-
1.发明申请UTILIZATION OF VINYL ACETATE SULFONATE COPOLYMERS AS SOLUBILIZERS FOR COMPOUNDS WITH LOW SOLUBILITY IN WATER 审中-公开乙酸乙烯酯磺酸盐共聚物在水CONNECTIONS增溶剂难溶USE
公开(公告)号：WO2007141182A3
公开(公告)日：2008-05-08
申请号：PCT/EP2007055309
申请日：2007-05-31
Applicant: BASF SE , DOBRAWA RAINER , BOUILLO NATHALIE , LANGE RONALD FRANS MARIA , MEYER-BOEHM KATHRIN , MERTOGLU MURAT
Inventor： DOBRAWA RAINER , BOUILLO NATHALIE , LANGE RONALD FRANS MARIA , MEYER-BOEHM KATHRIN , MERTOGLU MURAT
IPC: A61K9/14 , A01N25/10 , A61K8/81 , A61K47/32 , C08F218/08
CPC classification number: A01N25/30 , A61K8/8147 , A61K8/8152 , A61K9/0014 , A61Q19/00 , C08F218/08 , C08F220/38 , C08F228/02
Abstract: The utilization of copolymers obtained by means of radically initiated copolymerization of a) 80 to 99,5% vinyl acetate by weight and b) 0,5 to 20% by weight of a sulfonate group-carrying, mono-olefinically unsaturated monomer, as solubilizers for substances with low solubility in water.
Abstract translation: 对于难溶于水的用途是：a）80至99.5重量％的乙酸乙烯酯的自由基引发的共聚反应获得，和b）从0.5至20重量的含磺酸酯基团的单烯非饱和单体的％增溶剂共聚物的 物质。
-
公开(公告)号：WO2010112489A3
公开(公告)日：2011-02-24
申请号：PCT/EP2010054167
申请日：2010-03-30
Applicant: BASF SE , MEYER-BOEHM KATHRIN , DOBRAWA RAINER , FISCHER STEFAN , KOLTER KARL
Inventor： MEYER-BOEHM KATHRIN , DOBRAWA RAINER , FISCHER STEFAN , KOLTER KARL
CPC classification number: A61K9/2095 , A23L5/40 , A23L33/00 , A23L33/10 , A23P10/30 , A61K8/86 , A61K8/91 , A61K9/146 , A61K9/1641 , A61K9/1682 , A61K9/1694 , A61K47/34 , A61Q19/00 , C08F18/08 , C08F226/06 , C08F226/10 , C08F283/06
Abstract: The invention relates to a method for producing preparations of substances poorly soluble in water, wherein the poorly soluble substances are present amorphously embedded in a copolymer, and the copolymer is obtained by radically initiated polymerization of a mixture of i) 30 to 80 wt% N-vinyl lactam, ii) 10 to 50 wt% vinyl acetate, and iii) 10 to 50 wt% of a polyether, with the stipulation that the sum of the components i), ii), and iii) is equal to 100 wt%, wherein the embedding of the poorly soluble substance into the copolymer occurs at temperatures above the melting point of the poorly soluble substances.
Abstract translation: 本发明涉及一种用于微溶于水的物质，其特征在于，存在于无定形的微溶物质包埋在共聚物制剂的制备，并且通过我的从30的混合物）的自由基引发的聚合反应，80重量％N获得的共聚物 乙烯基内酰胺，ⅱ）10〜50重量％的乙酸乙烯酯，和iii）10至50重量的聚醚，条件的％各组分i）的总和，ii）和iii）等于100重量％ ，其中在所述共聚物中的微溶物质的嵌入是在温度的微溶物质的熔点以上进行。
-
公开(公告)号：AU2017300595B2
公开(公告)日：2021-11-11
申请号：AU2017300595
申请日：2017-07-17
Applicant: BASF SE
Inventor： MEYER-BOEHM KATHRIN , HELGASON THRANDUR , SINGH RAAJVINDER , DOBLER WALTER , SCHORDING PETER , WIGBERS CHRISTOF WILHELM , KOLTER KARL , BRUHNS STEFAN , PELLETIER WOLF , WAGNER DANIEL
IPC: A23L33/15 , A23K20/174 , A23L33/155 , A23P10/20 , A61K8/31 , A61K31/07 , C07C403/24
Abstract: The present invention relates to a powdery vitamin preparation, in which the vitamin has substantially a particle size of less than 0.7 µm and which contains an effective amount of propyl gallate. The invention also relates to methods for the production of said preparation, to preparations that can be obtained according to said methods and to their use as animal feed, food, food supplements, body care products or pharmaceutical agents. The preparations according to the invention have a stability that is improved compared to the prior art.
-
公开(公告)号：ES2388470T3
公开(公告)日：2012-10-15
申请号：ES08858493
申请日：2008-12-10
Applicant: BASF SE
Inventor： KOLTER KARL , ANGEL MAXIMILIAN , MEYER-BOEHM KATHRIN
Abstract: Sales poliméricas solubles en agua de fármacos difícilmente solubles en agua, compuestas por un polímerosoluble en agua con carácter aniónico, presentando el polímero con carácter aniónico un porcentaje demonómeros que portan grupos carboxilo de al menos el 40% en peso y en una disolución acuosa al 1% enpeso un valor de K según Fikentscher inferior a 90 y ascendiendo la solubilidad en agua en el intervalo depH de desde 3 hasta 11 a más del 10% (m/m), y un fármaco difícilmente soluble en agua con caráctercatiónico, presentando el fármaco en su forma no cargada o como hidrocloruro una solubilidad inferior al 0,1% (m/m) en agua, jugo gástrico o jugo intestinal artificial.
-
5.发明申请USE OF POLYETHER-BASED AND VINYL MONOMER-BASED COPOLYMERS AS BINDERS FOR DOSING FORMS COMPRISING SOLID ACTIVE INGREDIENTS 审中-公开基于聚醚和乙烯基单体作为粘合剂FOR固体含活性剂型共聚物的用途
公开(公告)号：WO2010034688A3
公开(公告)日：2011-02-24
申请号：PCT/EP2009062199
申请日：2009-09-21
Applicant: BASF SE , MEYER-BOEHM KATHRIN , DOBRAWA RAINER , MASCHKE ANGELIKA , KOLTER KARL
Inventor： MEYER-BOEHM KATHRIN , DOBRAWA RAINER , MASCHKE ANGELIKA , KOLTER KARL
CPC classification number: A61K47/34 , A61K9/1641 , A61K9/2031 , A61K9/2095
Abstract: Use of water-soluble or water-dispersible copolymers obtained through radically-initiated polymerization of a mixture of i) 30 to 80 wt.-% of N-vinyl lactam, ii) 10 to 50 wt.-% of vinyl acetate and iii) 10 to 50 wt.-% of a polyether as a binder for the manufacture of dosing forms comprising solid active ingredients, said copolymers being conditioned in that the total of i), ii) and iii) is equal to 100 wt.-%.
Abstract translation: 其通过我的从30的混合物）的自由基引发的聚合至80重量％的N-乙烯基内酰胺得到的水溶性或水分散性共聚物，ⅱ）10至50重量％的乙酸乙烯酯，和iii）10至50重量％的使用 聚醚，条件是i的总和），ii）和iii）等于100重量％，作为固体含活性成分的剂型的制备的粘合剂。
-
Patent Agency Ranking6.发明申请PHARMACEUTICAL FORMULATION FOR THE PRODUCTION OF RAPIDLY DISINTEGRATING TABLETS 审中-公开药物制剂FOR FAST崩解片剂的制造
公开(公告)号：WO2008148733A3
公开(公告)日：2009-09-17
申请号：PCT/EP2008056765
申请日：2008-06-02
Applicant: BASF SE , KOLTER KARL , SCHOENHERR MICHAEL , GEBERT SILKE , MEYER-BOEHM KATHRIN , MASCHKE ANGELIKA
Inventor： KOLTER KARL , SCHOENHERR MICHAEL , GEBERT SILKE , MEYER-BOEHM KATHRIN , MASCHKE ANGELIKA
CPC classification number: A61K9/0056 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/2018 , A61K9/2027 , A61K9/2054
Abstract: The invention relates to a pharmaceutical formulation in the form of compacts containing a) 60 - 97 % by weight of sugar or sugar alcohols, b) 1 - 25 % by weight of a disintegration agent selected from the group consisting of croscarmellose, sodium carboxymethyl starch and L-hydroxypropyl cellulose, c) 1 - 15 % by weight of water insoluble film-forming polymers, d) 0 - 15 % by weight of water-soluble polymers, and e) 0 - 15 % by weight of additional conventional pharmaceutical adjuvants, the sum of the components a) to e) totalling 100 % by weight.
Abstract translation: 在含有糖或糖醇的）60-97重量％的聚集体形式的药物制剂，选自交联羧甲基的基团，羧甲基淀粉钠和L-羟丙基纤维素，C）1-15选择的B）1-25重量的崩解剂％ 重量％水不溶性的，成膜聚合物d）0〜15重量的水溶性聚合物的％，和e）0-15重量％的其它药学上常用的赋形剂，其中组分的总和a）至e）为100重量％是 ，
-
7.发明申请PHARMACEUTICAL FORMULATION FOR THE PRODUCTION OF RAPIDLY DISINTEGRATING TABLETS 审中-公开药物制剂FOR FAST崩解片剂的制造
公开(公告)号：WO2008148742A3
公开(公告)日：2009-08-13
申请号：PCT/EP2008056805
申请日：2008-06-03
Applicant: BASF SE , KOLTER KARL , SCHOENHERR MICHAEL , GEBERT SILKE , MEYER-BOEHM KATHRIN , MASCHKE ANGELIKA
Inventor： KOLTER KARL , SCHOENHERR MICHAEL , GEBERT SILKE , MEYER-BOEHM KATHRIN , MASCHKE ANGELIKA
CPC classification number: A61K9/2018 , A61K9/0056 , A61K9/2027 , A61K9/2054
Abstract: The invention relates to a pharmaceutical formulation in the form of agglomerates containing A) an adjuvant consisting of a) 60 - 97 % by weight of sugar or sugar alcohols, b) 1 - 25 % by weight of a disintegration agent c)1 - 15 % by weight of water insoluble, film-forming polymers d) 0 -15 % by weight of water soluble polymers, and e) 0 - 15 % by weight of additional conventional pharmaceutical adjuvants, the sum of the components a) to e) totalling 100 % by weight, and B) at least one active ingredient.
Abstract translation: 在包含A）赋形剂馏分聚集体形式的药物制剂，包括一个）60 -97重量％的糖或糖醇的，B）1 - 25重量的崩解剂％，C）1-15重量％的水不溶性成膜聚合物d ）0 -15重量的水溶性聚合物的％，和e）0 - 15重量％的其它药学上常用的赋形剂，其中组分的总和a）至e）重量％为100，和B）至少一种活性成分。
-
公开(公告)号：DE502006006364D1
公开(公告)日：2010-04-15
申请号：DE502006006364
申请日：2006-11-30
Applicant: BASF SE
Inventor： BOUILLO NATHALIE , KHVOROST ALEXANDER , MUENSTER INGO , DOBRAWA RAINER , MEYER-BOEHM KATHRIN , LANGE RONALD FRANS MARIA
Abstract: Vinyllactam copolymers modified with polyalkylene oxide side-chains, and use thereof as solubilizers for substances which are sparingly soluble in water, and preparations comprising such copolymers.
-
公开(公告)号：MX2009013063A
公开(公告)日：2010-01-15
申请号：MX2009013063
申请日：2008-06-03
Applicant: BASF SE
Inventor： KOLTER KARL , SCHOENHERR MICHAEL , GEBERT SILKE , MEYER-BOEHM KATHRIN , MASCHKE ANGELIKA
Abstract: La invención se refiere a una formulación farmacéutica en forma de aglomerados, que contiene A) un adyuvante que consiste de a) 60-97% en peso de azúcar o alcoholes de azúcar, b) 1-25% en peso de un agente de desintegración, c) 1-15% en peso de polímeros formadores de película, insolubles en agua, d) 0-15% en peso de polímeros solubles en agua, y e) 0-15% en peso de adyuvantes farmacéuticos convencionales adicionales, la suma de los componentes a) hasta e) forman un total de 100% en peso, y B) por lo menos un ingrediente activo.
-
公开(公告)号：CL2019000123A1
公开(公告)日：2019-04-05
申请号：CL2019000123
申请日：2019-01-16
Applicant: BASF SE
Inventor： MEYER-BOEHM KATHRIN , HELGASON THRANDUR , SINGH RAAJVINDER , DOBLER WALTER , SCHORDING PETER , WIGBERS CHRISTOF WILHELM , KOLTER KARL , BRUHNS STEFAN , PELLETIER WOLF , WAGNER DANIEL
IPC: A23K20/174 , A23L33/155 , A23P10/20 , A61K8/31 , A61K31/07 , C07C403/24
Abstract: FORMULACIÓN PULVERULENTA DE VITAMINA DONDE LA VITAMINA ESENCIALMENTE TIENE TAMAÑO DE PARTÍCULA MENOR A 0,7 µM, QUE COMPRENDE UNA CANTIDAD EFICAZ DE GALATO DE PROPILO, PROCESOS PARA PRODUCIRLA, FORMULACIONES QUE PUEDEN OBTENERSE MEDIANTE ESTOS PROCESOS Y SU UTILIZACIÓN COMO ALIMENTO PARA ANIMALES, ALIMENTOS, SUPLEMENTOS ALIMENTICIOS, PRODUCTOS PARA CUIDADO PERSONAL O COMPOSICIONES FARMACÉUTICAS. LAS FORMULACIONES DE LA INVENCIÓN TIENEN ESTABILIDAD MEJORADA EN COMPARACIÓN CON LA TÉCNICA ANTERIOR.
-
-
-
-
-
-
-
-
-
Search Results
19
records
(took 0.02 seconds)
