公开(公告)号：ZA891163B

公开(公告)日：1989-10-25

申请号：ZA891163

申请日：1989-02-15

Applicant: HOECHST AG

Inventor： RIPPEL ROBERT ,  ROBERT RIPPEL ,  FLEMMING HANS-WOLFRAM ,  HANS-WOLFRAM FLEMMING ,  RUKWIED MANFRED ,  MANFRED RUKWIED

IPC: C07D333/36 ,  C07D333/38 ,  C07D333/48 ,  C07D

Abstract: Thiophene derivatives with an optionally substituted amino group on the thiophene ring are prepared by dehydrogenation of dihydrothiophenes which are substituted in the same manner as the desired thiophene derivatives, using H2O2, the dihydrothiophenes being reacted in a first reaction step with H2O2 in neutral medium to give the corresponding sulphoxides, and, in the second reaction step, these are then rearranged with acid to give the thiophene derivatives. The dihydrothiophene-1-oxides which are formed in this process as intermediates are novel compounds. They, and equally the thiophene derivatives obtained from them by rearrangement with acid, are intermediates mainly in the crop protection agent sector and pharmaceutical sector.

公开(公告)号：ZA8901163B

公开(公告)日：1989-10-25

申请号：ZA8901163

申请日：1989-02-15

Applicant: HOECHST AG

Inventor： RIPPEL ROBERT ,  ROBERT RIPPEL ,  FLEMMING HANS-WOLFRAM ,  HANS-WOLFRAM FLEMMING ,  RUKWIED MANFRED ,  MANFRED RUKWIED

IPC: C07D333/36 ,  C07D333/38 ,  C07D333/48 ,  C07D

CPC classification number: C07D333/48 ,  C07D333/38