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公开(公告)号：WO2011075662A2
公开(公告)日：2011-06-23
申请号：PCT/US2010/061069
申请日：2010-12-17
Applicant: COLGATE-PALMOLIVE COMPANY , SHIMOHIRAO, Nilza , YAMANE, Odete Tieko , CORREIA, Abel , COSTA, Katrin , UTIMA, Enzo , DAVID, Andre S.
Inventor： SHIMOHIRAO, Nilza , YAMANE, Odete Tieko , CORREIA, Abel , COSTA, Katrin , UTIMA, Enzo , DAVID, Andre S.
IPC: A61K8/43
CPC classification number: A61K8/43 , A61K8/19 , A61K2800/524 , A61Q11/00
Abstract: Biguanide-preserved precipitated calcium carbonate oral care compositions and methods of manufacture thereof are disclosed.
Abstract translation: 公开了双胍保存的沉淀碳酸钙口腔护理组合物及其制造方法。
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公开(公告)号：WO2022032119A1
公开(公告)日：2022-02-10
申请号：PCT/US2021/044978
申请日：2021-08-06
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： MOURAO, Marcella , UTIMA, Enzo , CINQUETTI, Tatiana
Abstract: Disclosed herein are improved oral care formulations comprising precipitated calcium carbonate (PCC) and synergistic preservative combinations selected. Methods of making and using the compositions are also provided.
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公开(公告)号：WO2021179014A1
公开(公告)日：2021-09-10
申请号：PCT/US2021/070241
申请日：2021-03-05
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： UTIMA, Enzo , PRAT, Erico , CAZES, Abraham , FOCASSIO, Paulo , NAKAJIMA, Murilo Nogueira
Abstract: The present invention provides calcium carbonate-based oral care compositions, in particular toothpastes comprising a thickening system comprising 0.2-0.5 wt.% xanthan gum and 0.2-0.5 wt.% synthetic poly acrylic acid polymer, as well as methods of using these compositions.
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公开(公告)号：WO2020205238A1
公开(公告)日：2020-10-08
申请号：PCT/US2020/023244
申请日：2020-03-18
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： UTIMA, Enzo , CAZES, Abraham , PRAT, Erico
Abstract: This invention relates to high-water oral care compositions comprising a basic amino acid or salt thereof, together with a precipitated calcium carbonate, glycerol, and to methods of using and of making these compositions.
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公开(公告)号：WO2022251439A1
公开(公告)日：2022-12-01
申请号：PCT/US2022/031052
申请日：2022-05-26
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： NAKAJIMA, Murilo, Nogueira , TANG, Saide , UTIMA, Enzo , XU, Guofeng , PIMENTA, Paloma
Abstract: This application provides, among other things, oral care compositions where the addition of a stabilizing amount of a nonionic gelling and thickening agent, (e.g., hydroxyethyl cellulose (HEC)) and an effective amount of a zwitterionic surfactant (e.g., a betaine zwitterionic surfactant) (e.g., cocamidopropyl betaine), to formulations comprising a bisbiguanide (e.g., chlorhexidine (CHX)) agent, and optionally an effective amount of abrasive silica, allows for proper structure and consistency to the formulation and to allow it to be used as a gel or a toothpaste to facility delivery of chlorhexidine, among other actives, to the teeth or gums with acceptable stability and foaming.
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Patent Agency Ranking
公开(公告)号：WO2022251438A1
公开(公告)日：2022-12-01
申请号：PCT/US2022/031051
申请日：2022-05-26
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： NAKAJIMA, Murilo, Nogueira , TANG, Saide , WON, Betty , UTIMA, Enzo , XU, Guofeng , PIMENTA, Paloma , MELLO, Sarita , MUIR, Melissa
Abstract: This application provides, among other things, oral care compositions where the addition of a stabilizing amount of a nonionic gelling and thickening agent, (e.g., hydroxyethyl cellulose (HEC)), to formulations comprising a bisbiguanidine (e.g., chlorhexidine (CHX)) agent allows for proper structure and consistency to the formulation and to allow it to be used as a gel or a toothpaste to facility delivery of chlorhexidine, among other actives, to the teeth or gums.
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公开(公告)号：WO2018156545A1
公开(公告)日：2018-08-30
申请号：PCT/US2018/018896
申请日：2018-02-21
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： UTIMA, Enzo , CINQUETTI, Tatiana , CORREA, Fernanda , FOCASSIO, Paulo , PEDROSO, Debora
Abstract: Disclosed herein are improved oral care formulations comprising precipitated calcium carbonate (PCC) and preservative combinations selected from the group consisting of i) phenethyl alcohol and caprylyl glycol, and ii) benzyl alcohol and caprylyl glycol. Methods of making and using the compositions are also provided.
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公开(公告)号：WO2015085151A1
公开(公告)日：2015-06-11
申请号：PCT/US2014/068753
申请日：2014-12-05
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： UTIMA, Enzo , PRAT, Erico , POTNIS, Shashank , KAMATH, Shridhara , SIRDESAI, Amit , MADHAVI, Rupali , VARTAK, Santosh , PLATA, Rolando
Abstract: A method of determining the viability of a gum for use in making a product has been achieved by (a) mixing a sample of the gum in a solvent comprising one or more hydroxy moiety containing solvent compound to form a solution with the gum; (b) measuring the viscosity of the solution and comparing against a predetermined target viscosity for a product; and (c) comparing the viscosity of the solution and the predetermined target viscosity and discarding gum which is outside the predetermined target viscosity; and (d) using the gum which has a viscosity within the predetermined target to prepare a product; wherein another hydroxy moiety containing solvent is used if water is used as a solvent. Also described are compositions comprising the gum and solvent comprising one or more hydroxy moiety.
Abstract translation: 通过（a）将胶体样品在包含一种或多种含羟基部分的溶剂化合物的溶剂中混合以形成与胶的溶液，来实现确定用于制备产品的口香糖生存力的方法; （b）测量溶液的粘度并与产品的预定目标粘度进行比较; 和（c）比较所述溶液的粘度和所述预定目标粘度和所述预定目标粘度之外的弃胶的比例; 和（d）使用粘度在预定目标内的胶制备产品; 如果使用水作为溶剂，则使用另外含羟基部分的溶剂。 还描述了包含口香糖和包含一个或多个羟基部分的溶剂的组合物。
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公开(公告)号：EP3930672A1
公开(公告)日：2022-01-05
申请号：EP20719264.2
申请日：2020-03-18
Applicant: Colgate-Palmolive Company
Inventor： UTIMA, Enzo , CAZES, Abraham , PRAT, Erico
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公开(公告)号：EP4199894A1
公开(公告)日：2023-06-28
申请号：EP22733790.4
申请日：2022-05-26
Applicant: Colgate-Palmolive Company
Inventor： NAKAJIMA, Murilo, Nogueira , TANG, Saide , UTIMA, Enzo , XU, Guofeng , PIMENTA, Paloma
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