公开(公告)号：DK3235561T3

公开(公告)日：2019-01-28

申请号：DK15870074

申请日：2015-12-18

Applicant: FUJIFILM CORP

Inventor： SUGIYAMA SUSUMU ,  YAMADA NAOKI ,  SUGIYAMA SHIGEHISA ,  OKUBO YOHEI

IPC: B01J13/04 ,  A61K9/127 ,  B01F3/08 ,  B82Y5/00 ,  B82Y40/00

公开(公告)号：PL3235561T3

公开(公告)日：2019-06-28

申请号：PL15870074

申请日：2015-12-18

Applicant: FUJIFILM CORP

Inventor： SUGIYAMA SUSUMU ,  YAMADA NAOKI ,  SUGIYAMA SHIGEHISA ,  OKUBO YOHEI

IPC: B01J13/04 ,  A61K9/127 ,  B01F3/08 ,  B82Y5/00 ,  B82Y40/00

公开(公告)号：EP3235562A4

公开(公告)日：2017-12-13

申请号：EP15870075

申请日：2015-12-18

Applicant: FUJIFILM CORP

Inventor： SUGIYAMA SUSUMU ,  YAMADA NAOKI ,  SUGIYAMA SHIGEHISA ,  OKUBO YOHEI ,  SASAKI TAKASHI ,  ISHIGURO TETSU

IPC: B01J13/04 ,  A61K9/127 ,  B01D1/00 ,  B01D5/00 ,  B01F3/08 ,  B01F5/10 ,  B01F7/00 ,  B01F7/16 ,  B01F7/32 ,  B01F15/02 ,  B01F15/06

CPC classification number: B01J13/04 ,  A61K9/127 ,  A61K9/1271 ,  A61K9/1277 ,  B01D1/00 ,  B01D5/006 ,  B01F3/0807 ,  B01F5/10 ,  B01F7/0075 ,  B01F2003/0842 ,  B01F2215/0032

Abstract: Disclosed herein are a method for producing a liposome which is capable of reducing the facility costs and also capable of rapid desolvation, and an apparatus for producing a liposome which is for use in the above-mentioned method. Provided is a method for producing a liposome, including a stirring step of stirring a mixed liquid containing an oil phase in which at least one lipid is dissolved in an organic solvent and a water phase, and an evaporating step of evaporating an organic solvent from the mixed liquid, in which the condensed organic solvent is removed by passing a gas having a temperature not higher than the dew point of the solvent in the evaporating step.

公开(公告)号：EP3235561A4

公开(公告)日：2017-12-13

申请号：EP15870074

申请日：2015-12-18

Applicant: FUJIFILM CORP

Inventor： SUGIYAMA SUSUMU ,  YAMADA NAOKI ,  SUGIYAMA SHIGEHISA ,  OKUBO YOHEI

IPC: B01J13/04 ,  A61K9/127 ,  B01F3/08 ,  B82Y5/00 ,  B82Y40/00

CPC classification number: A61K9/1277 ,  A61K9/127 ,  A61K9/1271 ,  A61K31/7068 ,  B01F3/08 ,  B01F3/0807 ,  B01F5/0206 ,  B01F5/10 ,  B01F2215/0032 ,  B01J13/04 ,  B01J13/08 ,  B82Y5/00 ,  B82Y40/00

Abstract: Disclosed herein are a method for producing a miniaturized liposome on a large production scale, and an apparatus for producing a liposome which is to be used in the above-mentioned method. Provided is a method for producing a liposome, including a step of stirring a mixture containing an oil phase in which at least one lipid is dissolved in an organic solvent and a water phase in a first tank of an apparatus having the first tank and a circulation path, in which the ratio of the capacity of the circulation path to the total capacity of the tank and the circulation path is 0.4 or less and/or the time required for the mixture to return to the first tank after being discharged therefrom is within 2.0 minutes.