公开(公告)号：WO2012094088A1

公开(公告)日：2012-07-12

申请号：PCT/US2011/063644

申请日：2011-12-07

Applicant: EMD MILLIPORE CORPORATION ,  SCOTT, Chris ,  COLONNA, Rob ,  BARMORE, Christopher ,  TAYLOR, Todd ,  MORGAN, Daniel ,  DESILETS, Kenneth G.

Inventor： SCOTT, Chris ,  COLONNA, Rob ,  BARMORE, Christopher ,  TAYLOR, Todd ,  MORGAN, Daniel ,  DESILETS, Kenneth G.

IPC: G01N30/06

CPC classification number: G01N1/28 ,  B01D61/18 ,  B01J20/281 ,  B01L3/50255 ,  G01N1/4077 ,  G01N30/14 ,  G01N2030/146

Abstract: Sample preparation device for receiving one or more filter assemblies and one or more sample containers, each container uniquely positioned within the device to receive filtered sample from a designated filter. The device includes a body, a lid disposed on the body, a container tray, a base, an integrated seal on the body, a valve and a valve actuator. The tray can be disposed in a vacuum chamber defined by the lid and the body, and one or more sample containers can be disposed in the tray. When properly positioned in the tray in the vacuum chamber, each container is in fluid communication with a single respective filter assembly disposed in sealing relation in a respective aperture in the lid. Actuation of a valve placing the vacuum chamber under vacuum causes the lid to seal to the base and drives the simultaneous filtration of a plurality of samples.

Abstract translation: 用于接收一个或多个过滤器组件和一个或多个样品容器的样品制备装置，每个容器独特地定位在装置内以从指定的过滤器接收经过过的样品。 该装置包括主体，设置在主体上的盖，容器托盘，基座，主体上的集成密封件，阀和阀致动器。 托盘可以设置在由盖和主体限定的真空室中，并且一个或多个样品容器可以设置在托盘中。 当适当地定位在真空室中的托盘中时，每个容器与在盖中的相应孔中以密封关系设置的单个相应的过滤器组件流体连通。 将真空室置于真空下的阀的致动导致盖子密封到基座并驱动多个样品的同时过滤。

公开(公告)号：WO2015142563A1

公开(公告)日：2015-09-24

申请号：PCT/US2015/019582

申请日：2015-03-10

Applicant: EMD MILLIPORE CORPORATION

Inventor： SCOTT, Chris ,  GREENIZEN, Kurt ,  SYDLOWSKI, Paul ,  DOYLE, Jay

IPC: B01D61/18 ,  B65D50/04

CPC classification number: B65D41/0471 ,  B01L3/502 ,  B01L3/508 ,  B01L2300/042 ,  B01L2300/046 ,  B01L2300/0681 ,  B01L2300/0832 ,  B65B7/2828 ,  B65D1/0246 ,  B65D41/0414 ,  B65D41/0442 ,  B65D41/0485 ,  B65D41/06 ,  B65D2203/12 ,  B65D2251/01

Abstract: A container and a container engaging member. The container engaging member may include a sample holder or reservoir, a filtration element and collar. In the assembled condition, the sample holder or reservoir is upstream of the filtration element, the container is downstream of the filtration element, and the sample holder or reservoir is attached to the container. The container engagement member is engageable and disengageable from the bottle or container in a quick attach, quick release manner, such as with only a 90 degree, turn. A tactile and/or audible indication that the engagement is complete is provided.

Abstract translation: 容器和容器接合构件。 容器接合构件可以包括样品保持器或储存器，过滤元件和套环。 在组装状态下，样品保持器或储存器位于过滤元件的上游，容器在过滤元件的下游，并且样品保持器或储存器附接到容器。 容器接合构件以快速附接，快速释放的方式，例如只有90度的转动，可与瓶或容器接合并脱离。 提供参与完成的触觉和/或听觉指示。

公开(公告)号：WO2012154905A1

公开(公告)日：2012-11-15

申请号：PCT/US2012/037211

申请日：2012-05-10

Applicant: EMD MILLIPORE CORPORATION ,  SCOTT, Chris ,  CLARK, Phillip ,  GREENIZEN, Kurt E. ,  AMARA, Ryan A. ,  COLONNA, Robert

Inventor： SCOTT, Chris ,  CLARK, Phillip ,  GREENIZEN, Kurt E. ,  AMARA, Ryan A. ,  COLONNA, Robert

IPC: G01N31/22

CPC classification number: G01N33/558 ,  B01J20/28033 ,  B01J20/28035 ,  B01J20/2804 ,  B01L3/5023 ,  B01L9/52 ,  B01L2200/025 ,  B01L2300/0609 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/0809 ,  B01L2300/12 ,  B01L2300/126 ,  B01L2400/0487 ,  B01L2400/049 ,  G01N33/54366 ,  G01N33/56911 ,  G01N2469/10 ,  G01N2469/20

Abstract: The embodiments disclosed herein are directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.

Abstract translation: 本文公开的实施方案涉及用于在印迹膜上进行化合物检测的装置。 该装置包括多个层，包括印迹膜下面的多孔支撑层，印迹膜上方的流量分布器，以及任选的流量分配器上的孔，以将液体包含到期望的区域并允许 降低这种液体的起始体积。 优选地，流动分配器是非结合或低结合的亲水性多孔膜，例如0.22微米的膜，并且支撑层是格栅或烧结的多孔材料。 分配器和支撑件保持在一起以在膜周围形成一个信封。 在这样做时优选使用铰链，夹子和其它这样的装置。

公开(公告)号：EP2656061B1

公开(公告)日：2018-08-22

申请号：EP11855025.0

申请日：2011-12-07

Applicant: EMD Millipore Corporation

Inventor： SCOTT, Chris ,  COLONNA, Rob ,  BARMORE, Christopher ,  TAYLOR, Todd ,  MORGAN, Daniel ,  DESILETS, Kenneth G.

IPC: G01N30/14 ,  B01L3/00

CPC classification number: G01N1/28 ,  B01D61/18 ,  B01J20/281 ,  B01L3/50255 ,  G01N1/4077 ,  G01N30/14 ,  G01N2030/146

Abstract: Sample preparation device for receiving in sealing relation one or more filter assemblies and one or more sample containers, each container uniquely positioned within the device to receive filtered sample from a designated filter. The device includes a body, a lid disposed on the body, a container tray, a base, an integrated seal on the body, a valve and a valve actuator. The tray can be disposed in a vacuum chamber defined by the lid and the body, and one or more sample containers can be disposed in the tray. When properly positioned in the tray in the vacuum chamber, each container is in fluid communication with a single respective filter assembly disposed in sealing relation in a respective aperture in the lid. A single actuation of a valve causes the lid to seal to the base and drives the simultaneous filtration of a plurality of samples.

公开(公告)号：EP2707708A1

公开(公告)日：2014-03-19

申请号：EP12781832.6

申请日：2012-05-10

Applicant: EMD Millipore Corporation

Inventor： SCOTT, Chris ,  CLARK, Phillip ,  GREENIZEN, Kurt E. ,  AMARA, Ryan A. ,  COLONNA, Robert

IPC: G01N31/22

CPC classification number: G01N33/558 ,  B01J20/28033 ,  B01J20/28035 ,  B01J20/2804 ,  B01L3/5023 ,  B01L9/52 ,  B01L2200/025 ,  B01L2300/0609 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/0809 ,  B01L2300/12 ,  B01L2300/126 ,  B01L2400/0487 ,  B01L2400/049 ,  G01N33/54366 ,  G01N33/56911 ,  G01N2469/10 ,  G01N2469/20

Abstract: The embodiments disclosed herein are directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.

公开(公告)号：EP2656061A1

公开(公告)日：2013-10-30

申请号：EP11855025.0

申请日：2011-12-07

Applicant: EMD Millipore Corporation

Inventor： SCOTT, Chris ,  COLONNA, Rob ,  BARMORE, Christopher ,  TAYLOR, Todd ,  MORGAN, Daniel ,  DESILETS, Kenneth G.

IPC: G01N30/06

CPC classification number: G01N1/28 ,  B01D61/18 ,  B01J20/281 ,  B01L3/50255 ,  G01N1/4077 ,  G01N30/14 ,  G01N2030/146

Abstract: Sample preparation device for receiving in sealing relation one or more filter assemblies and one or more sample containers, each container uniquely positioned within the device to receive filtered sample from a designated filter. The device includes a body, a lid disposed on the body, a container tray, a base, an integrated seal on the body, a valve and a valve actuator. The tray can be disposed in a vacuum chamber defined by the lid and the body, and one or more sample containers can be disposed in the tray. When properly positioned in the tray in the vacuum chamber, each container is in fluid communication with a single respective filter assembly disposed in sealing relation in a respective aperture in the lid. A single actuation of a valve causes the lid to seal to the base and drives the simultaneous filtration of a plurality of samples.

公开(公告)号：EP2656061B8

公开(公告)日：2018-10-24

申请号：EP11855025.0

申请日：2011-12-07

Applicant: EMD Millipore Corporation

Inventor： SCOTT, Chris ,  COLONNA, Rob ,  BARMORE, Christopher ,  TAYLOR, Todd ,  MORGAN, Daniel ,  DESILETS, Kenneth G.

IPC: G01N30/14 ,  B01L3/00

CPC classification number: G01N1/28 ,  B01D61/18 ,  B01J20/281 ,  B01L3/50255 ,  G01N1/4077 ,  G01N30/14 ,  G01N2030/146

Abstract: Sample preparation device for receiving in sealing relation one or more filter assemblies and one or more sample containers, each container uniquely positioned within the device to receive filtered sample from a designated filter. The device includes a body, a lid disposed on the body, a container tray, a base, an integrated seal on the body, a valve and a valve actuator. The tray can be disposed in a vacuum chamber defined by the lid and the body, and one or more sample containers can be disposed in the tray. When properly positioned in the tray in the vacuum chamber, each container is in fluid communication with a single respective filter assembly disposed in sealing relation in a respective aperture in the lid. A single actuation of a valve causes the lid to seal to the base and drives the simultaneous filtration of a plurality of samples.