公开(公告)号：DE3583530D1

公开(公告)日：1991-08-29

申请号：DE3583530

申请日：1985-04-04

Applicant: HOECHST AG

Inventor： MAUZ OTTO DR

IPC: C08F8/00 ,  B01J20/26 ,  C07K14/575 ,  C07K16/00 ,  C07K17/08 ,  C08F8/12 ,  C08F20/00 ,  C08F24/00 ,  C08F34/02 ,  C08F291/00 ,  C08F299/00 ,  C08L59/00 ,  C12N11/08 ,  G01N33/545

Abstract: The invention relates to modified polymers based on polyvinylene carbonate and/or polyhydroxymethylene, the modification being effected by particular alkoxylated compounds incorporated into the polymer. These polymers, for the preparation of which, according to the invention, particular dispersion stabilizers are used, are suitable, inter alia, as carriers for biologically active substances or for affinity chromatography.

公开(公告)号：AT65512T

公开(公告)日：1991-08-15

申请号：AT85104099

申请日：1985-04-04

Applicant: HOECHST AG

Inventor： MAUZ OTTO DR

IPC: C08F8/00 ,  B01J20/26 ,  C07K14/575 ,  C07K16/00 ,  C07K17/08 ,  C08F8/12 ,  C08F20/00 ,  C08F24/00 ,  C08F34/02 ,  C08F291/00 ,  C08F299/00 ,  C08L59/00 ,  C12N11/08 ,  G01N33/545

公开(公告)号：DE3766671D1

公开(公告)日：1991-01-24

申请号：DE3766671

申请日：1987-08-26

Applicant: HOECHST AG

Inventor： MAUZ OTTO DR ,  NOETZEL SIEGFRIED DR ,  SAUBER KLAUS DR

IPC: A61K9/16 ,  A61K39/385 ,  A61K39/44 ,  C08F2/14 ,  C08F16/14 ,  C08F20/26 ,  C08F26/00 ,  C08F216/14 ,  C08F220/28 ,  C08F226/00 ,  C08F226/02 ,  C08F271/02 ,  C12N11/08

Abstract: Crosslinked polymers which are produced from monomers containing glycerol carbonate groups, crosslinking monomers and, where appropriate, other monoethylenically unsaturated monomers are composed of principally spherical porous particles and are very suitable as carrier materials for the immobilization of biologically active substances.

公开(公告)号：DE3714276A1

公开(公告)日：1988-11-17

申请号：DE3714276

申请日：1987-04-29

Applicant: HOECHST AG

Inventor： MAUZ OTTO DR ,  NUN EDWIN DIPL CHEM

IPC: B01J20/26 ,  C08F2/16 ,  C08F2/18 ,  C08F2/20 ,  C08F216/38 ,  C08F246/00 ,  C12N11/08 ,  C08F218/08 ,  C08F216/06 ,  B01D15/08 ,  C07K17/08 ,  A61K47/00

Abstract: The invention relates to crosslinked polymers containing porous, bead-form particles based on units of water-soluble monomers or vinyl acetate and/or vinyl alcohol units, crosslinking monomers, acetal group-containing monomers and optionally further monomers which are copolymerisable with one another. These products are, inter alia, particularly hydrolysis-stable and can have high crosslinking densities. The invention furthermore relates to a process for the preparation of these polymers and to their use in chromatography and as carriers for biologically active substances.

公开(公告)号：DE3413904A1

公开(公告)日：1985-10-24

申请号：DE3413904

申请日：1984-04-13

Applicant: HOECHST AG

Inventor： MAUZ OTTO DR

IPC: C08F8/00 ,  B01J20/26 ,  C07K14/575 ,  C07K16/00 ,  C07K17/08 ,  C08F8/12 ,  C08F20/00 ,  C08F24/00 ,  C08F34/02 ,  C08F291/00 ,  C08F299/00 ,  C08L59/00 ,  C12N11/08 ,  G01N33/545 ,  C08F18/24 ,  C08F16/06 ,  C08F18/12 ,  C08F283/06 ,  C07G15/00 ,  C07G11/00 ,  C08L31/00

Abstract: The invention relates to modified polymers based on polyvinylene carbonate and/or polyhydroxymethylene, the modification being effected by particular alkoxylated compounds incorporated into the polymer. These polymers, for the preparation of which, according to the invention, particular dispersion stabilizers are used, are suitable, inter alia, as carriers for biologically active substances or for affinity chromatography.

公开(公告)号：DE1694121A1

公开(公告)日：1971-07-15

申请号：DE1694121

申请日：1966-05-28

Applicant: HOECHST AG

Inventor： MAUZ OTTO DR ,  VETTER HANS-JOACHIM DR ,  REINDL EUGEN DR

IPC: C08K5/17 ,  C08K1/44

公开(公告)号：DE3766689D1

公开(公告)日：1991-01-24

申请号：DE3766689

申请日：1987-08-26

Applicant: HOECHST AG

Inventor： MAUZ OTTO DR ,  NOETZEL SIEGFRIED DR ,  SAUBER KLAUS DR

IPC: A61K39/385 ,  A61K39/44 ,  A61K47/30 ,  C08F2/12 ,  C08F16/14 ,  C08F20/32 ,  C08F26/00 ,  C08F216/14 ,  C08F220/28 ,  C08F220/32 ,  C08F226/00 ,  C08F226/02 ,  C12N11/08 ,  G01N33/545

Abstract: New crosslinked polymer comprises essentially (a) 1-99 wt.% units derived from (meth)acrylic acid glycerine carbonate ester, glycerine carbonate-vinyl ether and/or -allyl ether and (b) 99-1 wt.% units derived from N,N'-divinylethylene- and/or N,N'-divinylpropylene-urea, so that (a)+(b)=100 wt.% and the polymer particles are in spherical condition, with ave. particle size 10-600 micron and ave. pore dia. 5-1000 nm.

公开(公告)号：AT40388T

公开(公告)日：1989-02-15

申请号：AT84114854

申请日：1984-12-06

Applicant: HOECHST AG

Inventor： MAUZ OTTO DR ,  NOETZEL SIEFRIED DR ,  NEUMANN BERNHARD DR

IPC: A61K38/46 ,  A61K39/00 ,  A61K39/44 ,  A61K47/00 ,  A61K47/32 ,  B01D15/08 ,  B01J20/26 ,  B01J20/281 ,  B01J20/285 ,  C08F2/00 ,  C08F2/18 ,  C08F8/00 ,  C08F8/12 ,  C08F16/02 ,  C08F16/32 ,  C08F18/02 ,  C08F22/18 ,  C08F26/00 ,  C08F26/10 ,  C08F216/06 ,  C08F216/12 ,  C08F218/00 ,  C08F218/02 ,  C08F218/04 ,  C08F218/08 ,  C08F226/06 ,  C08J9/224 ,  C12N11/08 ,  G01N30/88 ,  G01N33/543

公开(公告)号：DE3475199D1

公开(公告)日：1988-12-22

申请号：DE3475199

申请日：1984-05-24

Applicant: HOECHST AG

Inventor： NOETZEL SIEGFRIED DR ,  MAUZ OTTO DR ,  SAUBER KLAUS DR

IPC: A61K47/48 ,  B01D15/08 ,  B01J20/26 ,  C08F20/54 ,  C08F220/54 ,  C12N11/08

Abstract: Polymers (A) consist mainly of (1) units derived from monomers of formula (I) and (2) units derived from at least one other monomer. X = H or methyl; R = 1-12C aliphatic hydrocarbyl; Y = hydroxy or amino. The size of the polymer particles is 20-800 microns; they are practically spherical and have mean pore dia. 5-2000 (pref. 10-1000)nm. R = 1-6C aliphatic hydrocarbon, esp. methylene, and Y = hydroxy. A portion of Y may be replaced by spacer gps., esp. epoxy units at 0.1-20 mole % on total polymer. Pref. polymers contain 10-80 (esp. 15-60) mole % (I) units; 20-50 (esp. 30-50) mole % hydrophilic monomer units, and 1-50 (esp. 5-40) mole % crosslinking monomer. Opt. they also include 4-40 (8-20) mole % other non-hydrophilic, non-crosslinking monomers.

公开(公告)号：DE3629177A1

公开(公告)日：1988-03-17

申请号：DE3629177

申请日：1986-08-28

Applicant: HOECHST AG

Inventor： MAUZ OTTO DR ,  NOETZEL SIEGFRIED DR ,  SAUBER KLAUS DR

IPC: A61K39/385 ,  A61K39/44 ,  A61K47/30 ,  C08F2/12 ,  C08F16/14 ,  C08F20/32 ,  C08F26/00 ,  C08F216/14 ,  C08F220/28 ,  C08F220/32 ,  C08F226/00 ,  C08F226/02 ,  C12N11/08 ,  G01N33/545 ,  C08F271/02 ,  C08F265/04 ,  C08F261/06

Abstract: New crosslinked polymer comprises essentially (a) 1-99 wt.% units derived from (meth)acrylic acid glycerine carbonate ester, glycerine carbonate-vinyl ether and/or -allyl ether and (b) 99-1 wt.% units derived from N,N'-divinylethylene- and/or N,N'-divinylpropylene-urea, so that (a)+(b)=100 wt.% and the polymer particles are in spherical condition, with ave. particle size 10-600 micron and ave. pore dia. 5-1000 nm.