公开(公告)号：YU29076A

公开(公告)日：1982-08-31

申请号：YU29076

申请日：1976-02-06

Applicant: GLAXO LAB LTD

Inventor： FLEMING I D ,  NOBEL D ,  NOBLE H ,  WALL W

IPC: C07D503/00 ,  C12P17/18 ,  C07D498/00 ,  A61K31/33

Abstract: The invention provides the compound (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0]hept ane-2-carboxylic acid and its salts in purified form and pharmaceutical compositions containing them and a process for the purification of such compounds by conversion in aqueous media to the lithium salt of the above acid and precipitation thereof.