公开(公告)号：ES2116645T3

公开(公告)日：1998-07-16

申请号：ES95106329

申请日：1995-04-27

Applicant: HOECHST AG

Inventor： BELLER MATTHIAS DR ,  FISCHER HARTMUT DR ,  GERDAU THOMAS DR ,  GROSS PETER

IPC: C07C231/08 ,  C07C231/12 ,  C07C233/47 ,  C07C233/49 ,  C07C233/52 ,  C07C233/53 ,  C07C233/63 ,  C07C233/82 ,  C07C233/83

Abstract: Prodn. of N-acyl glycine derivs. of formula (I) comprises (a) reacting a carboxamide of formula (II) with an aldehyde of formula (III) in the presence of a solvent and an acid to form an acylaminomethanol deriv. of formula (IV), and (b) carbonylating (IV) in the presence of a Co carbonyl catalyst at 20-150 deg. C and a CO pressure of 1-150 bar. R1 = H, linear, branched or cyclic 1-26C alkyl, mono- or polyunsaturated linear, branched or cyclic 2-24C alkenyl, 6-18C aryl, (1-10C)alkyl(6-18C) aryl or opt. polyunsaturated (1-10C)alkenyl(6-18C)aryl; R2 = H, linear, branched or cyclic 1-26C alkyl, mono- or polyunsaturated linear, branched or cyclic 2-23C alkenyl, 6-18C aryl, (1-10C)alkyl(6-18C)aryl or opt. polyunsaturated (2-10C)alkenyl(6-18C)aryl; R3 = H, linear branched or cyclic 1-10C alkyl, mono- or polyunsaturated linear, branched or cyclic 2-10C alkenyl, 6-18C aryl, (1-10C)alkyl(6-18C)aryl or opt. polyunsaturated (2-10C)alkenyl(6-18C)aryl.

公开(公告)号：DE19523890C1

公开(公告)日：1996-11-28

申请号：DE19523890

申请日：1995-06-30

Applicant: HOECHST AG

Inventor： BELLER MATTHIAS DR ,  TAFESH ACHMED DR ,  FISCHER RICHARD WALTER DR ,  SCHARBERT BERND DR

IPC: B01J31/18 ,  B01J31/22 ,  C07B61/00 ,  C07D301/12 ,  C07D301/14 ,  C07D303/02 ,  C07D303/04 ,  C07D303/24 ,  C07D303/32 ,  C07D493/04 ,  C07B53/00 ,  C07D301/06 ,  C07D301/19 ,  C07F13/00

公开(公告)号：DE4415681A1

公开(公告)日：1995-11-16

申请号：DE4415681

申请日：1994-05-04

Applicant: HOECHST AG

Inventor： KOHLPAINTNER CHRISTIAN W DR ,  BELLER MATTHIAS DR

IPC: B01J31/16 ,  B01J31/18 ,  B01J31/24 ,  C07B41/08 ,  C07B61/00 ,  C07C51/10 ,  C07C57/32 ,  C07C67/36 ,  C07C69/612 ,  C07C69/614 ,  C07C69/616 ,  C07C69/65 ,  C07C69/73 ,  C07C69/738 ,  C07C205/56 ,  C07C229/40 ,  C07C255/57 ,  C07C309/57 ,  C07C309/72 ,  C07C311/15 ,  C11B9/00 ,  C07C53/23 ,  C07C22/04 ,  C07C53/132 ,  C07C53/15 ,  C07F15/00 ,  C07F15/02 ,  C07F15/04 ,  C07F15/06

Abstract: Prepn. of aryl ethanoic acid derivs. of formula (I) comprises carbonylating an aryl methyl halide of formula (II) in a two phase system using a water-soluble metal complex as catalyst: R = H, halo, CO (1-8C) alkyl, OCO (1-8C) alkyl, 1-8C alkyl, Ph (opt. substd. by OH or NH2); R = H, 1-8C alkyl or Ph; Ar = phenyl, naphthyl, anthracenyl or phenanthrenyl (each opt. substd. by halo, OH, polyfluoro (1-8C) alkyl, CN, (1-4C) alkoxy, NO2, COO (1-4C) alkyl, CON (1-4C alkyl)2, NH (1-4C) alkyl, N (1-4C alkyl)2, NL2, SO3H, SO3 (1-4C) alkyl, SO2NH2, OCO (1-4C) alkyl, CH2-halo).

公开(公告)号：DE59403144D1

公开(公告)日：1997-07-24

申请号：DE59403144

申请日：1994-01-03

Applicant: HOECHST AG

Inventor： BELLER MATTHIAS DR ,  FISCHER HARTMUT ,  STRUTZ HEINZ DR

IPC: B01J23/44 ,  C07B37/04 ,  C07B61/00 ,  C07C37/11 ,  C07C39/19 ,  C07C47/542 ,  C07C47/55 ,  C07C67/343 ,  C07C67/347 ,  C07C69/618 ,  C07C69/76 ,  C07C69/86 ,  C07C69/92 ,  C07C201/12 ,  C07C205/06 ,  C07C233/05 ,  C07C233/11 ,  C07C233/20 ,  C07C235/34 ,  C07C237/06 ,  C07C253/30 ,  C07C255/32 ,  C07C255/50 ,  C07C255/51 ,  C07C255/54 ,  C07C255/55 ,  C07C255/57 ,  C07C255/58

Abstract: Aromatic olefins of the formula (I) in which R -R denote hydrogen, alkyl(C1-C8), alkoxy(C1-C5), phenyl, fluorine, chlorine, bromine, -OH, -NO2, -CN, -CHO, -CO(alkyl)(C1-C4), -CO phenyl, - COO alkyl(C1-C4), -OCO alkyl(C1-C4), -NHCO alkyl(C1-C4), -CF3, - NH2, -NH alkyl(C1-C4) or -N(alkyl(C1-C4))2 and R denotes hydrogen, alkyl(C1-C8), phenyl, fluorine, chlorine, bromine, -OH, -NO2, - CN, -CHO or -OCO alkyl(C1-C4), X denotes, inter alia, alkenyl (C2-C12) or cycloalkenyl(C4-C8) or the group in which R and R independently of one another are hydrogen or methyl, and Y denotes -phenyl, -CN, -COOH, -COO alkyl(C1-C12), - COO phenyl, - CON(alkyl(C1-C12))2, -CONH2, -CON(phenyl)2, -CO alkyl(C1-C12), -CO phenyl, -O alkyl(C1-C12) or - O phenyl or represents the radical in which R -R have the abovementioned meanings, are prepared by reacting an aryldiazonium salt of the formula (2) in which R -R have the meanings mentioned and Z represents the equivalent of an anion of an acid of pKa less than 7, with an olefin of the formula (3> HX (3> in which X has the meaning mentioned, in the presence of catalytic amounts of a heterogeneous palladium catalyst in an organic solvent at temperatures from -20@C to 150@C.

公开(公告)号：DE4439836C1

公开(公告)日：1996-06-05

申请号：DE4439836

申请日：1994-11-08

Applicant: HOECHST AG

Inventor： BELLER MATTHIAS DR ,  PFIRMANN RALF DR

IPC: C07B53/00 ,  C07C253/30 ,  C07C253/34 ,  C07C255/37

Abstract: Prodn. of cis-4-(2,2,3,3-tetrafluoropropoxy)cinnamic acid nitrile (1a) and trans-4-(2,2,3,3-tetrafluoropropoxy)cinnamic acid nitrile (1b), or prodn. of one of (1a) and (1b), comprises a) fractional distillation of a mixt. contg. (1a) + (1b) under reduced pressure to yield a fraction contg. at least 80 wt.% (1a) and a fraction contg. at least 80 wt.% (1b); and (b) purifying the fractions further by fractional crystallisation or melt crystallisation; or (c) isomerising one fraction to the thermodynamic equilibrium mixt. of (1a) + (1b) and returning to step a). Cis-4-(2,2,3,3-tetrafluoropropoxy)cinnamic acid nitrile of formula (Ia) and the trans isomer of formula (1b) are new.

公开(公告)号：DE59301869D1

公开(公告)日：1996-04-18

申请号：DE59301869

申请日：1993-09-02

Applicant: HOECHST AG

Inventor： BELLER MATTHIAS DR ,  FISCHER HARTMUT ,  STRUTZ HEINZ DR

IPC: C07B61/00 ,  B01J31/18 ,  C07B37/04 ,  C07C2/86 ,  C07C15/46 ,  C07C15/52 ,  C07C17/266 ,  C07C25/24 ,  C07C37/18 ,  C07C39/21 ,  C07C41/24 ,  C07C43/20 ,  C07C45/68 ,  C07C59/48 ,  C07C67/347 ,  C07C205/06 ,  C07C205/56 ,  C07C253/30 ,  C07C255/50

公开(公告)号：DE4415682A1

公开(公告)日：1995-11-09

申请号：DE4415682

申请日：1994-05-04

Applicant: HOECHST AG

Inventor： KOHLPAINTNER CHRISTIAN W DR ,  BELLER MATTHIAS DR

IPC: B01J31/22 ,  B01J31/24 ,  B01J31/40 ,  C07B41/06 ,  C07B61/00 ,  C07C51/10 ,  C07C51/14 ,  C07F15/00 ,  C07C309/36 ,  C07F9/50

Abstract: Novel Pd cpds. contg. sulphonated 2,2'-bis-(diphenyl- phosphinomethyl)-1,1'-bi-naphthalene cpds. of formula (I) as ligands are claimed, as is also the prepn. of these novel cpds. by reacting Pd (in)organic salts or complexes with (I) (where, Ar = C6H4SO3M; M = H, ammonium, monovalent metal or equiv. of a multi-valent metal; Ph = phenyl; and n, m, x, y, u, and v = 0, 1 or 2, pref. 0 or 1).

公开(公告)号：DE4316923A1

公开(公告)日：1994-11-24

申请号：DE4316923

申请日：1993-05-20

Applicant: HOECHST AG

Inventor： BELLER MATTHIAS DR ,  GERDAU THOMAS DR ,  STRUTZ HEINZ DR

IPC: B01J21/18 ,  B01J23/44 ,  B01J31/02 ,  C07C209/32 ,  C07C245/20 ,  C07D295/135 ,  C07C211/52 ,  C07C209/36 ,  C07C211/43 ,  C07C217/78 ,  C07D295/28 ,  C09B29/01

Abstract: A process for the preparation of aromatic amines by reducing the corresponding nitro compound with phosphorous acid in the presence of a heterogeneous palladium catalyst is characterised in that a phosphorous acid is employed which can be obtained as a by-product in the preparation of organic acid chlorides from organic acids and phosphorus trichloride. The process according to the invention allows aromatic amines to be prepared economically, in high yield, under mild conditions and in a chemoselective fashion. The process is also advantageous from the ecological point of view since it employs a waste material whose incineration or decontamination would involve high energy consumption.

公开(公告)号：AU697803B2

公开(公告)日：1998-10-15

申请号：AU1771995

申请日：1995-04-27

Applicant: HOECHST AG

Inventor： BELLER MATTHIAS DR ,  GROSS PETER ,  GERDAU THOMAS DR ,  FISCHER HARTMUT DR

IPC: C07C231/08 ,  C07C231/12 ,  C07C233/47 ,  C07C233/49 ,  C07C233/52 ,  C07C233/53 ,  C07C233/63 ,  C07C233/82 ,  C07C233/83

Abstract: Prodn. of N-acyl glycine derivs. of formula (I) comprises (a) reacting a carboxamide of formula (II) with an aldehyde of formula (III) in the presence of a solvent and an acid to form an acylaminomethanol deriv. of formula (IV), and (b) carbonylating (IV) in the presence of a Co carbonyl catalyst at 20-150 deg. C and a CO pressure of 1-150 bar. R1 = H, linear, branched or cyclic 1-26C alkyl, mono- or polyunsaturated linear, branched or cyclic 2-24C alkenyl, 6-18C aryl, (1-10C)alkyl(6-18C) aryl or opt. polyunsaturated (1-10C)alkenyl(6-18C)aryl; R2 = H, linear, branched or cyclic 1-26C alkyl, mono- or polyunsaturated linear, branched or cyclic 2-23C alkenyl, 6-18C aryl, (1-10C)alkyl(6-18C)aryl or opt. polyunsaturated (2-10C)alkenyl(6-18C)aryl; R3 = H, linear branched or cyclic 1-10C alkyl, mono- or polyunsaturated linear, branched or cyclic 2-10C alkenyl, 6-18C aryl, (1-10C)alkyl(6-18C)aryl or opt. polyunsaturated (2-10C)alkenyl(6-18C)aryl.

公开(公告)号：DE59501814D1

公开(公告)日：1998-05-14

申请号：DE59501814

申请日：1995-04-27

Applicant: HOECHST AG

Inventor： BELLER MATTHIAS DR ,  FISCHER HARTMUT DR ,  GERDAU THOMAS DR ,  GROSS PETER

IPC: C07C231/08 ,  C07C231/12 ,  C07C233/47 ,  C07C233/49 ,  C07C233/52 ,  C07C233/53 ,  C07C233/63 ,  C07C233/82 ,  C07C233/83

Abstract: Prodn. of N-acyl glycine derivs. of formula (I) comprises (a) reacting a carboxamide of formula (II) with an aldehyde of formula (III) in the presence of a solvent and an acid to form an acylaminomethanol deriv. of formula (IV), and (b) carbonylating (IV) in the presence of a Co carbonyl catalyst at 20-150 deg. C and a CO pressure of 1-150 bar. R1 = H, linear, branched or cyclic 1-26C alkyl, mono- or polyunsaturated linear, branched or cyclic 2-24C alkenyl, 6-18C aryl, (1-10C)alkyl(6-18C) aryl or opt. polyunsaturated (1-10C)alkenyl(6-18C)aryl; R2 = H, linear, branched or cyclic 1-26C alkyl, mono- or polyunsaturated linear, branched or cyclic 2-23C alkenyl, 6-18C aryl, (1-10C)alkyl(6-18C)aryl or opt. polyunsaturated (2-10C)alkenyl(6-18C)aryl; R3 = H, linear branched or cyclic 1-10C alkyl, mono- or polyunsaturated linear, branched or cyclic 2-10C alkenyl, 6-18C aryl, (1-10C)alkyl(6-18C)aryl or opt. polyunsaturated (2-10C)alkenyl(6-18C)aryl.