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公开(公告)号:WO2018118161A1
公开(公告)日:2018-06-28
申请号:PCT/US2017/052183
申请日:2017-09-19
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: REGE, Aarti , PRENCIPE, Michael , THOMSON, Paul
Abstract: This invention relates to oral care compositions comprising a zinc source comprising zinc oxide and zinc citrate; a stannous source comprising stannous pyrophosphate; a fluoride ion source comprising sodium fluoride; and an organic buffer, as well as to methods of using and of making these compositions.
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公开(公告)号:WO2017003856A1
公开(公告)日:2017-01-05
申请号:PCT/US2016/039226
申请日:2016-06-24
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: THOMSON, Paul , DOGU, Nihal , PRENCIPE, Michael , RUSSO, Amy , STETTLER, Hans , MORGAN, Andre Michelle
CPC classification number: A61K8/44 , A61K8/21 , A61K8/25 , A61K8/27 , A61K8/345 , A61K8/362 , A61K8/365 , A61K2800/28 , A61K2800/92 , A61Q11/00
Abstract: This invention relates to oral care compositions comprising a basic amino acid in free or salt from (e.g., free form arginine); zinc oxide and zinc citrate; and a fluoride source comprising stannous fluoride.
Abstract translation: 本发明涉及包含游离或盐的碱性氨基酸(例如游离形式的精氨酸)的口腔护理组合物; 氧化锌和柠檬酸锌; 和含氟化亚锡的氟化物源。
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公开(公告)号:WO2020214311A1
公开(公告)日:2020-10-22
申请号:PCT/US2020/023068
申请日:2020-03-17
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: HAO, Zhigang , THOMSON, Paul , PAN, Long , BRINZARI, Tatiana , XU, Guofeng , LEITE, Sergio , WANG, Yu
Abstract: Disclosed herein are improved methods for the synthesis of stannous pyrophosphate, as well as improved methods for the manufacture of oral care compositions comprising stannous pyrophosphate.
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公开(公告)号:WO2020131401A1
公开(公告)日:2020-06-25
申请号:PCT/US2019/064610
申请日:2019-12-05
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: EVANS, Lauren , PATEL, Neeta Atul , PAPPAS, Iraklis , HU, Zhichao , THOMSON, Paul
Abstract: This invention relates to dentifrice compositions comprising a high level of sodium bicarbonate and a stannous ion source, as well as to methods of using these compositions. Optionally, the dentifrice compositions further comprise zinc oxide.
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公开(公告)号:WO2019117890A1
公开(公告)日:2019-06-20
申请号:PCT/US2017/066081
申请日:2017-12-13
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: MOHAMMED, Evelyn , FAROOQ, Amjad , VOGT, Robert , THOMSON, Paul , MIRAJKAR, Yelloji-Rao K. , YEUNG, Victoria
CPC classification number: A61K8/25 , A61K8/11 , A61K8/731 , A61K8/8147 , A61K8/927 , A61K2800/412 , A61Q11/00
Abstract: Disclosed herein is a composition comprising a pH-sensitive microcapsule comprising (1) a shell wall comprising at least one polymer chosen from cellulose derivatives and acrylate derivatives, and at least one structuring agent chosen from shellac, ethyl cellulose, and fumed silica, and (2) at least one functional ingredient encapsulated inside the shell wall; and a carrier having a pH of less than about 7. Further disclosed herein are methods of making a composition comprising a pH-sensitive microcapsule.
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公开(公告)号:WO2021195590A1
公开(公告)日:2021-09-30
申请号:PCT/US2021/024524
申请日:2021-03-26
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: DAEP, Carlo , TRIVEDI, Harsh Mahendra , THOMSON, Paul
IPC: A61K8/21 , A61K8/27 , A61K8/41 , A61Q11/00 , A61K8/44 , A61K8/20 , A61K8/365 , A61K8/43 , A61Q11/02
Abstract: This invention relates to oral care compositions comprising guanidine, zinc citrate and zinc oxide, and a fluoride source, as well as to methods of using and of making these compositions.
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公开(公告)号:WO2020263387A1
公开(公告)日:2020-12-30
申请号:PCT/US2020/028953
申请日:2020-04-20
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: THOMSON, Paul , MAKWANA, Ekta , D'AMBROGIO, Robert , DOGU, Nihal
Abstract: This invention relates to a gum system for oral care compositions, where the oral care composition comprises a first stannous ion source, a second stannous ion source, wherein the second stannous ion comprises stannous pyrophosphate, and a source of zinc selected from zinc oxide, zinc citrate, zinc lactate, and combinations thereof, and a gum system comprising hydroxyethylcellulose (HEC) and carrageenan, as well as to methods of using and making these compositions.
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公开(公告)号:WO2021127699A1
公开(公告)日:2021-06-24
申请号:PCT/US2020/070926
申请日:2020-12-18
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: THOMSON, Paul , D'AMBROGIO, Robert , DENIS, Jean , XU, Guofeng
Abstract: The invention relates to oral care compositions comprising a first stannous ion source, a second stannous ion source, wherein the second stannous ion comprises stannous pyrophosphate, and a source of zinc selected from zinc oxide, zinc citrate, zinc lactate, and combinations thereof, and a humectant system comprising glycerin and sorbitol, and a thickening system, as well as to methods of using and making these compositions.
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公开(公告)号:WO2018119015A1
公开(公告)日:2018-06-28
申请号:PCT/US2017/067472
申请日:2017-12-20
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: REGE, Aarti , PRENCIPE, Michael , THOMSON, Paul , BEGUM-GAFUR, Rehana
Abstract: This invention relates to oral care compositions comprising zinc phosphate, a first source of stannous (e.g., stannous fluoride); and a second source of stannous, wherein the second source of stannous comprises stannous pyrophosphate, as well as to methods of using and of making these compositions.
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公开(公告)号:WO2017223321A1
公开(公告)日:2017-12-28
申请号:PCT/US2017/038767
申请日:2017-06-22
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: THOMSON, Paul , DOGU, Nihal , RAJAH, Divino , DAEP, Carlo , BEGUM-GAFUR, Rehana , PRENCIPE, Michael
Abstract: This invention relates to oral care compositions comprising a first source of zinc which is zinc citrate, a second source of zinc which is zinc oxide or zinc lactate, a stannous ion source, and a polyphosphate, as well as to methods of using and of making these compositions.
Abstract translation: 本发明涉及口腔护理组合物,其包含作为柠檬酸锌的第一锌源,作为氧化锌或乳酸锌的第二锌源,亚锡离子源和多磷酸盐 至于使用和制造这些组合物的方法。 p>
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