公开(公告)号：CA2720615A1

公开(公告)日：2009-10-15

申请号：CA2720615

申请日：2009-04-07

Applicant: BIO RAD LABORATORIES

Inventor： GAGNON PETER S ,  CHEN HONG ,  FROST RUSS

IPC: A23J1/00

Abstract: Methods, kits and apparatuses for chromatography purification of antibodies are provided. In some embodiments, antibodies are purified by mixed mode chromatography that does not comprise hydroxyapatite (HT) or fluorapatite (FT). The mixed mode chromatography step is then followed by a HT/FT chromatography step.

公开(公告)号：CA2720615C

公开(公告)日：2016-06-07

申请号：CA2720615

申请日：2009-04-07

Applicant: BIO-RAD LABORATORIES INC

Inventor： GAGNON PETER S ,  CHEN HONG ,  FROST RUSS

IPC: C07K16/00 ,  A23J1/00 ,  B01D15/10 ,  C07K1/16 ,  C07K1/22

Abstract: Methods, kits and apparatuses for chromatography purification of antibodies are provided. In some embodiments, antibodies are purified by mixed mode chromatography that does not comprise hydroxyapatite (HT) or fluorapatite (FT). The mixed mode chromatography step is then followed by a HT/FT chromatography step.

公开(公告)号：EP2265129A4

公开(公告)日：2012-06-06

申请号：EP09729752

申请日：2009-04-07

Applicant: BIO RAD LABORATORIES

Inventor： GAGNON PETER S ,  CHEN HONG ,  FROST RUSS

IPC: A23J1/00 ,  B01D15/36 ,  B01D15/38

CPC classification number: C07K16/065 ,  A61K39/39591 ,  B01D15/36 ,  B01D15/3847 ,  C07K1/14 ,  C07K1/36 ,  C07K2317/24 ,  C07K2317/50