-
公开(公告)号:WO2019027468A1
公开(公告)日:2019-02-07
申请号:PCT/US2017/045436
申请日:2017-08-04
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: MYERS, Carl , BEGUM-GAFUR, Rehana , MILLER, Jeffrey Merl , MAKWANA, Ekta
Abstract: This application provides, among other things, novel aqueous biphasic oral care compositions comprising two distinct aqueous phases, useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with anionic polymers, e.g. that protect against erosion and staining, by addition of a stabilizing amount of a polyamine, e.g. lysine, and methods for making and using the same.
-
公开(公告)号:WO2017096000A1
公开(公告)日:2017-06-08
申请号:PCT/US2016/064349
申请日:2016-12-01
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: MYERS, Carl , BEGUM-GAFUR, Rehana
CPC classification number: A61K8/8164 , A61K8/39 , A61K8/41 , A61K8/416 , A61K8/44 , A61K8/463 , A61K8/8147 , A61K8/86 , A61Q11/00
Abstract: This application provides, among other things, novel aqueous oral care compositions useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with anionic polymers that protect against erosion and staining, by addition of a stabilizing amount of a polyamine, e.g., lysine, and methods for making and using the same.
Abstract translation: 本申请尤其提供了用于组合和递送不相容的成分的新型水性口腔护理组合物,例如用于递送有效量的阳离子抗菌剂与防止侵蚀的阴离子聚合物以及 通过加入稳定量的多胺例如赖氨酸染色,以及制备和使用它们的方法。 p>
-
公开(公告)号:WO2018119015A1
公开(公告)日:2018-06-28
申请号:PCT/US2017/067472
申请日:2017-12-20
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: REGE, Aarti , PRENCIPE, Michael , THOMSON, Paul , BEGUM-GAFUR, Rehana
Abstract: This invention relates to oral care compositions comprising zinc phosphate, a first source of stannous (e.g., stannous fluoride); and a second source of stannous, wherein the second source of stannous comprises stannous pyrophosphate, as well as to methods of using and of making these compositions.
-
公开(公告)号:WO2017223321A1
公开(公告)日:2017-12-28
申请号:PCT/US2017/038767
申请日:2017-06-22
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: THOMSON, Paul , DOGU, Nihal , RAJAH, Divino , DAEP, Carlo , BEGUM-GAFUR, Rehana , PRENCIPE, Michael
Abstract: This invention relates to oral care compositions comprising a first source of zinc which is zinc citrate, a second source of zinc which is zinc oxide or zinc lactate, a stannous ion source, and a polyphosphate, as well as to methods of using and of making these compositions.
Abstract translation: 本发明涉及口腔护理组合物,其包含作为柠檬酸锌的第一锌源,作为氧化锌或乳酸锌的第二锌源,亚锡离子源和多磷酸盐 至于使用和制造这些组合物的方法。 p>
-
公开(公告)号:WO2020139629A1
公开(公告)日:2020-07-02
申请号:PCT/US2019/066903
申请日:2019-12-17
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: SARMA, Tulika , BEGUM-GAFUR, Rehana
Abstract: Methods for visualizing oral biofilm growth and methods for identifying compounds that modulate biofilm growth are provided. Biofilm samples are stained with fluorescent dyes and viewed with a confocal laser scanning microscope. Biofilm samples are in a container with a cover slip configured for viewing the biofilm sample with the confocal laser scanning microscope and the coverslip has a thickness variation of 0.02 mm or less.
-
公开(公告)号:WO2018031357A1
公开(公告)日:2018-02-15
申请号:PCT/US2017/045214
申请日:2017-08-03
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: MYERS, Carl , BEGUM-GAFUR, Rehana , DUCHEMIN, Katelyn , MUIR, Melissa
Abstract: This application provides, among other things, novel aqueous oral care compositions useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with short chain polyphosphate salts that protect against erosion and staining, by addition of a stabilizing amount of an anionic surfactant and methods for making and using the same.
Abstract translation: 本申请特别提供了用于组合和递送不相容的成分的新型水性口腔护理组合物,例如用于递送有效量的阳离子抗菌剂与短链多磷酸盐组合以防止 侵蚀和染色,通过加入稳定量的阴离子表面活性剂及其制备和使用方法。 p>
-
公开(公告)号:WO2015069301A1
公开(公告)日:2015-05-14
申请号:PCT/US2013/069514
申请日:2013-11-11
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: LEWUS, Catherine , DU-THUMM, Laurence D. , BEGUM-GAFUR, Rehana , SMITH-WEBSTER, Kimdra , VANDEVEN, Mark
CPC classification number: A61K8/368 , A61K2800/524 , A61K2800/5922 , A61Q11/00 , A61Q15/00 , A61Q19/10
Abstract: Provided herein is a cost-effective and potent preservative system for a composition comprising a salicylate salt and a benzoate salt in an amount of from 0.2 weight % to 0.5 weight % by total weight of the composition and in a molar ratio of salicylate to benzoate of 1:6 to 1:1.2, wherein the composition has a pH of 5 or less. Further provided herein is a method of using a combination of a salicylate salt and a benzoate salt in a preservative system in a composition, and a method of preserving a composition.
Abstract translation: 本文提供了一种用于组合物的成本有效和有效的防腐剂体系,其包含水杨酸盐和苯甲酸盐,其量为组合物总重量的0.2重量%至0.5重量%,水杨酸盐与苯甲酸酯的摩尔比为 1:6〜1:1.2,其中,所述组合物的pH为5以下。 本文还提供了在组合物中在防腐剂体系中使用水杨酸盐和苯甲酸盐的组合的方法以及保存组合物的方法。
-
公开(公告)号:EP3364939A1
公开(公告)日:2018-08-29
申请号:EP16813195.1
申请日:2016-12-01
Applicant: Colgate-Palmolive Company
Inventor: MYERS, Carl , BEGUM-GAFUR, Rehana
CPC classification number: A61K8/8164 , A61K8/39 , A61K8/41 , A61K8/416 , A61K8/43 , A61K8/44 , A61K8/463 , A61K8/8147 , A61K8/86 , A61K8/90 , A61K2800/5422 , A61Q11/00
Abstract: This application provides, among other things, novel aqueous oral care compositions useful for combining and delivering poorly compatible ingredients, for example to deliver effective levels of cationic antibacterial agents in combination with anionic polymers that protect against erosion and staining, by addition of a stabilizing amount of a polyamine, e.g., lysine, and methods for making and using the same.
-
公开(公告)号:EP3626225A1
公开(公告)日:2020-03-25
申请号:EP19202688.8
申请日:2013-11-11
Applicant: Colgate-Palmolive Company
Inventor: LEWUS, Catherine , DU-THUMM, Laurence , BEGUM-GAFUR, Rehana , SMITH-WEBSTER, Kimdra , VANDEVEN, Mark
Abstract: Provided herein is a cost-effective and potent preservative system for a composition comprising a salicylate salt and a benzoate salt in an amount of from 0.2 weight % to 0.5 weight % by total weight of the composition and in a molar ratio of salicylate to benzoate of 1:6 to 1:1.2, wherein the composition has a pH of 5 or less. Further provided herein is a method of using a combination of a salicylate salt and a benzoate salt in a preservative system in a composition, and a method of preserving a composition.
-
公开(公告)号:EP3068369A1
公开(公告)日:2016-09-21
申请号:EP13795393.1
申请日:2013-11-11
Applicant: Colgate-Palmolive Company
Inventor: LEWUS, Catherine , DU-THUMM, Laurence D. , BEGUM-GAFUR, Rehana , SMITH-WEBSTER, Kimdra , VANDEVEN, Mark
CPC classification number: A61K8/368 , A61K2800/524 , A61K2800/5922 , A61Q11/00 , A61Q15/00 , A61Q19/10
Abstract: Provided herein is a cost-effective and potent preservative system for a composition comprising a salicylate salt and a benzoate salt in an amount of from 0.2 weight % to 0.5 weight % by total weight of the composition and in a molar ratio of salicylate to benzoate of 1:6 to 1:1.2, wherein the composition has a pH of 5 or less. Further provided herein is a method of using a combination of a salicylate salt and a benzoate salt in a preservative system in a composition, and a method of preserving a composition.
Abstract translation: 本文提供了用于包含水杨酸盐和苯甲酸盐的组合物的成本有效且有效的防腐剂体系,其含量为组合物总重量的0.2重量%至0.5重量%,并且水杨酸盐与苯甲酸盐的摩尔比为 1:6至1:1.2,其中所述组合物具有5或更小的pH。 本文进一步提供了在组合物中使用水杨酸盐和苯甲酸盐在防腐剂体系中的组合的方法,以及保存组合物的方法。
-
-
-
-
-
-
-
-
-