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公开(公告)号：WO2004058046A3
公开(公告)日：2009-06-18
申请号：PCT/US0339973
申请日：2003-12-16
Applicant: BAXTER INT
Inventor： JOHNSON KENNETH M , DAHAN MEIR , SHADMAN SOHAIL , JONES MARK B , WEST RICHARD L , LO YING-CHENG , MUI TAT CHI , AKONUR ALP , YARDIMCI ATIF , DAVIS SHAWN , ZHIZHIN NIKOLAY , KILLE ERIC J , WESTBERG TOM , LABONTE JUDITH , JOHNSTON JOHN F , OTTINO JULIO , LEIBSON ABRAHAM , PENNINGTON DAVID W , PAWLAK KENNETH E , MORIARITY JULIE A , SLEPICKA JANE S
CPC classification number: A61M1/3692 , A61M1/02 , A61M1/0218 , A61M1/1006 , A61M1/1039 , A61M1/1081 , A61M1/3679 , A61M1/3687 , A61M39/221 , A61M2039/222 , A61M2205/12 , A61M2206/22
Abstract: Treatment apparatus, system and method are disclosed for treating a biological fluid, such as blood or blood components. The treatment may include but isnot limited to inactivation of pathogens in red cell concentrate. The system may include a disposable fluid circuit assembly and a reusable controller that controls flow through the fluid circuit for reconstituting, if necessary, a treating agent, combining the treating agent with a biological fluid and mixing the agent and biological fluid. An optional quenching agent may also be used.
Abstract translation: 公开了用于处理诸如血液或血液成分的生物流体的处理装置，系统和方法。 治疗可能包括但不限于红细胞浓缩物中病原体的灭活。 该系统可以包括一次性流体回路组件和可重复使用的控制器，其控制通过流体回路的流动，以便如果需要，重组处理剂，将处理剂与生物流体混合并混合该试剂和生物流体。 也可以使用任选的淬火剂。
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公开(公告)号：WO0230489A2
公开(公告)日：2002-04-18
申请号：PCT/US0142350
申请日：2001-09-28
Applicant: BAXTER INT
Inventor： RUDDELL SCOTT , YARDIMCI ATIF , DEL CASTILLO JORGE
Abstract: A catheter suitable for use in performing peritoneal dialysis. The catheter is a dual lumen catheter which allows for continuous flow peritoneal dialysis. Dialysate flows through the catheter into the patient via one lumen and simultaneously flows through the catheter out of the patient via the second lumen. The dual lumen dialysis catheter has a flexible tube which has an implantable portion extending from an external patient portion. Both of the lumens have openings in the external patient portion for connecting to a supply and drain of dialysate, respectively. The implantable portion has a preformed curved segment which has an outlet for the first lumen to flow dialysate into the patient's peritoneal cavity. The implantable portion has an opening for the second lumen at the distal end to flow dialysate out of the peritoneal cavity and removal from the patient. The catheter facilitates mixing of fresh and spent dialysate inside the peritoneal cavity by inflowing fresh dialysate into the cavity at a location substantially separated from the cavity outflow location, and by directing the inflow of dialysate into the cavity opposite the cavity outflow location.
Abstract translation: 适合用于进行腹膜透析的导管。 导管是双腔导管，允许腹膜透析连续流动。 透析液通过一个管腔穿过导管流入患者体内，并同时经由第二管腔从患者体内流出。 双腔透析导管具有柔性管，其具有从外部患者部分延伸的可植入部分。 两个管腔在外部患者部分都具有开口，用于分别连接到透析液的供应和排出。 可植入部分具有预成型的弯曲部分，其具有用于第一内腔的透出液将透析液流入患者腹膜腔的出口。 可植入部分具有用于在远端处的第二腔的开口，以将透析液从腹膜腔中流出并从患者身上移除。 通过在与空腔流出位置基本上分离的位置处将新鲜透析液流入空腔中，并且通过将透析液的流入引导到与空腔流出位置相对的空腔中，导管便于在腹膜腔内混合新鲜和用过的透析液。
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3.发明申请
公开(公告)号：WO2009089213A4
公开(公告)日：2010-03-04
申请号：PCT/US2009030210
申请日：2009-01-06
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , DELCASTILLO JORGE , YARDIMCI ATIF
Inventor： DELCASTILLO JORGE , YARDIMCI ATIF
IPC: A61M5/168
CPC classification number: A61M5/14212 , A61M5/16831 , A61M2205/3331 , A61M2205/3334
Abstract: A method and system for detecting an inclusion within an infusion system. The method includes monitoring an output signal of a flowrate sensor as fluid flows through an infusion system. The output signal is then converted with a noise reduction filter to obtain a filtered output signal. The filtered output signal is compared to a threshold value and an alarm is activated if the filtered output signal falls below a desired threshold, thereby indicating an occlusion within the infusion system.
Abstract translation: 一种用于检测输注系统内的夹杂物的方法和系统。 该方法包括当流体流过输注系统时监测流量传感器的输出信号。 然后用噪声减少滤波器转换输出信号以获得滤波的输出信号。 将滤波的输出信号与阈值进行比较，并且如果滤波的输出信号低于期望的阈值，则激活报警，从而指示输注系统内的闭塞。
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4.发明申请
公开(公告)号：WO2009089213A3
公开(公告)日：2010-01-07
申请号：PCT/US2009030210
申请日：2009-01-06
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , DELCASTILLO JORGE , YARDIMCI ATIF
Inventor： DELCASTILLO JORGE , YARDIMCI ATIF
IPC: A61M5/168
CPC classification number: A61M5/14212 , A61M5/16831 , A61M2205/3331 , A61M2205/3334
Abstract: A method and system for detecting an inclusion within an infusion system. The method includes monitoring an output signal of a flowrate sensor as fluid flows through an infusion system. The output signal is then converted with a noise reduction filter to obtain a filtered output signal. The filtered output signal is compared to a threshold value and an alarm is activated if the filtered output signal falls below a desired threshold, thereby indicating an occlusion within the infusion system.
Abstract translation: 一种用于检测输注系统内的夹杂物的方法和系统。 该方法包括当流体流过输注系统时监测流量传感器的输出信号。 然后用噪声降低滤波器转换输出信号以获得滤波的输出信号。 将滤波后的输出信号与阈值进行比较，并且如果滤波的输出信号低于期望的阈值，则报警被激活，从而指示输注系统内的闭塞。
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公开(公告)号：WO2005044418A2
公开(公告)日：2005-05-19
申请号：PCT/US2004029637
申请日：2004-09-08
Applicant: BAXTER INT , REITZ DOUGLAS W , ARIAGNO SCOTT , SHETH MIHIR , YARDIMCI ATIF , CLARKE ROBERT A , PENNINGTON DAVID W , PRISCO MICHAEL R , CHIM EDWIN , PAULEY ROBIN , SANDFORD CRAIG , SITES ARCH
Inventor： REITZ DOUGLAS W , ARIAGNO SCOTT , SHETH MIHIR , YARDIMCI ATIF , CLARKE ROBERT A , PENNINGTON DAVID W , PRISCO MICHAEL R , CHIM EDWIN , PAULEY ROBIN , SANDFORD CRAIG , SITES ARCH
CPC classification number: A61M1/3633 , A61M1/0222 , A61M1/3687 , A61M2205/75
Abstract: Flow-through systems for processing biological fluid are disclosed. The flow-through systems include a removal device in the flow path for removing unwanted compounds and agents. The removal device includes a removal media contained within a housing made of two separate portions sealed together. The housing is maintained in a substantially vertical disposition, thereby ensuring substantially uniform and complete exposure of the fluid to the media.
Abstract translation: 公开了用于处理生物流体的流通系统。 流通系统包括流路中的去除装置，用于去除不需要的化合物和试剂。 去除装置包括容纳在由密封在一起的两个单独部分制成的壳体内的移除介质。 壳体保持基本垂直的布置，从而确保流体基本均匀和完全地暴露于介质。
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Patent Agency Ranking
公开(公告)号：WO03039375A2
公开(公告)日：2003-05-15
申请号：PCT/US0231985
申请日：2002-10-07
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： SPERO RICHARD , YARDIMCI ATIF , EPSTEIN GORDON
CPC classification number: B05C17/00593 , A61B17/00491 , B05C17/00516
Abstract: A laparoscopic spray device for selectively applying a multiple component material dispensed from a multiple component material applicator to a surgical site in vivo is disclosed. The device comprises an interface member capable of engaging a multiple component applicator, a body having at least two lumens therein, and a detachable spray tip in fluid communication with the body. The detachable spray tip includes a mixing chamber having at least one flexible mixing member positioned therein which is capable of creating a turbulent flow within a mixing chamber. In addition, the at least one mixing member prevents a back flow of material from the mixing chamber to the at least two lumens. The present invention is particularly useful in remotely applying multiple component tissue adhesives to an internal incision.
Abstract translation: 公开了一种用于选择性地将从多组分材料施用器分配的多组分材料施用于体内的手术部位的腹腔镜喷雾装置。 该装置包括能够接合多组分施加器的接口构件，其中具有至少两个腔的主体和与身体流体连通的可拆卸喷雾尖端。 可拆卸喷嘴包括具有定位在其中的至少一个柔性混合构件的混合室，其能够在混合室内产生湍流。 此外，至少一个混合构件防止材料从混合室向后流动至至少两个流明。 本发明特别适用于将多组分组织粘合剂远程应用于内部切口。
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公开(公告)号：ES2428714T3
公开(公告)日：2013-11-11
申请号：ES09701001
申请日：2009-01-06
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： DELCASTILLO JORGE , YARDIMCI ATIF
Abstract: Método para la detección de una oclusión en el interior de un sistema de infusión (10) que comprende: supervisar una señal de salida procedente de un sensor de caudal (26) cuando el fluido fluye a través del sistema de infusión (10); adquirir una línea base de la señal de salida del sensor de caudal; filtrar la línea base con un filtro de promedio para calcular la línea base media; calcular un nivel umbral (41) en función de la línea base media; filtrar la señal de salida con un filtro reductor de ruido para obtener una señal de salida filtrada; y activar una alarma (56), indicativa de una oclusión, si la señal de salida filtrada está por debajo de dicho nivel umbral .
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公开(公告)号：AU2013201419A1
公开(公告)日：2013-04-04
申请号：AU2013201419
申请日：2013-03-12
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： DELCASTILLO JORGE , YARDIMCI ATIF
IPC: A61M5/168
Abstract: A method of detecting an occlusion for an infusion therapy including obtaining a baseline output from a flowrate sensor; filtering the baseline output to form a filtered baseline output; determining an upper threshold value and a lower threshold value from the filtered baseline output; monitoring a therapy output of the flowrate sensor during the infusion therapy; filtering the therapy output to produce a filtered therapy output; and comparing the filtered therapy output to (i) the lower threshold value to determine if an occlusion is present upstream of the flowrate sensor, and (ii) the upper threshold value to determine if an occlusion is present downstream from the flowrate sensor. 12/gn/q FLONFLUD THROU GH; INFUSiN YSTEM- RATE SENSOR.AS FLU0 FLOSS THRJG 212 SUCASVOLlSOR ELECTRrCCURREN) CAPTURE A D',ATA 8FETHAT 214 INCLUDES TlE OtfrPUT S'IGNAL AS A FUNCTON OF TiME. APPLY A4 IN E REJEC TION FILTER TO 216 THE DATAk SET APPLYY A ULWPA-S PEFOM PETRAAkAYSGS F0LTRE 2i8 DATA SET (EAPPLY FFT TO CC#RT RATA S T TO FREQUJENCY DOMAI CACULTE T HE S CGNAL S TRENG3TH OVER A RANE OFFEU YT;HAT22 CORRELATES TO THE PMRNG FREQUENCY EG.. INTEGRATE THE 224 POR i1ffPECTN TEFREQUENCY DOXMN FO THE FREQENCY RANGE AND COMPUTE THE ENERGY METHOD) 222 CMAE TE SS GNAL STRENGTH CME THE SG0A STRENGTH 4 l TO AN UPPER TOA LOWER THRESH)0D T;HRESHOLD0 SRNGTH NO TRNTH NO BELOW LVWR AKOV UPPER TRSHOLD? THRESHOLD7 ACT!-VATE ALARM N.DCAilG 228 CIAEAAR3DCTN ANOCCLiONUMPSTRFJ4M OF ANOCCLUSIONDUMSEAM r232 THE FLOW RATE SE NSOiR OF THE FLOWvRATE SENSOR
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公开(公告)号：CA2462498C
公开(公告)日：2010-12-14
申请号：CA2462498
申请日：2002-10-07
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： SPERO RICHARD , YARDIMCI ATIF , EPSTEIN GORDON
Abstract: A laparoscopic spray device for selectively applying a multiple component material dispensed from a multiple component material applicator to a surgical site in vivo is disclosed. The device comprises an interface member capable of engaging a multiple component applicator, a body having at least two lumens therein, and a detachable spray tip in fluid communication with the body. The detachable spray tip includes a mixing chamber having at least one flexible mixing member positioned therein which is capable of creating a turbulent flow within a mixing chamber. In addition, the at least one mixing member prevents a back flow of material from the mixing chamber to the at least two lumens. The present invention is particularly useful in remotely applying multiple component tissue adhesives to an internal incision.
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公开(公告)号：AU2009204243A1
公开(公告)日：2009-07-16
申请号：AU2009204243
申请日：2009-01-06
Applicant: BAXTER HEALTHCARE SA , BAXTER INT
Inventor： DELCASTILLO JORGE , YARDIMCI ATIF
IPC: A61M5/168
Abstract: A method of detecting an occlusion within an infusion system, comprising: monitoring an output signal from a flowrate sensor as a pulsatile fluid flow having a frequency flows through the infusions system; acquiring a data set that includes the output signal as a function of time; filtering the data set with a noise rejection filter to produce a filtered data set; performing spectra analysis on the filtered data set to determine strength of the output signal in a frequency domain; calculating a signal strength for a frequency range that correlates to the frequency of the pulsatile fluid flow; and comparing the signal strength of the range to at least one threshold level to determine if an occlusion is present within the infusion system.
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