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公开(公告)号：JP2001261736A
公开(公告)日：2001-09-26
申请号：JP2001014810
申请日：2001-01-23
Applicant: DEGUSSA
Inventor： BURKHARDT OLAF , WOELTINGER JENS , BOMMARIUS ANDREAS , ALMENA PEREA JUAN JOSE DR , HENNIGES HANS , DRAUZ KARLHEINZ , KARAU ANDREAS , PHILIPPE JEAN-LOUIS , KRIMMER HANS-PETER , OEHME GUENTHER
IPC: B01J31/22 , B01J31/16 , B01J31/18 , B01J31/24 , C07B31/00 , C07B53/00 , C07B61/00 , C07C231/12 , C07C233/47 , C08F8/00 , C08F8/30 , C08F8/40 , C08F30/00 , C08G85/00
Abstract: PROBLEM TO BE SOLVED: To obtain a weight-enlarged ligand for a hydrogenation catalyst in an asymmetric homogeneous system for a double bond enabling the performance of a continuous catalytic process. SOLUTION: This homogeneously soluble weight-enlarged ligand includes a homochiral active center of bis (3, 4-diarylphosphinyl)pyrrolidine.
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公开(公告)号：JP2001294540A
公开(公告)日：2001-10-23
申请号：JP2001015825
申请日：2001-01-24
Applicant: DEGUSSA , FORSCHUNGSZENTRUM JUELICH GMBH
Inventor： LAUE STEPHAN , LIESE ANDREAS , WANDREY CHRISTIAN , BURKHARDT OLAF DR , WOELTINGER JENS , BOMMARIUS ANDREAS , HENNIGES HANS , PHILIPPE JEAN-LOUIS , KARAU ANDREAS , DRAUZ KARLHEINZ
IPC: B01J31/22 , B01J31/16 , B01J31/18 , B01J31/24 , B01J31/28 , C07B31/00 , C07B53/00 , C07B61/00 , C07F9/50 , C07F15/00 , C08G77/398
Abstract: PROBLEM TO BE SOLVED: To enable the lowering of production cost by providing the use of molecular weight-enlarged, homogeneously soluble catalysts in a membrane reactor in a process for the asymmetric, continuous hydrogenation of C=C, C=N or C=0 double bonds, novel molecular weight-enlarged ligands, and asymmetric hydrogenation catalysts. SOLUTION: The ligands, catalysts, active centre, and their uses, comprises ligands such as polyacrylates, polystyrene, polysiloxanes or polyacrylates as molecular weight-enlarging agents, having an average molecular weight of 1,000 to 1,000, 000 g/mole, a metal or metal ion selected from Ru, Rh, Ir, Pd, Ni, Pt, and Co, and a representative example is N,N'-bis(2- diphenylphosphanylbenzyl) cyclohexyl-1,2-diamine as the asymmetric synthesis active center of the ligand, or the like.
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公开(公告)号：JP2001288218A
公开(公告)日：2001-10-16
申请号：JP2001013677
申请日：2001-01-22
Applicant: DEGUSSA
Inventor： KRIMMER HANS-PETER , WOELTINGER JENS , BURKHARDT OLAF DR , KLEMENT INGO DR , HENNIGES HANS , DRAUZ KARLHEINZ , BOMMARIUS ANDREAS , PHILIPPE JEAN-LOUIS , KARAU ANDREAS
IPC: C07D263/10 , B01J31/18 , B01J31/22 , B01J31/24 , C07B53/00 , C07D207/08 , C07D207/16 , C07D209/52 , C07D263/28 , C07D413/14 , C08F8/30 , C08F8/40 , C08F30/00 , C08G85/00
Abstract: PROBLEM TO BE SOLVED: To provide a ligand separable between a product and a catalyst relating to a membrane used and other ligands relating to the catalyst for the purpose of excluding problems that the catalyst is deactivated accompanying reaction progress. SOLUTION: In such case of a homogeneous soluble ligand having increased molecular weight for a hydrogenation catalyst having a homochiral active center, a specific linker may be inserted between the active center and a polymer skeleton, further the ligand is transferred into the catalyst and preferably may be used just like continuously or continuously in a membrane type reactor for an organic synthesis.
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公开(公告)号：JP2002020323A
公开(公告)日：2002-01-23
申请号：JP2001177445
申请日：2001-06-12
Applicant: DEGUSSA
Inventor： BURKHARDT OLAF , WOELTINGER JENS , KARAU ANDREAS , PHILIPPE JEAN-LOUIS , HENNIGES HANS , BOMMARIUS ANDREAS , KRIMMER HANS-PETER , DRAUZ KARLHEINZ
IPC: B01J31/06 , C07B41/06 , C07B61/00 , C07C45/29 , C07C45/30 , C07C47/02 , C07C49/04 , C08F8/06 , C08F20/10 , C08F20/36 , C08F20/60 , C08F220/14
Abstract: PROBLEM TO BE SOLVED: To provide a method for oxidizing an alcohol using a polymer containing nitrogen groups having uniform solubility. SOLUTION: An alcohol is oxidized by using an oxidizing agent and a polymer extended nitroxyl derivative having uniform solubility and obtained by the copolymerization of a mixture containing a compound of formula I.
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公开(公告)号：JP2001158752A
公开(公告)日：2001-06-12
申请号：JP2000302290
申请日：2000-10-02
Applicant: DEGUSSA
Inventor： KARAU ANDREAS , WOELTINGER JENS , BURKHARDT OLAF DR , BOMMARIUS ANDREAS , BOLDT KAI , PHILIPPE JEAN-LOUIS , HENNIGES HANS , DRAUZ KARLHEINZ
IPC: B01D69/12 , B01D61/14 , B01D67/00 , B01D71/02 , B01J19/00 , B01J19/24 , B01J31/06 , B01J31/12 , B01J31/40 , B01J35/06 , C07B53/00 , C07B61/00 , C07C29/143 , C07C35/36
Abstract: PROBLEM TO BE SOLVED: To provide a method for producing an organic compound in a film reactor by using a uniformly soluble or colloidally soluble catalyst having increased molecular weight. SOLUTION: An inorganic film having an inorganic intermediate layer which may be modified with an inorganic supporting layer and an organic group is used as a film disposed in a reactor.
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Patent Agency Ranking
公开(公告)号：WO2008122613A2
公开(公告)日：2008-10-16
申请号：PCT/EP2008054103
申请日：2008-04-04
Applicant: EVONIK DEGUSSA GMBH , KARAU ANDREAS , KOTTENHAHN MATTHIAS , DRAUZ KARLHEINZ , WINDHAB NORBERT , GRUENERT ADOLF
Inventor： KARAU ANDREAS , KOTTENHAHN MATTHIAS , DRAUZ KARLHEINZ , WINDHAB NORBERT , GRUENERT ADOLF
CPC classification number: A23L33/175 , A23L33/10 , A23V2002/00 , A23V2200/316 , A23V2250/06 , A23V2250/306
Abstract: The invention relates to a food supplement that can contain at least one amino acid, is otherwise essentially nitrogen-free, and contains at least one alpha-keto acid selected from among the group comprising alpha-ketoisocaproate, alpha-ketoisovalerate, and alpha-keto-beta-methylvalerate, and/or a salt of said alpha-keto acids. The described food supplements help build muscles while relieving metabolism in terms of nitrogen detoxification by reducing the nitrogen supply and improving nitrogen retention in the body.
Abstract translation: 本发明涉及一种膳食补充剂，其可以含有至少一个氨基酸，其中所述膳食补充剂是选自氮基本上不含否则和选自的α-酮异己酸，α-酮异戊酸和α-酮基-β-甲基戊酸中的至少一种α-酮酸，和/或 含有的α-酮酸盐。 的膳食补充剂中描述的支持肌肉的生长和减轻的同时氮解毒由减少的氮摄入体内的代谢和改善的氮保留。
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公开(公告)号：WO2008122473A2
公开(公告)日：2008-10-16
申请号：PCT/EP2008052724
申请日：2008-03-06
Applicant: EVONIK DEGUSSA GMBH , KARAU ANDREAS , KOTTENHAHN MATTHIAS , DRAUZ KARLHEINZ , WINDHAB NORBERT , GRUENERT ADOLF
Inventor： KARAU ANDREAS , KOTTENHAHN MATTHIAS , DRAUZ KARLHEINZ , WINDHAB NORBERT , GRUENERT ADOLF
CPC classification number: A23L33/175 , A23L33/10 , A23V2002/00 , A23V2200/316 , A23V2250/06 , A23V2250/306
Abstract: The invention relates to a food supplement which can contain at least one amino acid, wherein the food supplement is otherwise essentially nitrogen-free and contains at least one alpha-keto acid selected from the group alpha-ketoisocaproate, alpha-ketoisovalerate and alpha-keto-beta-methylvalerate and/or a salt of these alpha-keto acids. The food supplements described support muscle build-up and simultaneously relieve metabolism in nitrogen detoxification by reduced nitrogen supply and improve nitrogen retention in the body.
Abstract translation: 本发明涉及一种可以含有至少一种氨基酸的食品补充剂，其中该食品补充剂基本上不含氮，并且含有至少一种选自α-酮异己酸酯，α-酮异戊酸酯和α-酮基的α-酮酸 β-甲基戊酸酯和/或这些α-酮酸的盐。 所描述的食物补充剂支持肌肉积聚，同时通过减少氮气供应并改善体内的氮保留来减轻氮的解毒代谢。
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公开(公告)号：WO2010139527A3
公开(公告)日：2011-03-03
申请号：PCT/EP2010056345
申请日：2010-05-10
Applicant: EVONIK DEGUSSA GMBH , KARAU ANDREAS , MORIN NICOLAS , GERSTMEIR ROBERT
Inventor： KARAU ANDREAS , MORIN NICOLAS , GERSTMEIR ROBERT
IPC: C12P7/50
Abstract: The present invention refers to a method for the preparation of 2-keto carboxylic acid having the general formula R1-CO-COOH, wherein R1 is a branched alkyl group having 3 to 7 carbon atoms, or a salt thereof, comprising a fermentation step wherein a microorganism is grown in a culture medium in order to provide a culture broth containing 2-keto carboxylic acid or a salt thereof.
Abstract translation: 本发明涉及制备具有通式R1-CO-COOH的2-酮羧酸的方法，其中R1是具有3-7个碳原子的支链烷基或其盐，其包括发酵步骤，其中 在培养基中生长微生物以提供含有2-酮羧酸或其盐的培养液。
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9.发明申请
公开(公告)号：WO02087759B1
公开(公告)日：2003-01-16
申请号：PCT/EP0203051
申请日：2002-03-20
Applicant: DEGUSSA , WOELTINGER JENS , KRIMMER HANS-PETER , REICHERT DIETMAR , ALMENA PEREA JUAN JOSE , DRAUZ KARLHEINZ , KARAU ANDREAS
Inventor： WOELTINGER JENS , KRIMMER HANS-PETER , REICHERT DIETMAR , ALMENA PEREA JUAN JOSE , DRAUZ KARLHEINZ , KARAU ANDREAS
IPC: B01J19/18 , B01J31/06 , C07B61/00 , C07C45/72 , C07C47/19 , C07C49/17 , C07C209/60 , C07D207/16 , C08F8/30 , C08G85/00 , C07C45/74
CPC classification number: B01J31/1633 , B01J19/1893 , B01J31/06 , B01J2219/00103 , B01J2219/0011 , B01J2219/00114 , B01J2231/342 , B01J2231/346 , C07C45/72 , C07C209/60 , C07D207/16
Abstract: The invention relates to catalysts for the enantioselective aldol or Mannich reaction. Said catalysts have an increased molecular weight by being bound to a polymer and as active units that enantioselectively catalyse the aldol or Mannich reaction comprise a compound of general formula (I). The invention also relates to a method for the production and use of said catalysts.
Abstract translation: 本发明涉及催化剂的对映选择性醛醇或Mannich反应，其通过连接到聚合物和其他作为活性醛或对映选择性地曼尼希催化单元的通式（I）的化合物首先molekulargewichtsvergrössert。 一种生产和使用过程。
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公开(公告)号：CA3061210A1
公开(公告)日：2018-11-01
申请号：CA3061210
申请日：2018-04-27
Applicant: EVONIK DEGUSSA GMBH
Inventor： XUE TENG , LUPPI GIANLUIGI , SAVIETTO NATALIA RUGGERI , BOWMAN HOWARD K , SPENCER PAUL JOSEPH , KARAU ANDREAS , ZHANG JIAN-FENG , LIZIO ROSARIO , JONES MARSHALL SCOTT
IPC: C08G63/664 , A61L24/04 , C08G81/02
Abstract: The present invention is directed to bioresorbable polymers to be used as bone and tissue adhesives. The present invention is also directed to the synthesis of bioresorbable polymeric molecules bearing adhesive moieties and the use of such compounds in methods to glue and stabilize fractured bones and damaged tissues. The present invention is also directed to the use of such compounds as adhesive sealants for applications in wound care. The present invention is also directed to the use of such compounds as biodegradable ink for applications in tissue engineering and 3D printing. The present invention also relates to the use of such compounds as drug delivery platforms.
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