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公开(公告)号:CA1057894A
公开(公告)日:1979-07-03
申请号:CA233155
申请日:1975-08-08
Applicant: BASF AG
Inventor: HERRLE KARL , DENZINGER WALTER , SEELERT KURT
IPC: C08F2/00 , C08F2/04 , C08F4/00 , C08F4/40 , C08F26/00 , C08F26/10 , C08F126/10 , C08F126/08
Abstract: Polyvinylpyrrolidone is manufactured by polymerization of vinylpyrrolidone in an organic solvent in the presence of organic per-compounds wherein an anhydrous organic solvent is used and a heavy metal of atomic number from 23 to 29, in the form of a complex compound or a salt with an organic acid, is added as a co-activator. The polyvinylpyrrolidone manufactured according to the invention is used for pharmaceutical or cosmetic purposes, especially for the manufacture of polyvinylpyrrolidone-iodine.
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公开(公告)号:AU8374875A
公开(公告)日:1977-02-10
申请号:AU8374875
申请日:1975-08-07
Applicant: BASF AG
Inventor: HERRLE KARL , DENZINGER WALTER , SEELERT KURT , SCHWARZ WOLFGANG
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公开(公告)号:DK151814B
公开(公告)日:1988-01-04
申请号:DK369575
申请日:1975-08-15
Applicant: BASF AG
Inventor: HERRLE KARL , DENZINGER WALTER , SEELERT KURT , SCHWARZ WOLFGANG
IPC: A61K31/18 , A61K31/785 , A61K31/79 , A61K33/18 , C08F8/00 , C08F8/20 , C08F126/10 , C08F8/22
Abstract: Polyvinylpyrrolidone-iodine, manufactured by reaction of iodine and a polyvinylpyrrolidone obtained by polymerization in an anhydrous organic solvent in the presence of a source of free radicals and optionally in the presence of a heavy metal of atomic number from 23 to 29, in the form of a complex compound or of a salt with an organic acid, as a co-activator, followed by steam distillation of this polyvinylpyrrolidone, if appropriate. The PVP-iodine of the invention is very stable and can be used as a disinfectant.
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公开(公告)号:CA1081394A
公开(公告)日:1980-07-08
申请号:CA334554
申请日:1979-08-28
Applicant: BASF AG
Inventor: HERRLE KARL , DENZINGER WALTER , SEELERT KURT , SCHWARZ WOLFGANG
IPC: C08F126/08
Abstract: A process for the manufacture of polyvinylpyrrolidoneiodine from polyvinyl pyrrolidone and iodine which comprises: - the free radical polymerization of vinylpyrrolidone in a anhydrous organic solvent selected from the group consisting of aromatic hydrocarbons, lower aliphatic monohydric alcohols of 1 to 4 carbon atoms, in the presence of free radicals supplied by an organic per-compound in an amount of about 0.5 to 5% by weight on the basis of the weight of the vinylpyrrolidone; - converting the obtained polyvinylpyrrolidone, after completion of polymerization and before drying, into an aqueous solution by adding water and distilling off the organic solvent, the aqueous solution then being subjected to treatment with steam and reacting the aqueous polyvinylpyrrolidone solution with iodine.
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公开(公告)号:CA1079443A
公开(公告)日:1980-06-10
申请号:CA233153
申请日:1975-08-08
Applicant: BASF AG
Inventor: HERRLE KARL , DENZINGER WALTER , SEELERT KURT , SCHWARZ WOLFGANG
IPC: A61K31/18 , A61K31/785 , A61K31/79 , A61K33/18 , C08F8/00 , C08F8/20 , C08F126/10 , C08F8/22
Abstract: A process for the manufacture of polyvinylpyrrolidoneiodine from polyvinyl pyrrolidone and iodine which comprises: -the free radical polymerization of vinylpyrrolidone in a anhydrous organic solvent selected from the group consisting of aromatic hydrocarbons, lower aliphatic monohydric alcohols of 1 to 4 carbon atoms, in the presence of free radicals supplied by an organic per-compound in an amount of about 0.5 to 5% by weight on the basis of the weight of the vinylpyrrolidone; -mixing the resulting polyvinylpyrrolidone in the form of a powder having a K value of from 10 to 50 and a water content of from 0.5 to 11% by weight with iodine in an amount of about 5 to 25% based on the total weight of the polyvinylpyrrolidoneiodine, at about room temperature up to about 50.degree.C and, -heating the resulting mixture for about 5 to 20 hours at about 70 to 100.degree.C.
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公开(公告)号:DK151814C
公开(公告)日:1988-06-06
申请号:DK369575
申请日:1975-08-15
Applicant: BASF AG
Inventor: HERRLE KARL , DENZINGER WALTER , SEELERT KURT , SCHWARZ WOLFGANG
IPC: A61K31/18 , A61K31/785 , A61K31/79 , A61K33/18 , C08F8/00 , C08F8/20 , C08F126/10 , C08F8/22
Abstract: Polyvinylpyrrolidone-iodine, manufactured by reaction of iodine and a polyvinylpyrrolidone obtained by polymerization in an anhydrous organic solvent in the presence of a source of free radicals and optionally in the presence of a heavy metal of atomic number from 23 to 29, in the form of a complex compound or of a salt with an organic acid, as a co-activator, followed by steam distillation of this polyvinylpyrrolidone, if appropriate. The PVP-iodine of the invention is very stable and can be used as a disinfectant.
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公开(公告)号:HU171231B
公开(公告)日:1977-12-28
申请号:HUBA003309
申请日:1975-08-14
Applicant: BASF AG
Inventor: HERRLE KARL , SEELERT KURT , SCHWARZ WOLFGANG , DENZINGER WALTER
IPC: A61K31/18 , A61K31/785 , A61K31/79 , A61K33/18 , C08F8/00 , C08F8/20 , C08F126/10 , C08F8/22
Abstract: Polyvinylpyrrolidone-iodine, manufactured by reaction of iodine and a polyvinylpyrrolidone obtained by polymerization in an anhydrous organic solvent in the presence of a source of free radicals and optionally in the presence of a heavy metal of atomic number from 23 to 29, in the form of a complex compound or of a salt with an organic acid, as a co-activator, followed by steam distillation of this polyvinylpyrrolidone, if appropriate. The PVP-iodine of the invention is very stable and can be used as a disinfectant.
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公开(公告)号:FR1393060A
公开(公告)日:1965-03-19
申请号:FR974071
申请日:1964-05-11
Applicant: BASF AG
Inventor: DOERFEL HELMUT , METZGER HORST , RAFF PAUL , SEELERT KURT
IPC: C07D201/04
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