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    TEST ELEMENT FOR DETECTING AN ANALYTE IN A SAMPLE
    1.
    发明申请
    TEST ELEMENT FOR DETECTING AN ANALYTE IN A SAMPLE 审中-公开
    用于检测样品中分析物的测试元件

    公开(公告)号：WO2010052307A2

    公开(公告)日：2010-05-14

    申请号：PCT/EP2009064758

    申请日：2009-11-06

    Applicant: ROCHE DIAGNOSTICS GMBH ,  HOFFMANN LA ROCHE ,  PETRICH WOLFGANG ,  BEDON-GOMEZ LUIS DAVID

    Inventor： PETRICH WOLFGANG ,  BEDON-GOMEZ LUIS DAVID

    IPC: G01N21/86 ,  G01N33/52

    CPC classification number: G01N21/6428 ,  B01L3/5027 ,  B01L3/502707 ,  B01L3/502746 ,  B01L2200/16 ,  B01L2300/0825 ,  B01L2400/0406 ,  B01L2400/084 ,  G01N21/8483 ,  G01N33/526 ,  G01N33/552

    Abstract: The invention relates to a test element (110) for detecting at least one analyte in a sample (114), in particular for detecting at least one metabolite in a bodily fluid. The test element (110) comprises at least one test field (116) with a test field surface (124). The test field (116) comprises at least one detection reagent (120) that is adapted to undergo a detectable reaction in the presence of the analyte. The test element (110) further comprises at least one distribution element (126) that has at least one distribution surface (130) facing the test field surface (124). Between the distribution surface (130) and the test field surface (124) is at least one capillary gap (132), wherein the capillary gap (132) is adapted to allow a layer of the sample (114) with a layer thickness of no more than 50 µm to form within the capillary gap (132).

    Abstract translation: 本发明涉及用于检测样本（114）中的至少一种分析物的测试元件（110），特别是用于检测体液中的至少一种代谢物。 测试元件（110）包括具有测试场表面（124）的至少一个测试场（116）。 测试区域（116）具有至少一个检测试剂（120），其被设计为在分析物存在下进行可检测的反应。 此外，测试元件（110）具有至少一个分配器元件（126），其具有至少一个分配测试场表面（124）的分配器表面（130）。 分配器表面（130）和测试场表面（124）之间的是至少一个毛细管间隙（132），其中，所述毛细间隙（132）被适配以使得所述毛细管间隙（132）内的是样品（114）有一层厚度的层 不能形成超过50微米。

    FINE-GRAINED FILLER SUBSTANCES FOR PHOTOMETRIC REACTION FILMS
    2.
    发明专利
    FINE-GRAINED FILLER SUBSTANCES FOR PHOTOMETRIC REACTION FILMS 未知

    公开(公告)号：HK1162672A1

    公开(公告)日：2012-08-31

    申请号：HK12103090

    申请日：2012-03-28

    Applicant: HOFFMANN LA ROCHE

    Inventor： KNAPPE WOLFGANG-REINHOLD ,  HILLER BERND ,  LEHR URSULA ,  ZIMMER VOLKER ,  PETRICH WOLFGANG ,  BEDON-GOMEZ LUIS DAVID

    IPC: G01N20060101 ,  B01L20060101

    Abstract: The invention relates to a test element for detecting at least one analyte in a sample, in particular for detecting at least one metabolite in a bodily fluid. The test element comprises at least one test field with a test field surface. The test field comprises at least one detection reagent that is adapted to undergo a detectable reaction in the presence of the analyte. The test element further comprises at least one distribution element that has at least one distribution surface facing the test field surface. Between the distribution surface and the test field surface is at least one capillary gap, wherein the capillary gap is adapted to allow a layer of the sample with a layer thickness of no more than 50 μm to form within the capillary gap.

    FINE-GRAINED FILLER SUBSTANCES FOR PHOTOMETRIC REACTION FILMS
    3.
    发明专利
    FINE-GRAINED FILLER SUBSTANCES FOR PHOTOMETRIC REACTION FILMS 未知

    公开(公告)号：NZ591742A

    公开(公告)日：2012-12-21

    申请号：NZ59174209

    申请日：2009-11-06

    Applicant: HOFFMANN LA ROCHE

    Inventor： KNAPPE WOLFGANG-REINHOLD ,  HILLER BERND ,  LEHR URSULA ,  ZIMMER VOLKER ,  PETRICH WOLFGANG ,  BEDON-GOMEZ LUIS DAVID

    IPC: G01N33/52 ,  B01L3/00 ,  G01N21/86

    Abstract: A diagnostic test element (110) for detecting an analyte in a sample of a bodily fluid (126). The element comprises a test field (116) with at least one detection reagent. The detection reagent is adapted to go through at least one detectable change in the presence of the analyte. The test field comprises a detection layer (118) that comprises the detection reagent and the detection layer comprises particles, wherein 90% of all the particles have a size of less than 10 micrometers. The test field has a loading side for applying the sample and the detection side for detecting a change in the detection reagent. The test field further comprises a removal layer (122) arranged on the side of the detection layer facing the loading side, wherein the removal layer comprise a pigment. The body fluid can be whole blood, the analyte can be glucose and the change in the detection reagent can be an optical change. The particles can be sodium aluminium silicate, aluminium or titanium oxide or a nanoparticulate oxidic matieral of silicon oxide, aluminium oxide and titanium oxide. The pigment can be titanium dioxide, zirconium dioxide, barium titanate, barium zirconate or zirconium silicate.

    TEST ELEMENT FOR DETECTING AN ANALYTE IN A SAMPLE
    5.
    发明专利
    TEST ELEMENT FOR DETECTING AN ANALYTE IN A SAMPLE 未知

    公开(公告)号：HK1162673A1

    公开(公告)日：2012-08-31

    申请号：HK12103091

    申请日：2012-03-28

    Applicant: HOFFMANN LA ROCHE

    Inventor： PETRICH WOLFGANG ,  BEDON-GOMEZ LUIS DAVID

    IPC: G01N20060101 ,  B01L20060101

    Abstract: The invention relates to a test element for detecting at least one analyte in a sample, in particular for detecting at least one metabolite in a bodily fluid. The test element comprises at least one test field with a test field surface. The test field comprises at least one detection reagent that is adapted to undergo a detectable reaction in the presence of the analyte. The test element further comprises at least one distribution element that has at least one distribution surface facing the test field surface. Between the distribution surface and the test field surface is at least one capillary gap, wherein the capillary gap is adapted to allow a layer of the sample with a layer thickness of no more than 50 μm to form within the capillary gap.

    МЕЛКОЗЕРНИСТЫЕ НАПОЛНИТЕЛИ ДЛЯ ФОТОМЕТРИЧЕСКИХ РЕАКТИВНЫХ ПЛЕНОК
    10.
    发明专利
    МЕЛКОЗЕРНИСТЫЕ НАПОЛНИТЕЛИ ДЛЯ ФОТОМЕТРИЧЕСКИХ РЕАКТИВНЫХ ПЛЕНОК 未知

    公开(公告)号：RU2532359C2

    公开(公告)日：2014-11-10

    申请号：RU2011122815

    申请日：2009-11-06

    Applicant: HOFFMANN LA ROCHE

    Inventor： KNAPPE VOL FGANG-RAJNKHOL D ,  KHILLER BERND ,  LER URSULA ,  TSIMMER FOL KER ,  PETRIKH VOL FGANG ,  BEDON-GOMEZ LUIS DAVID

    IPC: G01N33/52 ,  G01N21/78

    Abstract: Изобретениеотноситсяк способуобнаруженияаналитав пробежидкостителапутемиспользованиядиагностическоготестовогоэлемента. Диагностическийтестовыйэлемент (110) дляобнаруженияаналитав пробе (126) жидкоститела, вчастностицельнойкровиобъемомменее 2 микролитров, содержитпоменьшеймереоднотестовоеполе (116) споменьшеймереоднимреагентом-индикатором, гдереагент-индикаторспособенприналичиианалитаиспытыватьпоменьшеймереоднообнаруживаемоеизменение, вчастностиоптическоеизменение. Тестовоеполе (116) включаетпоменьшеймереодиндетекторныйслой (118), содержащийреагент-индикатор, гдедетекторныйслойсодержитчастицы (137). Приэтомпоменьшеймере 90% всехчастиц (137) индикаторногослоя (118) имеютфактическийразмерменее 10 микрон. Диагностическийтестовыйэлемент (110)содержитпоменьшеймереодиннесущийэлемент (112), имеющийпоменьшеймереоднупрозрачнуюобласть (114), гдетестовоеполе (116) своейсторонойдетектирования (120) поменьшеймеречастичнонанесенонапрозрачнуюобласть (114). Обнаруживаемоеизменениеявляетсяоптическидетектируемымизменением, гдедлядетектированияобнаруживаемогоизмененияприменяютоптическийдетекторс пространственнымразрешением. 8 з.п. ф-лы, 8 ил., 1 табл., 2 пр.

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