公开(公告)号：CA2827536A1

公开(公告)日：2012-09-13

申请号：CA2827536

申请日：2012-03-05

Applicant: BIO RAD LABORATORIES

Inventor： TAN WOEI ,  MONJI NOBUO ,  GUPTA VINITA ,  REYES CANDICE

IPC: G01N33/53

Abstract: In sandwich-type immunoassays that capture a protein analyte between a capture antibody, typically bound to a solid phase, and a detection antibody that is coupled to a reporter group, the number of reporter groups associated with each molecule of analyte is increased by a variety of methods that utilize avidin-biotin-type binding in conjunction with such features as immunological binding to the reporter group on the detection antibody or multiple biotin-avidin-type binding sites.

公开(公告)号：WO2012122121A3

公开(公告)日：2014-02-27

申请号：PCT/US2012027764

申请日：2012-03-05

Applicant: BIO RAD LABORATORIES ,  TAN WOEI ,  MONJI NOBUO ,  GUPTA VINITA ,  REYES CANDICE

Inventor： TAN WOEI ,  MONJI NOBUO ,  GUPTA VINITA ,  REYES CANDICE

IPC: G01N33/543 ,  G01N33/532

CPC classification number: G01N33/54306 ,  G01N33/542

Abstract: In sandwich-type immunoassays that capture a protein analyte between a capture antibody, typically bound to a solid phase, and a detection antibody that is coupled to a reporter group, the number of reporter groups associated with each molecule of analyte is increased by a variety of methods that utilize avidin-biotin-type binding in conjunction with such features as immunological binding to the reporter group on the detection antibody or multiple biotin-avidin-type binding sites.

Abstract translation: 在通常与固相结合的捕获抗体和与报告基团连接的检测抗体之间捕获蛋白质分析物的夹心型免疫测定中，与每个分析物分子相关联的报告基团数量增加了多种 利用抗生物素蛋白 - 生物素型结合与检测抗体或多个生物素 - 抗生物素蛋白型结合位点等免疫学结合到报告基团的特征的方法。

公开(公告)号：EP2681557A4

公开(公告)日：2015-07-08

申请号：EP12754806

申请日：2012-03-05

Applicant: BIO RAD LABORATORIES

Inventor： TAN WOEI ,  MONJI NOBUO ,  GUPTA VINITA ,  REYES CANDICE

IPC: G01N33/543 ,  G01N33/532

CPC classification number: G01N33/54306 ,  G01N33/542