF AG ,  FELDTHUSEN JENSEN JESPER ,  AUWETER HELMUT ,  HABICH ANDREAS ,  LUEDDECKE ERIK ,  PFEIFFER ANGELIKA-MARIA

Inventor： FELDTHUSEN JENSEN JESPER ,  AUWETER HELMUT ,  HABICH ANDREAS ,  LUEDDECKE ERIK ,  PFEIFFER ANGELIKA-MARIA

IPC: A23K1/16 ,  A23K1/00 ,  A23K1/18 ,  A23L1/275 ,  A23L1/303 ,  A61K31/015 ,  B01J13/20 ,  B65B9/04 ,  B65B31/02 ,  B65B65/02 ,  C07C20060101 ,  C07C403/24 ,  C09B61/00 ,  C09B67/00 ,  C09B67/04 ,  C09B67/08

CPC classification number: C09B67/0092 ,  A23K20/147 ,  A23K20/163 ,  A23K20/179 ,  A23K40/10 ,  A23K50/75 ,  A23K50/80 ,  A23L5/44 ,  A61K31/015 ,  C07C403/24 ,  C09B67/0002

Abstract: The invention relates to a method for producing dry powders of one or several carotenoids, said method being characterised in that a) one or several carotenoids are suspended in an aqueous molecularly dispersed or colloidally dispersed solution of a mixture consisting of trehalose and at least one protein-containing protective colloid and b) the obtained suspension is transformed into a dry powder by separation of water and, optionally, additionally used solvents and by subsequent drying, optionally in the presence of a coating material.

Abstract translation: 本发明涉及一种用于在海藻糖和至少一种的混合物的水性分子或胶体溶液生产一种或多种类胡萝卜素，其特征在于：a）一种或多种类胡萝卜素的干粉蛋白质保护胶体悬浮和b）通过分离形成的悬浮液 的水和任选另外地，如果合适的话，转换使用的溶剂和随后的干燥的涂层材料的存在成干粉。

公开(公告)号：WO2006045534A3

公开(公告)日：2006-08-10

申请号：PCT/EP2005011302

申请日：2005-10-20

Applicant: BASF AG ,  FREUDENBERG UWE ,  ZSCHOCHE STEFAN ,  WERNER CARSTEN ,  SCHMIDT KATI ,  BEHRENS SVEN HOLGER ,  AUWETER HELMUT

Inventor： FREUDENBERG UWE ,  ZSCHOCHE STEFAN ,  WERNER CARSTEN ,  SCHMIDT KATI ,  BEHRENS SVEN HOLGER ,  AUWETER HELMUT

IPC: C08B15/00

CPC classification number: C08G77/388 ,  B05D1/185 ,  B05D3/142 ,  B05D5/04 ,  B05D7/52 ,  D06M15/05 ,  D06M15/263 ,  D06M2200/00 ,  Y10T428/2938 ,  Y10T428/2998 ,  Y10T428/3179

Abstract: The invention relates to a method for producing multi-layered surface structures, particles or fibres. Said method comprises the following steps: the reactive polycarboxylic acid or a derivative thereof is applied to a flat, particle or fibre-shaped support material which already contains the groups which can react with polycarboxylic acid or a derivative thereof, in order to form a covalent connection or is initially provided with said groups; (b) the carrier material treated in step a is, optionally, heated to between 60 °C to 130 °C, preferably to 80 °C to 120 °C due to acceleration, completion or additional optimisation of the covalent connections; (c) cellulose is applied to the carrier material which can form a covalent connection with the polycarboxylic acid or the derivatives thereof. The invention also relates to the use of the inventive method for producing multi-layered surface structures, particles or fibres for hydrophilizing surfaces, in particular for promoting adhesion between hydrophobic and hydrophilic materials and to improve the washability of synthetic fibres. The surfaces which are hydrophilizied by said method form the flat, particle or fibre-shaped carrier material.

Abstract translation: 用于生产多层片状结构，粒子或纤维的方法，包括以下步骤：将反应性多元羧酸或它们的一种片状，颗粒状或纤维状载体材料衍生物已经包含相对于所述聚羧酸或能共价键合基团的它们的衍生物的反应基团 或提前提供; （b）任选地加热步骤a。 处理的载体材料至60℃〜130℃，优选在80℃至120℃下的加速，完成或进一步优化的共价键; （c）将能够共价键合的纤维素施加到载体材料上的多元羧酸或其衍生物。 此外，本发明涉及使用本发明方法的用于生产多层片状结构，粒子或纤维为亲水化的表面，特别是用于促进所述疏水性和亲水性材料之间以及提高合成纤维的可洗性粘附，其表面被处理亲水化 ，其形成平坦的，颗粒状或纤维状的载体材料。

公开(公告)号：WO2007036494A3

公开(公告)日：2007-05-18

申请号：PCT/EP2006066663

申请日：2006-09-25

Applicant: BASF AG ,  BRATZ MATTHIAS ,  AUWETER HELMUT

Inventor： BRATZ MATTHIAS ,  AUWETER HELMUT

IPC: A01N25/10 ,  A01N25/04 ,  A01P3/00 ,  A01P7/02 ,  A01P7/04 ,  A01P13/00 ,  A01P21/00

CPC classification number: A01N25/10 ,  A01N25/04 ,  A01N25/12

Abstract: The invention relates to agrochemical formulations comprising polymer particles that contain active substances. Said agrochemical formulations comprise a vinyl polymer which is composed of 10 to 80 percent by weight of monomers containing amino groups and/or carboxyl groups and is non-soluble in one portion of the 0 to 10 pH range while being soluble in another portion. The inventive agrochemical formulations are characterized in that the polymer particles containing active substances (i) comprise 3 to 1000 parts by weight of pesticide per weight ratio of vinyl polymer as an active substance; (ii) have a particle size ranging from 10nm to 100?m; (iii) > 50 percent by weight of the vinyl polymer is composed of polymers having a molecular weight

Abstract translation: 本发明涉及到按重量计的氨基和/或羧基的包含来自10 80％包含乙烯基聚合物的活性化合物fhaltige聚合物颗粒农业化学配制剂的0-10单体基团的是在pH范围的一个部分不溶性的和可溶于区域的另一部分 其特征在于所述含活性化合物的聚合物按重量计乙烯基聚合物粒子每部分F（1）为3〜1000重量份的农药作为活性成分的; （ii）颗粒大小在10纳米的范围内 - lOOμmaufweisen; （三）> 50 <100,000道尔顿的构造与乙烯基聚合物％（重量）的分子量的聚合物的; 且其中所述农药是存在于聚合物中分子分散溶解的形式; 和用于制备这些聚合物颗粒的过程，防治植物病原性真菌和/或不希望的植物生长和/或不希望的昆虫或螨虫侵染和/或用于调节使用上述颗粒的植物的生长的方法。

公开(公告)号：WO9959541A2

公开(公告)日：1999-11-25

申请号：PCT/EP9903002

申请日：1999-05-04

Applicant: BASF AG ,  HEGER ROBERT ,  AUWETER HELMUT ,  PFLUEGER PETER ,  BREITENBACH JOERG ,  BINDER RUDOLF ,  ZEIDLER JUERGEN ,  BERNDL GUNTHER

Inventor： HEGER ROBERT ,  AUWETER HELMUT ,  PFLUEGER PETER ,  BREITENBACH JOERG ,  BINDER RUDOLF ,  ZEIDLER JUERGEN ,  BERNDL GUNTHER

IPC: A61K9/16 ,  A61K9/51 ,  A61K38/00 ,  A61K38/13 ,  A61K47/14 ,  A61K47/36 ,  A61P37/06 ,  A61K9/00

CPC classification number: A61K9/5123 ,  A61K9/0095 ,  A61K9/1617 ,  A61K9/1658 ,  A61K9/5169 ,  A61K38/13

Abstract: The invention relates to solid or liquid cyclosporin preparations for oral administration in which the cyclosporin is presented in the form of solid X-amorphous particles embedded in a coating matrix in a colloidally dispersed manner.

Abstract translation: 存在嵌入在涂层基质的固体或液体环孢菌素制剂用于口服给药的，其中以固体，X射线无定形的颗粒形式的环孢菌素kolloidaldispers。