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公开(公告)号:WO0073413A2
公开(公告)日:2000-12-07
申请号:PCT/US0014740
申请日:2000-05-30
Applicant: CEPHEID
Inventor: TAYLOR MICHAEL T , BELGRADER PHILLIP , POURAHMADI FRAZAD , MCMILLAN WILLIAM A , CHANG RONALD , SAKAI STANLEY H , CHING JESUS , PETERSEN KURT E , NORTHRUP M ALLEN
IPC: C12M1/33 , B01L3/00 , B01L7/00 , C12M1/26 , C12N1/00 , G01N1/04 , G01N1/10 , G01N33/48 , C12M3/08
CPC classification number: B01L3/502 , B01L7/52 , B01L2200/10 , B01L2300/0654 , B01L2300/0681 , B01L2300/0809 , B01L2300/087 , B01L2400/0487 , B01L2400/0622 , B01L2400/0644 , C12N1/066 , C12N13/00 , Y10S435/81 , Y10S436/805 , Y10S436/806 , Y10S436/807 , Y10S436/809 , Y10S436/829 , Y10T137/87716 , Y10T137/88046 , Y10T436/255
Abstract: An apparatus for disrupting cells or viruses comprises a container having a chamber for holding the cells or viruses. The container includes at least one flexible wall defining the chamber. The apparatus also includes a transducer for impacting an external surface of the flexible wall to generate pressure waves in the chamber. The apparatus also includes a pressure source for increasing the pressure in the chamber. The pressurization of the chamber ensures effective coupling between the transducer and the flexible wall. The apparatus may also include beads in the chamber for rupturing the cells or viruses.
Abstract translation: 用于破坏细胞或病毒的装置包括具有用于保持细胞或病毒的室的容器。 容器包括限定腔室的至少一个柔性壁。 该装置还包括用于冲击柔性壁的外表面的换能器,以在腔室中产生压力波。 该装置还包括用于增加腔室中的压力的压力源。 室的加压确保换能器与柔性壁之间的有效耦合。 该装置还可以包括室中的珠子,用于破裂细胞或病毒。
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公开(公告)号:WO0073413A9
公开(公告)日:2002-01-24
申请号:PCT/US0014740
申请日:2000-05-30
Applicant: CEPHEID
Inventor: TAYLOR MICHAEL T , BELGRADER PHILLIP , POURAHMADI FRAZAD , MCMILLAN WILLIAM A , CHANG RONALD , SAKAI STANLEY H , CHING JESUS , PETERSEN KURT E , NORTHRUP M ALLEN
IPC: C12M1/33 , B01L3/00 , B01L7/00 , C12M1/26 , C12N1/00 , G01N1/04 , G01N1/10 , G01N33/48 , C12M3/08
CPC classification number: B01L3/502 , B01L7/52 , B01L2200/10 , B01L2300/0654 , B01L2300/0681 , B01L2300/0809 , B01L2300/087 , B01L2400/0487 , B01L2400/0622 , B01L2400/0644 , C12N1/066 , C12N13/00 , Y10S435/81 , Y10S436/805 , Y10S436/806 , Y10S436/807 , Y10S436/809 , Y10S436/829 , Y10T137/87716 , Y10T137/88046 , Y10T436/255
Abstract: An apparatus for disrupting cells or viruses comprises a container having a chamber for holding the cells or viruses. The container includes at least one flexible wall defining the chamber. The apparatus also includes a transducer for impacting an external surface of the flexible wall to generate pressure waves in the chamber. The apparatus also includes a pressure source for increasing the pressure in the chamber. The pressurization of the chamber ensures effective coupling between the transducer and the flexible wall. The apparatus may also include beads in the chamber for rupturing the cells or viruses.
Abstract translation: 用于破坏细胞或病毒的装置包括具有用于保持细胞或病毒的室的容器。 容器包括限定腔室的至少一个柔性壁。 该装置还包括用于冲击柔性壁的外表面的换能器,以在腔室中产生压力波。 该装置还包括用于增加腔室中的压力的压力源。 室的加压确保换能器与柔性壁之间的有效耦合。 该装置还可以包括室中的珠子,用于破裂细胞或病毒。
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公开(公告)号:DE60022025T2
公开(公告)日:2006-06-29
申请号:DE60022025
申请日:2000-05-30
Applicant: CEPHEID SUNNYVALE
Inventor: TAYLOR T , BELGRADER PHILLIP , POURAHMADI FRAZAD , MCMILLAN A , CHANG RONALD , SAKAI H , CHING JESUS , PETERSEN E , NORTHRUP ALLEN
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公开(公告)号:AU5301000A
公开(公告)日:2000-12-18
申请号:AU5301000
申请日:2000-05-30
Applicant: CEPHEID
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公开(公告)号:DE60029582T3
公开(公告)日:2012-03-08
申请号:DE60029582
申请日:2000-05-30
Applicant: CEPHEID
Inventor: PETERSEN KURT , MCMILLAN WILLIAM , POURAHMADI FRAZAD , CHANG RONALD , DORITY DOUGLAS
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公开(公告)号:DK1181098T4
公开(公告)日:2011-09-26
申请号:DK00937894
申请日:2000-05-30
Applicant: CEPHEID
Inventor: PETERSEN KURT E , MCMILLAN WILLIAM A , POURAHMADI FRAZAD , CHANG RONALD , DORITY DOUGLAS B
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公开(公告)号:CA2373198A1
公开(公告)日:2000-12-07
申请号:CA2373198
申请日:2000-05-30
Applicant: CEPHEID
Inventor: DORITY DOUGLAS B , MCMILLAN WILLIAM A , POURAHMADI FRAZAD , CHANG RONALD , PETERSEN KURT E
IPC: G01N33/48 , B01J19/00 , B01J19/24 , B01L3/00 , B01L7/00 , C12M1/00 , C12M1/26 , G01N33/483 , G01N35/08
Abstract: A cartridge (20) for conducting a chemical reaction includes a body having a t least one flow path formed therein. The cartridge also includes a reaction vessel (40) extending from the body for holding a reaction mixture for chemical reaction and optical detection. The vessel (40) comprises a rigid frame defining the side walls of a reaction chamber. The frame includes at least one channel connecting the flow path to the chamber. The vessel also includes flexible films or sheets attached to opposite sides of the rigid frame to form opposing major walls of the chamber. In addition, at least two of the side walls are optically transmissive and angularly offset from each to permit real-time optical detection of analyte in the reaction chamber.
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公开(公告)号:CA2373249C
公开(公告)日:2011-08-02
申请号:CA2373249
申请日:2000-05-30
Applicant: CEPHEID
Inventor: TAYLOR MICHAEL T , BELGRADER PHILLIP , POURAHMADI FRAZAD , MCMILLAN WILLIAM A , CHANG RONALD , SAKAI STANLEY H , CHING JESUS , PETERSEN KURT E , NORTHRUP M ALLEN
IPC: C12M1/33 , C12M3/08 , B01L3/00 , B01L7/00 , C12M1/26 , C12N1/00 , G01N1/04 , G01N1/10 , G01N33/48
Abstract: An apparatus for disrupting cells or viruses comprises a container having a chamber for holding the cells or viruses. The container includes at least one flexible wall defining the chamber. The apparatus also includes a transducer for impacting an external surface of the flexible wall to generate pressure waves in the chamber. The apparatus also includes a pressure source for increasing the pressure in the chamber. The pressurization of the chamber ensures effective coupling between the transducer and the flexible wall. The apparatus may also include beads in the chamber for rupturing the cells or viruses.
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公开(公告)号:DE60029582D1
公开(公告)日:2006-09-07
申请号:DE60029582
申请日:2000-05-30
Applicant: CEPHEID
Inventor: PETERSEN E , MCMILLAN A , POURAHMADI FRAZAD , CHANG RONALD , DORITY B
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公开(公告)号:AU781122B2
公开(公告)日:2005-05-05
申请号:AU5300900
申请日:2000-05-30
Applicant: CEPHEID
Inventor: PETERSEN KURT E , MCMILLAN WILLIAM A , POURAHMADI FRAZAD , CHANG RONALD , DORITY DOUGLAS B
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