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Patent Agency Ranking
公开(公告)号：WO2021101893A1
公开(公告)日：2021-05-27
申请号：PCT/US2020/060892
申请日：2020-11-17
Applicant: FLUIDIGM CORPORATION
Inventor： SANDKUIJL, Daaf , CARPINO, Alan
Abstract: A microscopy apparatus comprises a microscope comprising a stage configured to hold a tissue sample, a UV laser assembly configured to emit a UV laser beam to a viewing area of the tissue sample, and an IR laser assembly configured to emit an IR laser beam to the viewing area of the tissue sample. The UV and IR laser assemblies are oriented so as to emit the respective UV and IR laser beams in a same direction.
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公开(公告)号：WO2020150236A1
公开(公告)日：2020-07-23
申请号：PCT/US2020/013509
申请日：2020-01-14
Applicant: FLUIDIGM CANADA INC. , FLUIDIGM CORPORATION
Inventor： LOBODA, Alexander , SANDKUIJL, Daaf , CAREW, Adam
IPC: C12Q1/6872 , G01N27/62 , G01N33/48 , H01J49/00
Abstract: As described herein, one or more parameters of a direct ionization imaging mass spectrometer (IMS) may be set to obtain a desired plasma and deliver it to a mass detector. Depending on the application, certain parameters may be predetermined (e.g., a spot size given a desired resolution) and, as described herein, other parameters can be adjusted to obtain the desired plasma properties. Also included is sample preparation suitable for direct ionization IMS and/or other imaging modalities.
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公开(公告)号：WO2020055813A1
公开(公告)日：2020-03-19
申请号：PCT/US2019/050333
申请日：2019-09-10
Applicant: FLUIDIGM CANADA INC. , FLUIDIGM CORPORATION
Inventor： SANDKUIJL, Daaf , LOBODA, Alexander , CAREW, Adam , LAKSHMAN, Minalini
Abstract: This disclosure relates to systems and methods for high speed modulation sample imaging. Disclosed herein are systems and methods for performing imaging mass cytometry, including analysis of labelling atoms by elemental (e.g., atomic) mass spectrometry. Aspects include a sampling system having, and method of using, a femtosecond (fs) laser and/or laser scanning. Alternatively or in addition, aspects include systems and methods for co-registering other imaging modalities with imaging mass cytometry.
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公开(公告)号：WO2020055810A1
公开(公告)日：2020-03-19
申请号：PCT/US2019/050330
申请日：2019-09-10
Applicant: FLUIDIGM CANADA INC. , FLUIDIGM CORPORATION
Inventor： SANDKUIJL, Daaf , LOBODA, Alexander , CAREW, Adam , ASKARPOUR, Khashayar
Abstract: The invention relates to systems and methods for autofocusing in imaging mass spectrometry. The present invention provides improvements over current IMS and IMG apparatus and methods through an autofocus component including plurality of apertures in the autofocus system, such as a plurality of apertures arranged in 2 dimensions. As a plurality of apertures is used the autofocus system provides redundancy in the event that measurement of focus on the sample from the illuminating radiation passed through one or more of the apertures fails so reducing the number of unsuccessful autofocus attempts.
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公开(公告)号：EP4062221A1
公开(公告)日：2022-09-28
申请号：EP20889422.0
申请日：2020-11-17
Applicant: Fluidigm Corporation
Inventor： SANDKUIJL, Daaf , CARPINO, Alan
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