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公开(公告)号:WO2022198013A1
公开(公告)日:2022-09-22
申请号:PCT/US2022/020898
申请日:2022-03-18
Inventor: GURUMURTHY, Bhuvana , WU, Donghui , FITZGERALD, Michael , WONG, David
IPC: C12Q1/6883
Abstract: The present invention describes a method for the detection and monitoring of xerostomia in a subject using biomarkers.
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公开(公告)号:WO2021127674A1
公开(公告)日:2021-06-24
申请号:PCT/US2020/070830
申请日:2020-11-30
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: HAMMADI, Salima , TRIVEDI, Harsh Mahendra , MARTINETTI, Melissa , SURIANO, David , FITZGERALD, Michael , XU, Yun , POTNIS, Shashank , SAMBANTHAMOORTHY, Karthik
Abstract: Described herein are oral care compositions comprising - in relevant part - an effective amount of inulin. Methods of making and using these compositions are also described.
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公开(公告)号:WO2019014109A1
公开(公告)日:2019-01-17
申请号:PCT/US2018/041263
申请日:2018-07-09
Applicant: COLGATE-PALMOLIVE COMPANY
IPC: A61B5/00
Abstract: An oral care evaluation system may include: a light source (103) configured to emit a spectrum of light which induces fluorescence in an organic compound, the light source illuminating soft oral tissue within an oral cavity; an image sensor (105) receiving light generated by fluorescence of the organic compound on the soft oral tissue, the image sensor generating image data for an image of the oral tissue, the image comprising a plurality of pixels; and an image processor (109) receiving the image data from the image sensor and programmed to evaluate oral hygiene of the soft oral tissue by assessing an attribute of each pixel in the image.
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公开(公告)号:WO2015195117A1
公开(公告)日:2015-12-23
申请号:PCT/US2014/042947
申请日:2014-06-18
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: FITZGERALD, Michael , CONVERY, Joseph , MANUS, Lisa , TRIVEDI, Harsh
IPC: C07F3/00
CPC classification number: C07F3/06 , C07B2200/13 , C07F3/003
Abstract: The disclosure provides an improved synthesis for a zinc-lysine complex having the formula [Zn(C 6 H 14 N 2 O 2 ) 2 Cl] + Cl - , in which a zinc compound selected from ZnO and ZnCl 2 , is reacted with a lysine compound selected from lysine and lysine•HCl, in aqueous acid. The disclosure also provides oral care and personal care compositions comprising the complex prepared by the synthesis, and methods of using these complexes and compositions.
Abstract translation: 本公开提供了具有式[Zn(C 6 H 14 N 2 O 2)2 Cl] + Cl-的锌 - 赖氨酸复合物的改进合成,其中选自ZnO和ZnCl 2的锌化合物与选自赖氨酸和赖氨酸的赖氨酸化合物反应•HCl ,在酸性水溶液中。 本公开还提供了包含通过合成制备的络合物的口腔护理和个人护理组合物,以及使用这些复合物和组合物的方法。
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公开(公告)号:WO2011079001A2
公开(公告)日:2011-06-30
申请号:PCT/US2010/060634
申请日:2010-12-16
Applicant: COLGATE-PALMOLIVE COMPANY , PAN, Long , WU, Donghui , KILPATRICK-LIVERMAN, LaTonya , EIBLING, Matthew J. , FITZGERALD, Michael , PAPPAS, Iraklis
Inventor: PAN, Long , WU, Donghui , KILPATRICK-LIVERMAN, LaTonya , EIBLING, Matthew J. , FITZGERALD, Michael , PAPPAS, Iraklis
IPC: A61Q15/00
CPC classification number: A61K8/416 , A61K8/26 , A61K8/42 , A61K8/44 , A61K2800/31 , A61K2800/58 , A61Q15/00
Abstract: An anhydrous liquid antiperspirant/deodorant composition comprising a carrier comprising a cation and/or zwitterion and a hydrogen bond donor, wherein an amount of carrier is greater than an amount of any other material in the composition, and an antiperspirant active. This represents a new delivery form for antiperspirant actives and/or deodorant actives.
Abstract translation: 一种无水液体止汗剂/除臭剂组合物,其包含载体,其包含阳离子和/或两性离子和氢键供体,其中载体的量大于组合物中任何其它材料的量和止汗活性剂。 这代表了止汗活性物质和/或除臭活性物质的新的交付形式。
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公开(公告)号:WO2022178106A1
公开(公告)日:2022-08-25
申请号:PCT/US2022/016767
申请日:2022-02-17
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: HU, Zhichao , FITZGERALD, Michael , PAPPAS, Iraklis , HAGHSHENAS, Keeyan , QIAN-PENA, Junfang, Katy , WOLF, John , ZENG, Lingfei , CLARK, Teressa , JOYCE, Jason , WIREMAN, Evan
Abstract: A system, apparatus, and/or method is disclosed for – inter alia – producing a product. One or more financial characteristics relating to one or more sample products may be received. For each of the sample products, a value for each of one or more respective properties of the sample product may be received. The received values of the one or more respective properties of the sample products, the one or more received financial characteristics relating to the sample products, and a desired financial characteristic for a potential product may be input into the machine learning model. A value for each of the one or more respective properties for the potential product may be determined based on the desired financial characteristic for the potential product. A product having the determined value for each of the one or more respective properties for the potential product may be produced.
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公开(公告)号:WO2019125912A1
公开(公告)日:2019-06-27
申请号:PCT/US2018/065500
申请日:2018-12-13
Applicant: COLGATE-PALMOLIVE COMPANY , NORTHWESTERN UNIVERSITY
IPC: G01N23/087
CPC classification number: G01N23/083 , G01N21/8914 , G01N21/94 , G01N23/087 , G01N2021/8918
Abstract: The disclosure contains a method of quantifying and/or evaluating metal ions in a dentifrice, wherein the method comprises subjecting the dentifrice to X-ray absorption spectroscopy (XAS), and wherein the XAS is used to measure and/or evaluate the metal ions in the dentifrice. Also disclosed are methods of selecting and screening for dentifrices based upon the evaluation and quantification of their metal ion content.
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8.
公开(公告)号:WO2021025661A1
公开(公告)日:2021-02-11
申请号:PCT/US2019/044783
申请日:2019-08-02
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: WU, Donghui , FITZGERALD, Michael
Abstract: A system for detecting blood in an oral cavity during toothbrushing. The system may include a toothbrush having a sensor that is configured to emit first light at a first wavelength and second light at a second wavelength, receive reflected portions of the first and second light, and generate a first signal indicative of a first intensity of the reflected portion of the first light and a second signal indicative of a second intensity of the reflected portion of the second light. The system may include a processor operably coupled to the sensor, the processor being configured to receive the first and second signals and calculate a ratio of the first intensity to the second intensity to determine whether hemoglobin/blood is present in the oral cavity. The processor may be a part of the toothbrush or a part of a portable electronic device such as a smart phone.
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公开(公告)号:WO2019232461A1
公开(公告)日:2019-12-05
申请号:PCT/US2019/035032
申请日:2019-05-31
Inventor: ANSARI, Shamim , LIN, Zhongtian , SUI, Jianye , JAVANMARD, Mehdi , WU, Donghui , FITZGERALD, Michael
IPC: G01N33/543
Abstract: Described herein are methods, systems and devices for rapidly detecting biomarkers in a biological sample.
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公开(公告)号:WO2017117500A1
公开(公告)日:2017-07-06
申请号:PCT/US2016/069419
申请日:2016-12-30
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: DAEP, Carlo , FITZGERALD, Michael , MAKWANA, Ekta , HILLIARD, Peter , ANSARI, Shamim , D'AMBROGIO, Robert
IPC: C01B33/12 , A61K6/00 , C01B33/149
CPC classification number: C01B33/149 , A61K6/0038 , C08L1/00
Abstract: Disclosed herein is mucin-coated silica, compositions comprising the same, and methods of promoting the aggregation and/or clearance of oral bacteria using such compositions.
Abstract translation: 本文公开了粘蛋白包被的二氧化硅,包含其的组合物,以及使用这种组合物促进口腔细菌聚集和/或清除的方法。 p>
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