公开(公告)号：DE69505391T2

公开(公告)日：1999-06-17

申请号：DE69505391

申请日：1995-06-29

Applicant: BAXTER INT

Inventor： GELLER ROBIN ,  BRAUKER JAMES ,  JOHNSTON WILLIAM ,  LEVON STEVEN ,  MARYANOV DAVID

IPC: A61K9/00 ,  A61K35/12 ,  A61K35/13 ,  A61K38/00 ,  A61K38/19 ,  A61K39/00 ,  A61P35/00 ,  A61J9/00

Abstract: An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.

公开(公告)号：DE69505391D1

公开(公告)日：1998-11-19

申请号：DE69505391

申请日：1995-06-29

Applicant: BAXTER INT

Inventor： GELLER ROBIN ,  BRAUKER JAMES ,  JOHNSTON WILLIAM ,  LEVON STEVEN ,  MARYANOV DAVID

IPC: A61K9/00 ,  A61K35/12 ,  A61K35/13 ,  A61K38/00 ,  A61K38/19 ,  A61K39/00 ,  A61P35/00 ,  A61J9/00

Abstract: An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.