公开(公告)号：EP1283214A4

公开(公告)日：2004-09-22

申请号：EP01922014

申请日：2001-04-23

Applicant: FUSO PHARMACEUTICAL IND

Inventor： WAKAMIYA NOBUTAKA ,  KESHI HIROYUKI ,  OHTANI KATSUKI ,  SAKAMOTO TAKASHI ,  KISHI YUICHIRO

IPC: C07K14/47 ,  C07K14/785 ,  C12N15/12 ,  A01K67/027 ,  C07K16/18 ,  C12P21/02 ,  G01N33/53

CPC classification number: C07K14/4726 ,  A01K2217/05 ,  C07K14/785

Abstract: Isolated collectin (CL-L2s) genes containing a base sequence represented by SEQ ID NO:1, 3, 5, 7, 9, 12, 36, 38 or 40 relating to novel collectins which are expected as exhibiting an antibacterial activity, an antiviral activity, etc. particularly in the human body; and isolated collectin proteins containing an amino acid sequence represented by SEQ ID NO:2, 4, 6, 8, 10, 13, 37, 39 or 41 and derivatives and fragments thereof.

公开(公告)号：EP1518557A4

公开(公告)日：2008-12-03

申请号：EP03738567

申请日：2003-06-30

Applicant: FUSO PHARMACEUTICAL IND

Inventor： WAKAMIYA NOBUTAKA ,  OHTANI KATSUKI ,  SAKAMOTO TAKASHI ,  KESHI HIROYUKI ,  KISHI YUICHIRO

IPC: A61K38/17 ,  A61P31/18 ,  A61P37/04 ,  A61P43/00 ,  A61K38/16

CPC classification number: A61K38/1709

Abstract: It is intended to disclose an anti-HIV agent which contains as the active ingredient a mannose-binding protein (MBP) and efficaciously contributes to the treatment of patients infected with human immunodeficiency virus (HIV) and inhibits the progress of the disease. It is also intended to disclose a method of evaluating an anti-HIV activity exerted by the MBP which involves the step of culturing HIV-infected cells in the presence of the MBP.

公开(公告)号：DE60126602T2

公开(公告)日：2007-11-22

申请号：DE60126602

申请日：2001-04-23

Applicant: FUSO PHARMACEUTICAL IND

Inventor： WAKAMIYA NOBUTAKA ,  KESHI HIROYUKI ,  OHTANI KATSUKI ,  SAKAMOTO TAKASHI ,  KISHI YUICHIRO

IPC: C07K14/47 ,  A01K67/027 ,  C07K14/785 ,  C07K16/18 ,  C12N15/12 ,  C12P21/02 ,  G01N33/53

公开(公告)号：ES2281413T3

公开(公告)日：2007-10-01

申请号：ES01922014

申请日：2001-04-23

Applicant: FUSO PHARMACEUTICAL IND

Inventor： WAKAMIYA NOBUTAKA ,  KESHI HIROYUKI ,  OHTANI KATSUKI ,  SAKAMOTO TAKASHI ,  KISHI YUICHIRO

IPC: C07K14/47 ,  A01K67/027 ,  C07K14/785 ,  C07K16/18 ,  C12N15/12 ,  C12P21/02 ,  G01N33/53

Abstract: Una proteína que comprende una secuencia amino-acídica que consiste en 245 aminoácidos expuestos en la posición aminoacídica 1-245 de la SEQ ID NO: 4.

公开(公告)号：AU2003246119A1

公开(公告)日：2004-01-19

申请号：AU2003246119

申请日：2003-06-30

Applicant: FUSO PHARMACEUTICAL IND

Inventor： WAKAMIYA NOBUTAKA ,  OHTANI KATSUKI ,  SAKAMOTO TAKASHI ,  KESHI HIROYUKI ,  KISHI YUICHIRO

IPC: A61K38/17 ,  A61P31/18 ,  A61P37/04 ,  A61P43/00 ,  A61K38/16

Abstract: Disclosed are anti-HIV agents which comprise a mannose binding protein (MBP) as an active component and are useful for effectively inhibiting progress of diseases state in and useful in therapy for individuals infected with human immunodeficiency virus (HIV). Also disclosed are a method for evaluating an anti-HIV activity of MBP comprising the step of culturing HIV infected cells under the presence of MBP.

公开(公告)号：CA2406884A1

公开(公告)日：2002-10-18

申请号：CA2406884

申请日：2001-04-23

Applicant: FUSO PHARMACEUTICAL IND

Inventor： KESHI HIROYUKI ,  WAKAMIYA NOBUTAKA ,  SAKAMOTO TAKASHI ,  KISHI YUICHIRO ,  OHTANI KATSUKI

IPC: C07K14/47 ,  C07K14/785 ,  C12N15/12 ,  A01K67/027 ,  C07K16/18 ,  C12P21/02 ,  G01N33/53

Abstract: Isolated collectin (CL-L2s) genes containing a base sequence represented by SEQ ID NO:1, 3, 5, 7, 9, 12, 36, 38 or 40 relating to novel collectins which are expected as exhibiting an antibacterial activity, an antiviral activity, etc. particularly in the human body; and isolated collectin proteins containing an amino acid sequence represented by SEQ ID NO:2, 4, 6, 8, 10, 1 3, 37, 39 or 41 and derivatives and fragments thereof.

公开(公告)号：DK1283214T3

公开(公告)日：2007-06-11

申请号：DK01922014

申请日：2001-04-23

Applicant: FUSO PHARMACEUTICAL IND

Inventor： WAKAMIYA NOBUTAKA ,  KESHI HIROYUKI ,  OHTANI KATSUKI ,  SAKAMOTO TAKASHI ,  KISHI YUICHIRO

IPC: C07K14/47 ,  A01K67/027 ,  C07K14/785 ,  C07K16/18 ,  C12N15/12 ,  C12P21/02 ,  G01N33/53

公开(公告)号：DE60126602D1

公开(公告)日：2007-03-29

申请号：DE60126602

申请日：2001-04-23

Applicant: FUSO PHARMACEUTICAL IND

Inventor： WAKAMIYA NOBUTAKA ,  KESHI HIROYUKI ,  OHTANI KATSUKI ,  SAKAMOTO TAKASHI ,  KISHI YUICHIRO

IPC: C07K14/47 ,  A01K67/027 ,  C07K14/785 ,  C07K16/18 ,  C12N15/12 ,  C12P21/02 ,  G01N33/53

公开(公告)号：CA2472438A1

公开(公告)日：2004-01-08

申请号：CA2472438

申请日：2003-06-30

Applicant: FUSO PHARMACEUTICAL IND

Inventor： SAKAMOTO TAKASHI ,  KESHI HIROYUKI ,  OHTANI KATSUKI ,  KISHI YUICHIRO ,  WAKAMIYA NOBUTAKA

IPC: A61K38/17 ,  A61P31/18 ,  A61P37/04 ,  A61P43/00 ,  A61K38/16

Abstract: It is intended to disclose an anti-HIV agent which contains as the active ingredient a mannose-binding protein (MBP) and efficaciously contributes to the treatment of patients infected with human immunodeficiency virus (HIV) a nd inhibits the progress of the disease. It is also intended to disclose a meth od of evaluating an anti-HIV activity exerted by the MBP which involves the ste p of culturing HIV-infected cells in the presence of the MBP.

公开(公告)号：PT1283214E

公开(公告)日：2007-03-30

申请号：PT01922014

申请日：2001-04-23

Applicant: FUSO PHARMACEUTICAL IND

Inventor： WAKAMIYA NOBUTAKA ,  KESHI HIROYUKI ,  OHTANI KATSUKI ,  SAKAMOTO TAKASHI ,  KISHI YUICHIRO

IPC: C07K14/47 ,  C07K14/785 ,  C07K16/18 ,  C12N15/12 ,  C12P21/02 ,  G01N33/53