公开(公告)号：CA2450385A1

公开(公告)日：2003-01-09

申请号：CA2450385

申请日：2002-06-19

Applicant: BIO RAD LABORATORIES

Inventor： NAGHIEH HAMID R ,  KOTCHOU KEITH ,  BHATT NEERAJ ,  GINGRICH JEFFREY

IPC: G01N21/64 ,  G01N21/27 ,  G01N27/447 ,  G01N27/26

Abstract: The optical imaging of two-dimensional solute zone arrays in electrophoresis gels is corrected for nonuniformities in the optical system such as those arising from the light source or from light dispersion underneath the gel. T he correction is achieved by the use of a reference plate that responds to a light source uniformly along its length and width by being either uniformly light absorptive or uniformly light transmissive, or by emitting light upon excitation. Thus, any nonuniformities or deviations in the image of the reference plate arise only from nonuniformities or deviations within the optical system. Analogous corrections are made in other two-dimensional assa y images, such as microarrays and microtiter plates.

公开(公告)号：AU2002344839B2

公开(公告)日：2006-05-11

申请号：AU2002344839

申请日：2002-06-19

Applicant: BIO RAD LABORATORIES

Inventor： NAGHIEH HAMID R ,  GINGRICH JEFFREY ,  KOTCHOU KEITH ,  BHATT NEERAJ

IPC: G01N21/64 ,  G01N27/26 ,  G01N21/27 ,  G01N27/447

Abstract: The optical imaging of two-dimensional solute zone arrays in electrophoresis gels is corrected for nonuniformities in the optical system such as those arising from the light source or from light dispersion underneath the gel. The correction is achieved by the use of a reference plate that responds to a light source uniformly along its length and width by being either uniformly light absorptive or uniformly light transmissive, or by emitting light upon excitation. Thus, any nonuniformities or deviations in the image of the reference plate arise only from nonuniformities or deviations within the optical system. Analogous corrections are made in other two-dimensional assay images, such as microarrays and microtiter plates.

公开(公告)号：CA2450385C

公开(公告)日：2007-11-13

申请号：CA2450385

申请日：2002-06-19

Applicant: BIO RAD LABORATORIES

Inventor： NAGHIEH HAMID R ,  BHATT NEERAJ ,  KOTCHOU KEITH ,  GINGRICH JEFFREY

IPC: G01N21/64 ,  G01N21/93 ,  G01N21/27 ,  G01N27/447 ,  G01N33/483

Abstract: The optical imaging of two-dimensional solute zone arrays in electrophoresis gels is corrected for nonuniformities in the optical system such as those arising from the light source or from light dispersion underneath the gel. T he correction is achieved by the use of a reference plate that responds to a light source uniformly along its length and width by being either uniformly light absorptive or uniformly light transmissive, or by emitting light upon excitation. Thus, any nonuniformities or deviations in the image of the reference plate arise only from nonuniformities or deviations within the optical system. Analogous corrections are made in other two-dimensional assa y images, such as microarrays and microtiter plates.

公开(公告)号：EP1410005A4

公开(公告)日：2007-07-11

申请号：EP02744465

申请日：2002-06-19

Applicant: BIO RAD LABORATORIES

Inventor： NAGHIEH HAMID R ,  KOTCHOU KEITH ,  BHATT NEERAJ ,  GINGRICH JEFFREY

IPC: G01N21/64 ,  G01N21/27 ,  G01N27/447

CPC classification number: G01N27/44721 ,  G01N21/276

Abstract: The optical imaging of two-dimensional solute zone arrays in electrophoresis gels is corrected for nonuniformities in the optical system such as those arising from the light source or from light dispersion underneath the gel. The correction is achieved by the use of a reference plate that responds to a light source uniformly along its length and width by being either uniformly light absorptive or uniformly light transmissive, or by emitting light upon excitation. Thus, any nonuniformities or deviations in the image of the reference plate arise only from nonuniformities or deviations within the optical system. Analogous corrections are made in other two-dimensional assay images, such as microarrays and microtiter plates.