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1.发明申请ESCHERICHIA COLI VARIETY PRODUCING L-THREONINE AND METHOD FOR FABRICATING THE SAME 审中-公开生产L-精油的ESCHERICHIA COLI VARIETY及其制造方法
公开(公告)号：WO2008075855A1
公开(公告)日：2008-06-26
申请号：PCT/KR2007/006531
申请日：2007-12-14
Applicant: CJ CHEILJEDANG CORPORATION , KOH, Eun Sung , SHIN, Soo An , LEE, Jin Ho , LEE, Keun Chul , PARK, Young Hoon
Inventor： KOH, Eun Sung , SHIN, Soo An , LEE, Jin Ho , LEE, Keun Chul , PARK, Young Hoon
CPC classification number: C12P13/08
Abstract: The present invention relates to a transformed microorganism having improved threonine productivity. More particularly, the present invention relates to a threonine-producing microorganism transformed with a vector comprising a gene encoding an rpoS protein, the amino acid sequence of which has leucine at position 33. The microorganism of the present invention can produce L-threonine in a high yield, thereby being used in medicinal, pharmaceutical, and feed industries, in particular, as an animal feed.
Abstract translation: 本发明涉及具有改善的苏氨酸生产力的转化微生物。 更具体地说，本发明涉及用包含编码rpoS蛋白的基因的载体转化的苏氨酸生成微生物，其氨基酸序列在第33位具有亮氨酸。本发明的微生物可以生产L-苏氨酸 高产量，因此用于药用，制药和饲料工业，特别是动物饲料中。
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Patent Agency Ranking2.发明申请
公开(公告)号：WO2012099396A3
公开(公告)日：2012-07-26
申请号：PCT/KR2012/000444
申请日：2012-01-18
Applicant: CJ CHEILJEDANG CORPORATION , LEE, Kwang Ho , LEE, Keun Chul , LEE, Seok Myung , HWANG, Young Bin
Inventor： LEE, Kwang Ho , LEE, Keun Chul , LEE, Seok Myung , HWANG, Young Bin
Abstract: The present invention provides a microorganism of the genus Escherichia having enhanced L-amino acid productivity, wherein the microorganism is transformed to have an enhanced NAD kinase activity and an inactivated activity of an enzyme having an amino acid sequence of SEQ ID NO. 2 encoded by tehB gene and a method for producing L-amino acids using the microorganism of the genus Escherichia.
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3.发明公开MICROORGANISM WITH IMPROVED L-THREONINE PRODUCTIVITY, AND METHOD FOR PRODUCING L-THREONINE BY USING SAME 审中-公开具有增强的L-苏氨酸生产力和方法是这样就产生L-苏氨酸的微生物
公开(公告)号：EP3144385A1
公开(公告)日：2017-03-22
申请号：EP15837846.3
申请日：2015-09-04
Applicant: Cj Cheiljedang Corporation
Inventor： LEE, Ji Sun , LEE, Kwang Ho , KIM, Hyo Jin , LEE, Keun Chul , HWANG, Young Bin
Abstract: The present invention relates to a novel variant RNA polymerase sigma factor 70 (σ 70 ) polypeptide, a polynucleotide encoding the same, a microorganism containing the polypeptide, and a method for producing L-threonine by using the microorganism.
Abstract translation: 本发明涉及一种新颖的变体的RNA聚合酶σ因子70（A 70）的多肽，编码它的多核苷酸，含有微生物的多肽，以及用于通过使用该微生物生产L-苏氨酸的方法。
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4.发明授权A MICROORGANISM HAVING ENHANCED L-AMINO ACIDS PRODUCTIVITY AND PROCESS FOR PRODUCING L-AMINO ACIDS USING THE SAME 有权具有增强的L-氨基酸生产力的微生物和使用该氨基酸生产L-氨基酸的方法
公开(公告)号：EP2665809B1
公开(公告)日：2018-01-10
申请号：EP12736463.6
申请日：2012-01-18
Applicant: CJ Cheiljedang Corporation
Inventor： LEE, Kwang Ho , LEE, Keun Chul , LEE, Seok Myung , HWANG, Young Bin
CPC classification number: C12N15/70 , C07K14/245 , C12N9/1007 , C12N9/1205 , C12P13/04 , C12P13/08 , C12P13/227 , C12Y201/01 , C12Y207/01023
Abstract: A microorganism of the genus Escherichia having enhanced L-amino acid productivity, wherein the microorganism is transformed to have an enhanced NAD kinase activity and an inactivated activity of an enzyme having an amino acid sequence of SEQ ID NO: 2 encoded by tehB gene and a method for producing L-amino acids using the microorganism of the genus Escherichia.
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公开(公告)号：EP3144385B1
公开(公告)日：2020-08-12
申请号：EP15837846.3
申请日：2015-09-04
Applicant: CJ Cheiljedang Corporation
Inventor： LEE, Ji Sun , LEE, Kwang Ho , KIM, Hyo Jin , LEE, Keun Chul , HWANG, Young Bin
IPC: C12N9/12 , C12N15/54 , C12P13/08 , C07K14/245
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6.发明公开A MICROORGANISM HAVING ENHANCED L-AMINO ACIDS PRODUCTIVITY AND PROCESS FOR PRODUCING L-AMINO ACIDS USING THE SAME 有权具有增强的L-氨基酸生产力和SO生产L-氨基酸的方法微生物
公开(公告)号：EP2665809A2
公开(公告)日：2013-11-27
申请号：EP12736463.6
申请日：2012-01-18
Applicant: CJ Cheiljedang Corporation
Inventor： LEE, Kwang Ho , LEE, Keun Chul , LEE, Seok Myung , HWANG, Young Bin
CPC classification number: C12N15/70 , C07K14/245 , C12N9/1007 , C12N9/1205 , C12P13/04 , C12P13/08 , C12P13/227 , C12Y201/01 , C12Y207/01023
Abstract: A microorganism of the genus Escherichia having enhanced L-amino acid productivity, wherein the microorganism is transformed to have an enhanced NAD kinase activity and an inactivated activity of an enzyme having an amino acid sequence of SEQ ID NO: 2 encoded by tehB gene and a method for producing L-amino acids using the microorganism of the genus Escherichia.
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