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公开(公告)号：WO2010002830A4
公开(公告)日：2010-07-29
申请号：PCT/US2009049152
申请日：2009-06-30
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , YEH ROSA , XIE WEI , YANG HSINJIN , LING MICHAEL , LO YING-CHENG
Inventor： YEH ROSA , XIE WEI , YANG HSINJIN , LING MICHAEL , LO YING-CHENG
CPC classification number: A61M1/3486 , A61M1/14 , A61M1/16 , A61M1/1619 , A61M1/1696 , A61M1/28 , A61M1/284 , A61M1/34 , A61M1/3406 , A61M1/3413 , A61M1/3472 , A61M2202/0498 , A61M2205/0211 , A61M2205/12 , A61M2205/125 , A61M2205/126 , A61M2205/15 , A61M2205/3331 , A61M2205/3368 , A61M2205/50 , A61M2205/75 , A61M2209/088
Abstract: Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. Nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The clays may be used in wearable systems, such as a wearable peritoneal dialysis system, in which the dialysis fluid is circulated through a filter with nanoclay sorbents. Waste products are absorbed by the nanoclays and the dialysis fluid is recycled to the patient's peritoneum. Using the ion-exchange capability of the nanoclays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate. The nanoclay sorbents are also useful for refreshing dialysis fluid used in hemodialysis and thus reducing the quantity of dialysis fluid needed for hemodialysis.
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Patent Agency Ranking
公开(公告)号：WO2010002830A2
公开(公告)日：2010-01-07
申请号：PCT/US2009049152
申请日：2009-06-30
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , YEH ROSA , XIE WEI , YANG HSINJIN , LING MICHAEL , LO YING-CHENG
Inventor： YEH ROSA , XIE WEI , YANG HSINJIN , LING MICHAEL , LO YING-CHENG
CPC classification number: A61M1/3486 , A61M1/14 , A61M1/16 , A61M1/1619 , A61M1/1696 , A61M1/28 , A61M1/284 , A61M1/34 , A61M1/3406 , A61M1/3413 , A61M1/3472 , A61M2202/0498 , A61M2205/0211 , A61M2205/12 , A61M2205/125 , A61M2205/126 , A61M2205/15 , A61M2205/3331 , A61M2205/3368 , A61M2205/50 , A61M2205/75 , A61M2209/088
Abstract: Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. Nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The clays may be used in wearable systems, such as a wearable peritoneal dialysis system, in which the dialysis fluid is circulated through a filter with nanoclay sorbents. Waste products are absorbed by the nanoclays and the dialysis fluid is recycled to the patient's peritoneum. Using the ion-exchange capability of the nanoclays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate. The nanoclay sorbents are also useful for refreshing dialysis fluid used in hemodialysis and thus reducing the quantity of dialysis fluid needed for hemodialysis.
Abstract translation: 通过使用纳米粘土吸附剂更好地吸收流通系统中的身体废物来增强透析。 使用蒙脱石，膨润土和其他粘土的Nanoclay吸附剂比常规吸附剂更能吸收更多的铵，磷酸盐和肌酸酐等。 粘土可用于可佩戴的系统中，例如穿戴式腹膜透析系统，其中透析液体通过具有纳米粘土吸附剂的过滤器循环。 废物被纳米粘土吸收，透析液再循环到患者腹膜。 使用纳米粘土的离子交换能力，透析液中的废离子被替换为理想的离子，例如钙，镁和碳酸氢盐。 纳米粘土吸附剂也可用于清除血液透析中使用的透析液，从而减少血液透析所需的透析液量。
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公开(公告)号：AT549049T
公开(公告)日：2012-03-15
申请号：AT09774281
申请日：2009-06-30
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor： YEH ROSA , XIE WEI , YANG HSINJIN , LING MICHAEL , LO YING-CHENG
Abstract: A dialysis system (40, 50) is described. The system comprises a filter (10, 30) having a housing (11, 34) and a linear bundle of hollow fibers (18, 20) with (i) processed nanoclay particles (25) embedded in the walls of the fibers (18, 20) or (ii) processed nanoclay particles (25) within a lumen of the fibers (18, 20). The processed nanoclay particles (25) have at least one dimension from about 1 nm to about 200 nm, are configured to absorb waste product ions from the dialysis fluid, and comprise ions for refreshing and renewing the dialysis fluid by replacing the waste product ions to produce a refreshed and renewed dialysis fluid that is suitable for reuse. The filter (10, 30) is configured to allow a used dialysis fluid to flow through the filter (10, 30).
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公开(公告)号：AU2003237362A1
公开(公告)日：2003-12-31
申请号：AU2003237362
申请日：2003-06-03
Applicant: BAXTER INT
Inventor： YEH ROSA , TANDON RAHUL , KAROOR SUJATHA , PAULEY ROBIN , BOGGS DANIEL
Abstract: Membranes impregnated with cross-linked enzyme crystals and devices, systems and methods of producing and using same are provided. The present invention includes membranes impregnated with a sufficient amount of a cross-linked enzyme crystal(s), such as membranes impregnated with cross-linked urease crystals. The membrane can been dried in a glycerol solution prior to use.
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公开(公告)号：AU2003237362A8
公开(公告)日：2003-12-31
申请号：AU2003237362
申请日：2003-06-03
Applicant: BAXTER HEALTHCARE SA , BAXTER INT
Inventor： YEH ROSA , TANDON RAHUL , KAROOR SUJATHA , PAULEY ROBIN , BOGGS DANIEL
Abstract: Membranes impregnated with cross-linked enzyme crystals and devices, systems and methods of producing and using same are provided. The present invention includes membranes impregnated with a sufficient amount of a cross-linked enzyme crystal(s), such as membranes impregnated with cross-linked urease crystals. The membrane can been dried in a glycerol solution prior to use.
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公开(公告)号：AU2002334629A1
公开(公告)日：2003-06-30
申请号：AU2002334629
申请日：2002-09-20
Applicant: BAXTER INT
Inventor： PAN LI , STERNBERG SHMUEL , BOGGS DANIEL , YEH ROSA
IPC: G01N31/22
Abstract: A membrane capable of sensing gaseous phase ammonia is provided. The membrane includes a hydrophobic membrane layer that has a microporous structure and a pH sensitive dye embedded within the microporous structure such that the membrane is capable of calorimetrically sensing a change in ammonia with a high degree of sensitivity and responsiveness as applied to, for example, a change in ammonia dissolved in a dialysis solution during dialysis therapy.
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