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公开(公告)号:DE69505391D1
公开(公告)日:1998-11-19
申请号:DE69505391
申请日:1995-06-29
Applicant: BAXTER INT
Inventor: GELLER ROBIN , BRAUKER JAMES , JOHNSTON WILLIAM , LEVON STEVEN , MARYANOV DAVID
Abstract: An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.
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公开(公告)号:DE69216820D1
公开(公告)日:1997-02-27
申请号:DE69216820
申请日:1992-09-25
Applicant: BAXTER INT
Inventor: WOO LECON , LO YING , LING MICHAEL , LAURIN DEAN , GLEASON BYRON , BUAN LILLIAN , JOHNSTON WILLIAM
IPC: A61J1/10 , B29C65/00 , B29C65/04 , B29C65/52 , B29L9/00 , B29L22/00 , B32B7/02 , B65D65/42 , B65D75/30 , A61M1/14
Abstract: The coating of a RF active material on a non-RF active substrate material of typical thickness for packaging purposes, can generate sufficient thermal energy to effect strong bonding of the substrate materials. The RF active material may be-deposited on less than the entire inner surface area of the substrate material, preferably, at or near the portion of the substrate surface which represents the heat seal interface. In this manner of application, additional coating or printing of other substances on the substrate surface can be achieved without hampering the heat sealing process. Flexible medical containers capable of containing a product which is maintained and removed under sterile conditions, can be constructed on commercial production machines from these coated non-RF active substrate materials.
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公开(公告)号:DE69505391T2
公开(公告)日:1999-06-17
申请号:DE69505391
申请日:1995-06-29
Applicant: BAXTER INT
Inventor: GELLER ROBIN , BRAUKER JAMES , JOHNSTON WILLIAM , LEVON STEVEN , MARYANOV DAVID
Abstract: An implantable device for the prevention or treatment of cancer comprising an implantable chamber containing tumor cells, or somatic cells engineered to express at least one antigen corresponding to antigen of a patient's tumor; the chamber having a porous wall to provide, in use, a porous boundary between the patient's immune cells and the contained cells; the porosity of the boundary being sufficient to permit subcellular antigenic material to pass through the boundary, while preventing the contained cells and patient immune cells from passing through the boundary.
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公开(公告)号:DE69216820T2
公开(公告)日:1997-08-14
申请号:DE69216820
申请日:1992-09-25
Applicant: BAXTER INT
Inventor: WOO LECON , LO YING , LING MICHAEL , LAURIN DEAN , GLEASON BYRON , BUAN LILLIAN , JOHNSTON WILLIAM
IPC: A61J1/10 , B29C65/00 , B29C65/04 , B29C65/52 , B29L9/00 , B29L22/00 , B32B7/02 , B65D65/42 , B65D75/30 , A61M1/14
Abstract: The coating of a RF active material on a non-RF active substrate material of typical thickness for packaging purposes, can generate sufficient thermal energy to effect strong bonding of the substrate materials. The RF active material may be-deposited on less than the entire inner surface area of the substrate material, preferably, at or near the portion of the substrate surface which represents the heat seal interface. In this manner of application, additional coating or printing of other substances on the substrate surface can be achieved without hampering the heat sealing process. Flexible medical containers capable of containing a product which is maintained and removed under sterile conditions, can be constructed on commercial production machines from these coated non-RF active substrate materials.
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