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公开(公告)号：WO2013022989A2
公开(公告)日：2013-02-14
申请号：PCT/US2012050021
申请日：2012-08-08
Applicant: EVOLVA SA , HOUGHTON-LARSEN JENS , HICKS PAULA M , NAESBY MICHAEL , OSTERGAARD TANGE THOMAS , HANSEN JORGEN , DALGAARD MIKKELSEN MICHAEL , HALKJAER HANSEN ESBEN , SIMON ERNESTO
Inventor： HOUGHTON-LARSEN JENS , HICKS PAULA M , NAESBY MICHAEL , OSTERGAARD TANGE THOMAS , HANSEN JORGEN , DALGAARD MIKKELSEN MICHAEL , HALKJAER HANSEN ESBEN , SIMON ERNESTO
IPC: C12N15/82
CPC classification number: C12P19/56 , C12N9/0032 , C12N9/0071 , C12N9/0073 , C12N9/1051 , C12N9/1085 , C12N9/88 , C12N9/90 , C12N15/63 , C12N15/81 , C12N15/8243 , C12P19/44 , Y02P20/52
Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol glycosides, e.g., Rebaudioside A and/or Rebaudioside D, which can be used as natural sweeteners in food products and dietary supplements.
Abstract translation: 公开了已经被工程化以表达编码UDP-糖基转移酶（UGT）的重组基因的重组微生物，植物和植物细胞。 这样的微生物，植物或植物细胞可以产生甜菊糖苷，例如雷鲍迪苷A和/或雷鲍迪苷D，其可以用作食品和膳食补充剂中的天然甜味剂。
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公开(公告)号：WO2014086842A9
公开(公告)日：2015-06-18
申请号：PCT/EP2013075510
申请日：2013-12-04
Applicant: EVOLVA SA
Inventor： LIU YAOQUAN , HANSEN JØRGEN , HOUGHTON-LARSEN JENS , MURALI MUTHUSWAMY PANCHAPAGESA , KUMAR SATHISH , RASMUSSEN NINA NICOLINE
CPC classification number: C12P33/20 , C12N9/0071 , C12N9/0073 , C12N9/1048 , C12N9/14 , C12N9/90 , C12N15/80 , C12P19/18 , C12P19/56 , C12P33/00 , C12P33/08 , C12P33/12 , C12Y114/00 , C12Y114/13132 , C12Y303/00 , C12Y504/99033
Abstract: The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.
Abstract translation: 本发明涉及借助于酶的方法来生产芒果苷。 特别地，本发明提出了可用于罗汉果苷生产的各种生物合成途径，并提供了可用于罗汉果苷生产的酶。 此外，本发明提供可用于实施本发明方法的重组宿主。
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公开(公告)号：WO2016050890A3
公开(公告)日：2016-06-30
申请号：PCT/EP2015072645
申请日：2015-09-30
Applicant: EVOLVA SA
Inventor： HOUGHTON-LARSEN JENS , KRZYSTANEK KATARZYNA , SEMMLER ANGELIKA , HANSEN IVER KLAVS RIISHEDE , DAMKIAER SOREN , LIU GARY , LIU YAOQUAN , HANSEN JORGEN , KUMAR SATHISH , MURALI MUTHUSWAMY PANCHAPAGESA , RASMUSSEN NINA NICOLINE
IPC: C12N1/19 , C12N9/02 , C12N9/06 , C12N9/10 , C12N9/14 , C12N9/90 , C12P19/18 , C12P19/56 , C12P33/00
CPC classification number: C12P33/00 , A23L27/36 , A23V2002/00 , C07H1/06 , C12N9/0014 , C12N9/0042 , C12N9/0071 , C12N9/0073 , C12N9/1051 , C12N9/14 , C12N9/90 , C12N15/00 , C12P19/18 , C12P19/56
Abstract: Methods for recombinant and enzymatic production of mogroside compounds and compositions containing mogroside compounds are provided by this invention.
Abstract translation: 用于重组和酶促生产罗汉果苷化合物和含有罗汉果苷化合物的组合物的方法由本发明提供。
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公开(公告)号：WO2016038095A3
公开(公告)日：2016-05-12
申请号：PCT/EP2015070620
申请日：2015-09-09
Applicant: EVOLVA SA , ROBERTSEN HELENE LUNDE , ANDERSEN IBEN NORDMARK , TAKOS ADAM MATTHEW , HALLWYL SWEE CHUANG LIM , AMBRI FRANCESCA , ASENSIO MANUEL QUIROS
Inventor： ROBERTSEN HELENE LUNDE , ANDERSEN IBEN NORDMARK , TAKOS ADAM MATTHEW , HALLWYL SWEE CHUANG LIM , AMBRI FRANCESCA , ASENSIO MANUEL QUIROS , MIKKELSEN MICHAEL DALGAARD , HOUGHTON-LARSEN JENS , DOUCHIN VERONIQUE , DYEKJAER JANE DANNOW , CARLSEN SIMON , RASMUSSEN NINA NICOLINE , HANSEN ESBEN HALKJAER
IPC: A23L27/30 , C12N1/18 , C12N9/02 , C12N9/10 , C12N9/88 , C12N9/90 , C12N15/52 , C12P5/00 , C12P19/44 , C12P19/56
CPC classification number: C12P19/56 , A23L27/36 , A23V2002/00 , C07H15/256 , C07K2319/00 , C12N9/0042 , C12N9/0073 , C12N9/1085 , C12N9/88 , C12N9/90 , C12N15/52 , C12Y106/02004 , C12Y114/13078 , C12Y114/13079 , C12Y205/01029 , C12Y402/03019 , C12Y505/01013
Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
Abstract translation: 本发明涉及重组微生物和用于生产甜菊糖苷和甜菊糖苷前体的方法。
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公开(公告)号：BR122021015508B1
公开(公告)日：2022-03-29
申请号：BR122021015508
申请日：2012-08-08
Applicant: EVOLVA SA
Inventor： SIMON ERNESTO , HANSEN ESBEN HALKJAER , HOUGHTON-LARSEN JENS , HANSEN JORGEN , MICHAEL DALGAARD MIKKELSEN , NAESBY MICHAEL , PAULA M HICKS , SABINA DE ANDRADE PEREIRA TAVARES , TANGE THOMAS OSTERGAARD
Abstract: trata-se de microrganismos recombinantes, plantas, e células vegetais que foram modificados por engenharia genética para expressar genes recombinantes que codificam udp-glicosil transferases (ugts). esses microrganismos, plantas, ou células vegetais podem produzir glicosídeos de esteviol, por exemplo, rebaudiosídeo a e/ou rebaudiosídeo d, que podem ser usados como adoçantes naturais em produtos alimentícios e em suplementos alimentares.
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Patent Agency Ranking
公开(公告)号：CA2843606C
公开(公告)日：2021-10-05
申请号：CA2843606
申请日：2012-08-08
Applicant: EVOLVA SA
Inventor： HOUGHTON-LARSEN JENS , HICKS PAULA M , NAESBY MICHAEL , OSTERGAARD TANGE THOMAS , HANSEN JORGEN , DALGAARD MIKKELSEN MICHAEL , HALKJAER HANSEN ESBEN , ERNESTO SIMON , DE ANDRADE PEREIRA TAVARES SABINA
IPC: C12P19/56 , C07H15/256 , C07K14/415 , C12N1/19 , C12N9/00 , C12N9/10 , C12N9/16 , C12N9/24 , C12N15/29 , C12N15/52 , C12N15/54 , C12N15/63 , C12N15/81
Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol glycosides, e.g., Rebaudioside A and/or Rebaudioside D, which can be used as natural sweeteners in food products and dietary supplements.
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公开(公告)号：AU2020200887A1
公开(公告)日：2020-02-27
申请号：AU2020200887
申请日：2020-02-07
Applicant: EVOLVA SA
Inventor： ROBERTSEN HELENE LUNDE , ANDERSEN IBEN NORDMARK , TAKOS ADAM MATTHEW , HALLWYL SWEE CHUANG LIM , AMBRI FRANCESCA , ASENSIO MANUEL QUIROS , MIKKELSEN MICHAEL DALGAARD , HOUGHTON-LARSEN JENS , DOUCHIN VERONIQUE , DYEKJAER JANE DANNOW , CARLSEN SIMON , RASMUSSEN NINA NICOLINE , HANSEN ESBEN HALKJAER
IPC: A23L27/30 , C12N1/18 , C12N9/02 , C12N9/10 , C12N9/88 , C12N9/90 , C12N15/52 , C12P5/00 , C12P19/44 , C12P19/56
Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
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公开(公告)号：AU2019250137A1
公开(公告)日：2019-10-31
申请号：AU2019250137
申请日：2019-10-16
Applicant: EVOLVA SA
Inventor： LIU YAOQUAN , HANSEN JORGEN , HOUGHTON-LARSEN JENS , MURALI P M , KUMAR SATHISH
Abstract: Methods and materials for biosynthesis of mogroside compounds are described.
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公开(公告)号：SG10201901957SA
公开(公告)日：2019-04-29
申请号：SG10201901957S
申请日：2015-09-09
Applicant: EVOLVA SA
Inventor： MIKKELSEN MICHAEL DALGAARD , HOUGHTON-LARSEN JENS , ROBERTSEN HELENE LUNDE , ANDERSEN IBEN NORDMARK , DOUCHIN VERONIQUE , DYEKJAER JANE DANNOW , TAKOS ADAM MATTHEW , HALLWYL SWEE CHUANG LIM , CARLSEN SIMON , RASMUSSEN NINA NICOLINE , AMBRI FRANCESCA , ASENSIO MANUEL QUIROS , HANSEN ESBEN HALKJAER
Abstract: PRODUCTION OF STEVIOL GLYCOSIDES IN RECOMBINANT HOSTS The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors. [Figure 1]
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公开(公告)号：AU2012294452C1
公开(公告)日：2017-11-30
申请号：AU2012294452
申请日：2012-08-08
Applicant: EVOLVA SA
Inventor： HOUGHTON-LARSEN JENS , HICKS PAULA M , NAESBY MICHAEL , OSTERGAARD TANGE THOMAS , HANSEN JORGEN , DALGAARD MIKKELSEN MICHAEL , HALKJAER HANSEN ESBEN , SIMON ERNESTO
Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce steviol glycosides, e.g., Rebaudioside A and/or Rebaudioside D, which can be used as natural sweeteners in food products and dietary supplements.
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