公开(公告)号：KR820002229B1

公开(公告)日：1982-12-03

申请号：KR790002933

申请日：1979-08-28

Applicant: HOECHST AG

Inventor： KAEMMERER F ,  SCHLEYERBACH R

IPC: A61K31/42 ,  C07D261/18

Abstract: The antipyretic, analgesic and antiinflammatory compd. I was prepd. by the reaction of 4-trifluoromethylaniline II with 5-methylisoxazole-4-carboxylic acid derivatives III (X = halogen atom, YO or ZO-CO-O group, where, Y=phenyl substituted with fluorine, chlorine, bromine, Iodine, methoxy, ethoxy, nitro or cyano. Z=1-4 carbon number alkyl, phenyl or benzyl.

公开(公告)号：KR800001182B1

公开(公告)日：1980-10-20

申请号：KR770002797

申请日：1977-12-01

Applicant: HOECHST AG

Inventor： HEUBACH G ,  KAEMMERER F ,  SCHLEYERBACH R

IPC: C07D261/10

Abstract: Isoxazole derivs. I; R = mono-, di- or tri-nuclear unsaturated heterocyclic group having C and hetero atom in a ring sub- or unsubstituted by alkyl, alkoxy, halogen, nitro, hydroxyl, carbamoyl; X = halogen, YO group or ZO-CO-O group, Y = halogen, methyl, methoxy, trifluoromethylm nitro, cyano substituted or unsaturated phenyl; Z = C1-4 alkyl, benzyl or phenyl were manufd. by reaction of 5-methyl-isoxazol-4-carboxylic acid derivs. II with unsaturated heterocyclic amine III.

公开(公告)号：ZA7904380B

公开(公告)日：1980-08-27

申请号：ZA7904380

申请日：1979-08-20

Applicant: HOECHST AG

Inventor： GEBERT U ,  ALPERMANN H ,  KAEMMERER F

IPC: A61K31/47 ,  A61P37/08 ,  C07D491/04 ,  C07D491/052 ,  C07D491/16 ,  C07D ,  A61K

CPC classification number: C07D491/04

公开(公告)号：ZA794380B

公开(公告)日：1980-08-27

申请号：ZA794380

申请日：1979-08-20

Applicant: HOECHST AG

Inventor： GEBERT U ,  ALPERMANN H ,  KAEMMERER F

IPC: A61K31/435 ,  A61K31/47 ,  A61P37/08 ,  C07D209/00 ,  C07D221/00 ,  C07D311/00 ,  C07D491/04 ,  C07D491/052 ,  C07D491/147 ,  C07D491/16 ,  C07D ,  A61K