公开(公告)号：DE59104720D1

公开(公告)日：1995-03-30

申请号：DE59104720

申请日：1991-06-12

Applicant: HOECHST AG

Inventor： ULBRICH NORBERT ,  HILGENFELD ROLF ,  HAENEL HEINZ ,  SACHSE BURKHARD ,  BRAUN PETER ,  WINK JOACHIM ,  ECKES PETER ,  LOGEMANN JUERGEN ,  SCHELL JOZEF

IPC: A01H5/00 ,  A01N63/00 ,  A01N63/04 ,  A61K38/00 ,  C07K14/00 ,  C07K14/195 ,  C07K14/37 ,  C07K14/41 ,  C07K14/415 ,  C12N5/10 ,  C12N15/09 ,  C12N15/31 ,  C12N15/82 ,  C12P21/02 ,  C12R1/66

Abstract: The polypeptide with the sequence (SEQ ID NO: 1) - Ala-Thr-Tyr-Asn-Gly-Lys-Cys-Tyr-Lys-Lys-Asp- - Asn-Ile-Cys-Lys-Tyr-Lys-Ala-Gln-Ser-Gly-Lys- - Thr-Ala-Ile-Cys-Lys-Cys-Tyr-Val-Lys-Lys-Cys- - Pro-Arg-Asp-Gly-Ala-Lys-Cys-Glu-Phe-Asp-Ser- - Tyr-Lys-Gly-Lys-Cys-Tyr-Cys - can be produced by the fermentation of Aspergillus giganteus and used as an antifungal agent. Expression of this polypeptide gene in plants strongly inhibits the growth of phytopathogenic fungi on the plant.