6.
    发明专利
    未知

    公开(公告)号:FI883935A

    公开(公告)日:1989-03-05

    申请号:FI883935

    申请日:1988-08-25

    Applicant: DEGUSSA

    Abstract: In an improved process for the preparation of 1,6-di(N -cyano- N -guanidino)hexane from alkali metal dicyanamide and a hexamethylenediammonium salt in alcoholic solution or suspension, the reaction is carried out in the presence of a limited amount of water and a catalytic amount of a base, preferably a tertiary amine and the pH of the reaction mixture is 8 to 10 at the beginning of the reaction. After the reaction is complete, water is added to the reaction mixture in the heat, above 80 DEG C, and the coarse-crystalline product formed is separated off from the liquid phase. … Preferably, sodium dicyanamide and hexamethylenediamine dihydrochloride, preferably formed in situ from aqueous 1,6-diaminohexane and aqueous hydrochloric acid, are reacted in n-butanol in the presence of 0.1 to 20% by weight of water, relative to the solvent including water, at a pH of 9-9.5. … 1,6-di(N -cyano-N -guanidino)hexane is obtained in a high yield (85-96%) and in high purity (95-97%) and with a substantially increased space-time yield.

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