公开(公告)号：FI70205B

公开(公告)日：1986-02-28

申请号：FI791188

申请日：1979-04-11

Applicant: DEGUSSA

Inventor： ENGEL JUERGEN ,  KLEEMANN AXEL ,  POSSELT KLAUS ,  STORMAN FRITZ ,  THIEMER KLAUS

IPC: A61K31/135 ,  A61K20060101 ,  A61K31/13 ,  A61K31/137 ,  A61K31/43 ,  A61P9/00 ,  A61P9/08 ,  A61P9/10 ,  A61P9/12 ,  A61P29/00 ,  C07C20060101 ,  C07C67/00 ,  C07C213/00 ,  C07C213/02 ,  C07C213/08 ,  C07C215/30 ,  C07C215/60 ,  C07C221/00 ,  C07C225/06 ,  C07C225/10 ,  C07C225/14 ,  C07C97/10

Abstract: There are prepared compounds of the formula: wherein X is the group >C=O or >CH(OH), Y is the group R2 is hydrogen or C1 to C6 alkyl, R3 is hydrogen or a hydroxy group and R1 is the adamantyl group or a saturated or single unsaturated C3 to C16 cycloalkyl group where the C3 to C16 cycloalkyl group can be substituted by a C1-C4 alkyl group or a halogen atom and their salts. The compounds are useful in dilating the peripheral blood vessels and in lowering blood pressure.