公开(公告)号：WO2017223181A1

公开(公告)日：2017-12-28

申请号：PCT/US2017/038508

申请日：2017-06-21

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： YANG, Ying ,  CHEN, Dandan ,  D'AMBROGIO, Robert ,  THOMSON, Paul ,  TRIVEDI, Harsh Mahendra ,  PRENCIPE, Michael ,  MASTERS, James Gerard ,  JARACZ, Stanislav

IPC: A61K8/27 ,  A61K8/34 ,  A61K8/35 ,  A61K8/365 ,  A61Q11/00 ,  A61K8/21 ,  A61Q17/00

Abstract: This invention relates to oral care compositions comprising zingerone, bisabolol, a stannous ion source, zinc oxide, and zinc citrate, as well as to methods of using and of making these compositions.

Abstract translation: 本发明涉及包含姜油酮，红没药醇，亚锡离子源，氧化锌和柠檬酸锌的口腔护理组合物，以及使用和制备这些组合物的方法。

公开(公告)号：WO2021097483A1

公开(公告)日：2021-05-20

申请号：PCT/US2020/070772

申请日：2020-11-12

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： ARORA, Payal ,  TRIVEDI, Harsh Mahendra ,  MASTERS, James G. ,  AHMED, Rabab ,  MELLO, Sarita ,  LEITE, Sergio

IPC: A61K8/36 ,  A61K8/67 ,  A61Q11/00

Abstract: Described herein are oral care compositions comprising vitamin D, or a derivative thereof; an alkanoic acid of formula R-COOH or an alkali metal salt thereof, wherein R is a C1 to C13 hydrocarbyl group; and an orally acceptable carrier. Methods of making and using same are also described.

公开(公告)号：WO2021092613A1

公开(公告)日：2021-05-14

申请号：PCT/US2020/070717

申请日：2020-10-29

Applicant: COLGATE-PALMOLIVE COMPANY ,  REGENTS OF THE UNIVERSITY OF MICHIGAN

Inventor： DAEP, Carlo ,  HINES, Deon ,  TRIVEDI, Harsh Mahendra ,  MASTERS, James G. ,  KILPATRICK-LIVERMAN, LaTonya ,  RINAUDI MARRON, Luciana ,  ZAIDEL, Lynette A. ,  RICKARD, Alexander ,  SAMARIAN, Derek ,  GICQUELAIS, Rachel ,  KRUSE, Gregory

IPC: A61K8/19 ,  A61K8/27 ,  A61K8/44 ,  A61Q11/00

Abstract: Described herein are methods of treating biofilm (e.g. modifying surface topography, reducing thickness or reducing biovolume) and compositions and apparatus for use in carrying out such methods.

公开(公告)号：WO2020139598A1

公开(公告)日：2020-07-02

申请号：PCT/US2019/066501

申请日：2019-12-16

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： DAEP, Carlo ,  MAKWANA, Ekta ,  ZAIDEL, Lynette ,  YANG, Ying ,  TRIVEDI, Harsh Mahendra

IPC: A61K9/00 ,  A61K47/02 ,  A61K47/18 ,  A61K8/27 ,  A61K8/44 ,  A61P1/02 ,  A61P9/08 ,  A61P31/04 ,  A61Q11/00

Abstract: The present disclosure relates to oral care compositions providing oral and/or systemic benefits. In some embodiments, the oral care compositions of the present disclosure comprise arginine or a salt thereof, and one or more zinc ion sources (e.g., zinc oxide and zinc citrate), as well as to methods of making these compositions.

公开(公告)号：WO2019014109A1

公开(公告)日：2019-01-17

申请号：PCT/US2018/041263

申请日：2018-07-09

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： PACELLI, Michael ,  SUBHASH, Hrebesh Molly ,  FITZGERALD, Michael ,  TRIVEDI, Harsh Mahendra

IPC: A61B5/00

Abstract: An oral care evaluation system may include: a light source (103) configured to emit a spectrum of light which induces fluorescence in an organic compound, the light source illuminating soft oral tissue within an oral cavity; an image sensor (105) receiving light generated by fluorescence of the organic compound on the soft oral tissue, the image sensor generating image data for an image of the oral tissue, the image comprising a plurality of pixels; and an image processor (109) receiving the image data from the image sensor and programmed to evaluate oral hygiene of the soft oral tissue by assessing an attribute of each pixel in the image.

公开(公告)号：WO2021134097A1

公开(公告)日：2021-07-01

申请号：PCT/US2020/070922

申请日：2020-12-17

Applicant: COLGATE-PALMOLIVE COMPANY ,  THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL

Inventor： ARORA, Payal ,  TRIVEDI, Harsh Mahendra ,  HAO, Zhigang ,  THOMSON, Paul ,  MANDHARE, Manish ,  WANG, Yu ,  CHENG, Chi-Yuan ,  PAN, Long ,  BARROS, Silvana

IPC: A61K8/9794 ,  A61K8/35 ,  A61Q11/00 ,  A61Q17/00

Abstract: Described herein are methods for improving or maintaining the barrier integrity of gingival tissue comprising administering an oral care composition comprising a curcuminoid, to the oral cavity of a subject in need thereof.

公开(公告)号：WO2021134096A1

公开(公告)日：2021-07-01

申请号：PCT/US2020/070921

申请日：2020-12-17

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： ARORA, Payal ,  TRIVEDI, Harsh Mahendra ,  HAO, Zhigang ,  THOMSON, Paul ,  MANDHARE, Manish ,  WANG, Yu ,  CHENG, Chi-Yuan ,  PAN, Long

IPC: A61K8/9794 ,  A61K8/35 ,  A61K8/46 ,  A61Q11/00 ,  A61Q17/00 ,  A61K8/463 ,  A61Q17/005

Abstract: Described herein are - inter alia - complexes comprising a curcuminoid; and an anionic surfactant. Methods of making and using same are also described.

公开(公告)号：WO2017223169A1

公开(公告)日：2017-12-28

申请号：PCT/US2017/038487

申请日：2017-06-21

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： CHEN, Dandan ,  YANG, Ying ,  D'AMBROGIO, Robert ,  THOMSON, Paul ,  TRIVEDI, Harsh Mahendra ,  PRENCIPE, Michael ,  MASTERS, James Gerard ,  JARACZ, Stanislav

IPC: A61K8/27 ,  A61K8/35 ,  A61Q11/00 ,  A61K8/19

Abstract: This invention relates to oral care compositions comprising zingerone, a stannous ion source, zinc oxide, and zinc citrate, as well as to methods of using and of making these compositions.

Abstract translation: 本发明涉及包含姜油酮，亚锡离子源，氧化锌和柠檬酸锌的口腔护理组合物，以及使用和制造这些组合物的方法。

公开(公告)号：WO2017116977A1

公开(公告)日：2017-07-06

申请号：PCT/US2016/068286

申请日：2016-12-22

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： JOHANSSON, Patrik ,  GATZEMEYER, John ,  TRIVEDI, Harsh Mahendra ,  MASTERS, James

IPC: A61C19/06

CPC classification number: A61C19/066 ,  A61C19/06 ,  A61C19/063 ,  A61K8/23 ,  A61K8/24 ,  A61K8/33 ,  A61N1/0548 ,  A61Q11/00 ,  A61Q11/02 ,  C25B1/00 ,  C25B9/06

Abstract: In some embodiments, an oral care device includes a flexible base substrate, a power source disposed on the base substrate, and first and second electrodes electrically connected to the power source. Also disclosed are methods of using the same, for example, for whitening the teeth or for treating other conditions in the oral cavity.

Abstract translation: 在一些实施例中，口腔护理装置包括柔性基础基底，设置在基础基底上的电源以及电连接到电源的第一和第二电极。 还公开了使用它们的方法，例如用于美白牙齿或用于治疗口腔中的其他病症。

公开(公告)号：WO2021203132A1

公开(公告)日：2021-10-07

申请号：PCT/US2021/070338

申请日：2021-03-30

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： YANG, Ying ,  MASTERS, James ,  TRIVEDI, Harsh Mahendra ,  SARMA, Tulika

IPC: A61K31/198 ,  A61K31/401 ,  A61K31/405 ,  A61K33/16 ,  A61K33/30 ,  A61P1/02 ,  A61P43/00 ,  A61K8/21 ,  A61K8/27 ,  A61K8/44 ,  A61K8/58 ,  A61Q11/00

Abstract: Method of improving tissue integrity of tissue that functions as a barrier are provided. Method of protecting and maintaining tissue integrity of tissue that functions as a barrier are provided. Method of repairing damage to tissue that functions as a barrier, and to restoring and improving function of such damaged tissue are provided. Methods of improving, maintaining, protecting, repairing and/or restoring the integrity of tissue which functions as a barrier and repair of damage to and healing of wounds to such tissue improves, maintains, protects, repairs and restores immunity. The methods comprising contacting the tissue with an effective amount of a composition comprising one or more sources of zinc ions such as zinc oxide, zinc citrate, or combination thereof zinc oxide and zinc citrate, and optionally further comprising arginine and/or one or more neutral amino acids.