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    만성 신장 질환의 위험에 대해 피험자를 스크리닝하기 위한 방법들 및 컴퓨터-구현 방법
    1.
    发明公开
    만성 신장 질환의 위험에 대해 피험자를 스크리닝하기 위한 방법들 및 컴퓨터-구현 방법 审中-公开

    公开(公告)号：KR20200135444A

    公开(公告)日：2020-12-02

    申请号：KR20207030180

    申请日：2019-03-22

    Applicant: HOFFMANN LA ROCHE

    Inventor： BUESSER ALEXANDER ,  HUSCHTO TONY ,  PETRICH WOLFGANG ,  RAVIZZA STEFAN ,  SCHNEIDINGER BERND

    IPC: G16H50/70 ,  G16H10/60 ,  G16H50/50

    Abstract: 본개시는만성신장질환 (CKD) 의위험에대해피험자를스크리닝하기위한방법에관한것이고, 그방법은: 피험자에대한복수의마커파라미터들을나타내는마커데이터를수신하는단계로서, 이러한복수의마커파라미터들은, 측정기간동안피험자에대해, 연령값, 크레아티닌의샘플레벨, 및알부민의샘플레벨을나타내는, 상기마커데이터를수신하는단계; 및, 복수의마커파라미터들로부터피험자에대한앓고있는 CKD 의위험을나타내는위험인자를결정하는단계를포함하고, 여기서, 상기결정하는단계는: 알부민의샘플레벨보다더 높게연령값에가중치를부여하는단계, 및, 알부민의샘플레벨보다더 높게크레아티닌의샘플레벨에가중치를부여하는단계를포함한다. 추가로, 만성신장질환 (CKD) 의위험에대해피험자를스크리닝하기위한컴퓨터-구현방법및 피험자를스크리닝하기위한방법이제공된다.

    Fluorescence spectroscopy in absorption medium
    3.
    发明专利
    Fluorescence spectroscopy in absorption medium 审中-公开
    吸收介质中的荧光光谱

    公开(公告)号：JP2007121301A

    公开(公告)日：2007-05-17

    申请号：JP2006290284

    申请日：2006-10-25

    Applicant: F Hoffmann-La Roche Ag ,  エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト

    Inventor： PETRICH WOLFGANG ,  GAESSLER-DIETSCHE CLAUDIA ,  HORN CARINA ,  HEBESTREIT KAI ,  ASFOUR JEAN-MICHEL ,  BARDELANG KLEMENS ,  KOCHERSCHEIDT GERRIT

    IPC: G01N21/64

    CPC classification number: C12Q1/008 ,  C12Q1/26 ,  C12Q1/32 ,  C12Q1/54 ,  G01N33/52 ,  G01N33/66 ,  Y10T436/144444

    Abstract: PROBLEM TO BE SOLVED: To remarkably reduce a dependency with respect to a wavelength of fluorescent excitation light, and to change the fluorescent excitation maximum of a fluorescence emission group. SOLUTION: A detecting medium containing the fluorescence emission group or a precursor of the fluorescence emission group is mixed with an absorber having an absorption spectrum overlapped with a fluorescent excitation range of the fluorescence emission group. A system generated in the detecting medium and comprising the fluorescence emission group and the absorber has a changed effective fluorescent excitation range accompanied with the changed fluorescent excitation maximum. Irradiation by the fluorescent excitation light is executed within the range of the changed excitation maximum. A measured signal obtained from fluorescence emission measurement indicates only the low dependency with respect to the wavelength of the excitation light. Further, an inexpensive light source such as UV LEDs may be usable because of the changed wave length of the excitation light. COPYRIGHT: (C)2007,JPO&INPIT

    Abstract translation: 要解决的问题：显着降低相对于荧光激发光的波长的依赖性，并且改变荧光发射基团的荧光激发最大值。 解决方案：将含有荧光发射基团或荧光发射基团的前体的检测介质与具有与荧光发射基团的荧光激发范围重叠的吸收光谱的吸收剂混合。 在检测介质中产生并且包括荧光发射基团和吸收体的系统具有伴随改变的荧光激发最大值的改变的有效荧光激发范围。 通过荧光激发光的照射在变化的激发最大值的范围内进行。 从荧光发射测量获得的测量信号仅表示相对于激发光的波长的低依赖性。 此外，由于激发光的波长变化，可以使用诸如UV LED的便宜的光源。 版权所有（C）2007，JPO＆INPIT

    TEST ELEMENT FOR DETECTING AN ANALYTE IN A SAMPLE
    4.
    发明申请
    TEST ELEMENT FOR DETECTING AN ANALYTE IN A SAMPLE 审中-公开
    用于检测样品中分析物的测试元件

    公开(公告)号：WO2010052307A2

    公开(公告)日：2010-05-14

    申请号：PCT/EP2009064758

    申请日：2009-11-06

    Applicant: ROCHE DIAGNOSTICS GMBH ,  HOFFMANN LA ROCHE ,  PETRICH WOLFGANG ,  BEDON-GOMEZ LUIS DAVID

    Inventor： PETRICH WOLFGANG ,  BEDON-GOMEZ LUIS DAVID

    IPC: G01N21/86 ,  G01N33/52

    CPC classification number: G01N21/6428 ,  B01L3/5027 ,  B01L3/502707 ,  B01L3/502746 ,  B01L2200/16 ,  B01L2300/0825 ,  B01L2400/0406 ,  B01L2400/084 ,  G01N21/8483 ,  G01N33/526 ,  G01N33/552

    Abstract: The invention relates to a test element (110) for detecting at least one analyte in a sample (114), in particular for detecting at least one metabolite in a bodily fluid. The test element (110) comprises at least one test field (116) with a test field surface (124). The test field (116) comprises at least one detection reagent (120) that is adapted to undergo a detectable reaction in the presence of the analyte. The test element (110) further comprises at least one distribution element (126) that has at least one distribution surface (130) facing the test field surface (124). Between the distribution surface (130) and the test field surface (124) is at least one capillary gap (132), wherein the capillary gap (132) is adapted to allow a layer of the sample (114) with a layer thickness of no more than 50 µm to form within the capillary gap (132).

    Abstract translation: 本发明涉及用于检测样本（114）中的至少一种分析物的测试元件（110），特别是用于检测体液中的至少一种代谢物。 测试元件（110）包括具有测试场表面（124）的至少一个测试场（116）。 测试区域（116）具有至少一个检测试剂（120），其被设计为在分析物存在下进行可检测的反应。 此外，测试元件（110）具有至少一个分配器元件（126），其具有至少一个分配测试场表面（124）的分配器表面（130）。 分配器表面（130）和测试场表面（124）之间的是至少一个毛细管间隙（132），其中，所述毛细间隙（132）被适配以使得所述毛细管间隙（132）内的是样品（114）有一层厚度的层 不能形成超过50微米。

    SUBCUTANEOUS ANALYTE SENSOR
    5.
    发明申请
    SUBCUTANEOUS ANALYTE SENSOR 审中-公开
    SUBCUTANEOUS分析仪传感器

    公开(公告)号：WO02074161A3

    公开(公告)日：2003-07-24

    申请号：PCT/EP0202960

    申请日：2002-03-18

    Applicant: ROCHE DIAGNOSTICS GMBH ,  HOFFMANN LA ROCHE

    Inventor： ESSENPREIS MATTHIAS ,  GERBER MARTIN ,  PETRICH WOLFGANG

    IPC: G01N21/01 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1459 ,  G01N21/41 ,  G01N21/43

    CPC classification number: A61B5/1459 ,  A61B5/14532

    Abstract: Assembly and method for measuring the concentration of an analyte in a biological matrix. The assembly includes an implantatble optical-sensing element (100) that comprises a body (104), and a membrane (110) mounted on the body in a manner such that the membrane and the body define a cavity. The membrane is permeable to the analyte, but is permeable to background species in the biological matrix. A refractive element (115) is positioned in the cavity. A light source (106) transmits light of a first intensity onto the refractive element, and a light detector (106) receives light of a second intensity that is reflected from the cavity. A controller device optically coupled to the detector compares the first and second light intensities, and relates the intensities to analyte concentration.

    Abstract translation: 用于测量生物基质中分析物浓度的装配和方法。 组件包括植入式光学感测元件（100），其包括主体（104）和以使得膜和主体限定空腔的方式安装在主体上的膜（110）。 膜对分析物是可渗透的，但是对生物基质中的背景物质是可渗透的。 折射元件（115）位于空腔中。 光源（106）将第一强度的光透射到折射元件上，并且光检测器（106）接收从空腔反射的第二强度的光。 光耦合到检测器的控制器设备比较第一和第二光强度，并将强度与分析物浓度相关联。

    System for detection of an analyte in a body fluid
    9.
    发明专利
    System for detection of an analyte in a body fluid 未知

    公开(公告)号：AU2013202929B2

    公开(公告)日：2016-05-26

    申请号：AU2013202929

    申请日：2013-04-08

    Applicant: HOFFMANN LA ROCHE

    Inventor： WONG DANIEL ,  PATEL PAUL ,  PETRICH WOLFGANG ,  VRANCIC CHRISTIAN

    IPC: A61B5/00 ,  A61B5/151 ,  G01N35/00 ,  G01N35/10

    Abstract: C:\NRPortbl\DCC\KMH\5047988_1.DOC - 8/4/13 Abstract A system (110) is proposed for detection of at least one analyte in a body 5 fluid, in particular for detection of blood glucose. The system (110) is designed to generate a sample (130) of the body fluid and to transfer at least some of the sample to at least one test element (128), in particular a test panel (129). The system (110) is designed such that a time period between the generation of the sample (130) and the application to the test element (128) is less than 1 s, 10 preferably less than 500 ms. (Figure 1)

    ANALYTICAL APPARATUS FOR DETECTING AT LEAST ONE ANALYTE IN A SAMPLE
    10.
    发明专利
    ANALYTICAL APPARATUS FOR DETECTING AT LEAST ONE ANALYTE IN A SAMPLE 未知

    公开(公告)号：CA2850693C

    公开(公告)日：2016-04-19

    申请号：CA2850693

    申请日：2012-11-12

    Applicant: HOFFMANN LA ROCHE

    Inventor： PETRICH WOLFGANG ,  HORN CARINA ,  STEINKE NELLI ,  RINGEMANN CHRISTIAN ,  VON KETTELER ALEXA

    IPC: A61B5/145 ,  G01N21/64 ,  G01N35/00

    Abstract: An analytical apparatus (130) for detecting at least one analyte in a sample (126), in particular for detecting blood glucose, is proposed, - where the analytical apparatus (130) is equipped to carry out at least one analyte measurement, where in the analyte measurement at least a property changeable by presence of the analyte at least of a test chemical (119) of a test element (110) is recorded, in particular an electrical and/or optical property, and - where the analytical apparatus (130) is furthermore equipped to carry out at least a quality measurement on the test chemical (119), where in the quality measurement at least an intrinsic luminescence of the test chemical (119) is recorded and from the intrinsic luminescence a conclusion is drawn on a quality of the test chemical (119), in particular a degradation.

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