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1.发明公开CHROMOPHORE-BASED CHARACTERIZATION AND DETECTION METHODS 审中-公开CHROMOPHORENBASIERTE CHARAKTERISIERUNGS- UND ERKENNUNGSVERFAHREN
公开(公告)号：EP2948566A4
公开(公告)日：2016-10-05
申请号：EP14743745
申请日：2014-01-23
Applicant: CALIFORNIA INST OF TECHN
Inventor： RAJAGOPAL ADITYA , GOLDBERG MARK D , GARCIA ERIKA F , MADERO XIOMARA L , TOMBRELLO THOMAS A , SCHERER AXEL
IPC: C12Q1/68
CPC classification number: C12Q1/701 , C12Q1/68 , C12Q1/6851 , C12Q1/703 , Y10T436/143333 , C12Q2561/113 , C12Q2565/101 , C12Q2527/101 , C12Q2565/1015 , C12Q2565/133
Abstract: This disclosure provides methods, compositions and kits for the detection of a plurality of analytes in a sample. In some examples, this disclosure provides methods, compositions, and kits for detecting analytes, genetic variations, monitoring reaction process, and monitoring analyte-analyte interactions by measuring signals. In some examples, the presence of signals or changes in signals may be used to construct signal profiles which can be used to detect analytes.
Abstract translation: 本公开提供了用于检测样品中多种分析物的方法，组合物和试剂盒。 在一些实例中，本公开提供了用于检测分析物，遗传变异，监测反应过程以及通过测量信号监测分析物 - 分析物相互作用的方法，组合物和试剂盒。 在一些示例中，信号的存在或信号的改变可用于构建可用于检测分析物的信号谱。
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Patent Agency Ranking2.发明公开MULTIPLEXING AND QUANTIFICATION IN PCR WITH REDUCED HARDWARE AND REQUIREMENTS 审中-公开复用和量化与PCR技术降低了硬件并降低要求
公开(公告)号：EP2880184A4
公开(公告)日：2016-03-30
申请号：EP13824744
申请日：2013-08-02
Applicant: CALIFORNIA INST OF TECHN
Inventor： MALIK IMRAN R , MADERO XIOMARA L , GARCIA ERIKA F , SHAH SHEEL M , SCHERER AXEL
CPC classification number: G01N21/6486 , C12Q1/6851 , C12Q2537/143 , C12Q2537/165 , C12Q2565/629
Abstract: Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.
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公开(公告)号：EP2880420A4
公开(公告)日：2016-03-16
申请号：EP13825792
申请日：2013-07-22
Applicant: CALIFORNIA INST OF TECHN
Inventor： MALIK IMRAN R , MADERO XIOMARA L , GARCIA ERIKA F , SCHERER AXEL
CPC classification number: G01N21/64 , G01N21/0303 , G01N21/645
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公开(公告)号：IN1609DEN2015A
公开(公告)日：2015-07-03
申请号：IN1609DEN2015
申请日：2015-02-26
Applicant: CALIFORNIA INST OF TECHN
Inventor： MALIK IMRAN R , MADERO XIOMARA L , GARCIA ERIKA F , SHAH SHEEL M , SCHERER AXEL
Abstract: Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.
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公开(公告)号：IN1608DEN2015A
公开(公告)日：2015-07-03
申请号：IN1608DEN2015
申请日：2015-02-26
Applicant: CALIFORNIA INST OF TECHN
Inventor： MALIK IMRAN R , MADERO XIOMARA L , GARCIA ERIKA F , SCHERER AXEL
IPC: G01N21/17
Abstract: Structures and methods are described for optical detection of physical chemical and/or biological samples. An optical detection structure may include a LED source multiple filters and single or multiple sample areas. A detector may be used to record a fluorescence signal. The sample area may allow the introduction of removable cartridges.
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公开(公告)号：CA2897474A1
公开(公告)日：2014-07-31
申请号：CA2897474
申请日：2014-01-23
Applicant: CALIFORNIA INST OF TECHN
Inventor： RAJAGOPAL ADITYA , GOLDBERG MARK D , GARCIA ERIKA F , MADERO XIOMARA L , TOMBRELLO THOMAS A , SCHERER AXEL
Abstract: This disclosure provides methods, compositions and kits for the detection of a plurality of analytes in a sample. In some examples, this disclosure provides methods, compositions, and kits for detecting analytes, genetic variations, monitoring reaction process, and monitoring analyte-analyte interactions by measuring signals. In some examples, the presence of signals or changes in signals may be used to construct signal profiles which can be used to determine the presence or absence of analytes.
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