公开(公告)号：ES2367847T3

公开(公告)日：2011-11-10

申请号：ES06841443

申请日：2006-12-19

Applicant: BASF SE

Inventor： SCHAEDLER ANDREAS ,  FRIEDRICH THOMAS ,  STUERMER RAINER ,  RINCK-JAHNKE SABINE

IPC: C12P7/24 ,  C12N9/02

Abstract: Método para la producción de aldehídos o alcoholes saturados ópticamente activos de la fórmula (2) a partir de aldehídos αβ- insaturados de la fórmula (1) mediante reducción en presencia de una enoato-reductasa (i) con la secuencia de polipéptidos SEQ ID NO:1 o 2, o (ii) con una secuencia de polipéptidos la cual exhibe por lo menos 80% de identidad de secuencia con SEQ ID NO:1 o 2. donde R 1 y R 2 significan independientemente uno de otro H, alquilo C1-C4, R 3 significa H, alquilo o alquenilo C1-C6 en forma ramificada y no ramificada.

公开(公告)号：CA3005292A1

公开(公告)日：2017-06-15

申请号：CA3005292

申请日：2016-12-08

Applicant: BASF SE

Inventor： TREIER-MARXEN KATRIN ,  DECKERT PETRA ,  SCHAEDLER ANDREAS ,  NAVICKAS VAIDOTAS ,  WENGERT VOLKER ,  KAEDING THOMAS

IPC: B01D61/16 ,  C07K1/14 ,  C12N1/02

Abstract: The present invention is directed to a method of purifying a protein of interest from the particulate matter of a fermentation broth comprising the step of purifying the protein of interest from the particulate matter of the fermentation broth, wherein the step of purifying the protein of interest from the particulate matter of the fermentation broth comprises one or more washing steps, which comprises contacting the particulate matter with a washing solution comprising one or more conditions that favor the solubilization of the protein of interest and/or the desorption of the protein of interest from the particulate matter.

公开(公告)号：AT513054T

公开(公告)日：2011-07-15

申请号：AT06841443

申请日：2006-12-19

Applicant: BASF SE

Inventor： SCHAEDLER ANDREAS ,  FRIEDRICH THOMAS ,  STUERMER RAINER ,  RINCK-JAHNKE SABINE

IPC: C12P7/24 ,  C12N9/02

Abstract: Preparation of an optically active saturated aldehyde or alcohol (II) comprises reduction of alpha , beta unsaturated aldehyde (I) with a polypeptide sequence (SEQ ID NO: 1 or 2), or a polypeptide sequence exhibiting at least 80% sequence identity of (SEQ ID NO: 1 or 2), in the presence of an enoate reductase. Preparation of an optically active saturated aldehyde or alcohol of formula (II) comprises reduction of alpha , beta unsaturated aldehyde (I) of formula (R 3>-C(R 2>)=C(R 1>)-CH(=O)) with a polypeptide sequence (SEQ ID NO: 1 or 2) (not defined), or a polypeptide sequence exhibiting at least 80% sequence identity of (SEQ ID NO: 1 or 2), in the presence of a enoate reductase. R 1>, R 2>H or 1-4C-alkyl; and R 3>H or 1-6C alkyl or alkenyl. [Image].