公开(公告)号：US20240183828A1

公开(公告)日：2024-06-06

申请号：US18285286

申请日：2022-04-27

Applicant: Hitachi High-Tech Corporation

Inventor： Shota AOYAGI ,  Daisuke AKIEDA ,  Sho IWASA

IPC: G01N30/86 ,  G01N30/32

CPC classification number: G01N30/8665 ,  G01N30/32

Abstract: A liquid chromatography analyzer acquires a first output value P1 of a pressure sensor measured by opening a flow passage to the atmosphere or by installing, in a column installation portion, a first column that is not filled with a filler, acquires a second output value P2 of the pressure sensor measured by installing a second column having a known pressure resistance Ps in the column installation portion, and updates a gain of the pressure sensor by using the first output value P1 and the second output value P2. Thus, inspection and adjustment of the pressure sensor can be easily performed without adding a complicated mechanism.

公开(公告)号：US20230384271A1

公开(公告)日：2023-11-30

申请号：US18032717

申请日：2021-10-12

Applicant: Hitachi High-Tech Corporation

Inventor： Nobuhiro TSUKADA ,  Daisuke AKIEDA ,  Sho IWASA ,  Yusuke YOTA ,  Yuichiro HASHIMOTO

IPC: G01N30/32 ,  F04B23/06 ,  F04B49/06 ,  F04B51/00

CPC classification number: G01N30/32 ,  F04B23/06 ,  F04B49/06 ,  F04B51/00 ,  G01N2030/326

Abstract: Provided is a technology for reducing the capacity of a liquid feeding pump and enabling liquid feeding with little pulsation. A liquid feeding pump according to the present disclosure is provided with: a first plunger pump having a first plunger; a second plunger pump having a second plunger and connected in series with the first plunger pump; a pressure sensor disposed downstream of the second plunger pump; and a control unit that accepts the input of a liquid discharge pressure measured by the pressure sensor and that controls the driving of the first plunger and the driving of the second plunger. The control unit calculates the rate of change in the pressure of the liquid on the basis of the past compression distances of the plunger for when the liquid was compressed by the first plunger pump and the pressure at the completion of compression, predicts the compression distance of the first plunger on the basis of the rate of change in pressure and the present discharge pressure, and determines the timing at which the compression performed by the first plunger will be completed on the basis of the predicted compression distance.

公开(公告)号：US20230332586A1

公开(公告)日：2023-10-19

申请号：US17791593

申请日：2020-11-05

Applicant: Hitachi High-Tech Corporation

Inventor： Nobuhiro TSUKADA ,  Daisuke AKIEDA ,  Yuichiro HASHIMOTO ,  Sho IWASA ,  Yusuke YOTA

IPC: F04B23/06 ,  F04B49/06 ,  F04B49/08 ,  F04B49/20 ,  G01N30/32

CPC classification number: F04B23/06 ,  F04B49/065 ,  F04B49/08 ,  F04B49/20 ,  G01N30/32 ,  G01N2030/326

Abstract: The present invention provides a technique that enables liquid feeding with small pulsation by reducing the volume of a liquid feeding pump. Disclosed is a liquid feeding pump comprising: a first plunger pump that has a first plunger; a second plunger pump that has a second plunger and is connected to the first plunger pump in series; a pressure sensor that is disposed on the downstream side of the second plunger pump; and a control unit that accepts an input of the discharge pressure of a liquid measured by the pressure sensor to control driving of the first plunger and driving of the second plunger, wherein when the first plunger pump compresses the liquid, the control unit drives the first plunger at a first speed, and then decreases the speed to a second speed slower than the first speed before the compression is completed, and wherein the control unit discharges the liquid from the second plunger pump by driving the second plunger in parallel with the driving of the first plunger.

公开(公告)号：US20250035096A1

公开(公告)日：2025-01-30

申请号：US18715904

申请日：2022-11-14

Applicant: Hitachi High-Tech Corporation

Inventor： Nobuhiro TSUKADA ,  Daisuke KANAI ,  Sho IWASA ,  Yushi HARADA ,  Yusuke YOTA

IPC: F04B23/06 ,  F04B51/00

Abstract: A liquid delivery pump delivers a liquid with high flow rate accuracy in consideration of solvent expansion, pressure dependent leakage of the solvent, and flow rate dependent leakage of the solvent. A liquid delivery pump includes first and second plunger pumps connected together, having respective first and second plungers. A pressure sensor measures a liquid delivery pressure (P2) from the second plunger pump, and a controller controls the driving of the first and second plungers. The controller obtains a moving speed (v1) of the first plunger and a moving speed (v2) of the second plunger using a parameter (C1, C0) depending on the liquid delivery pressures (P1, P2), the liquid delivery pressure, and a target flow rate of the liquid. The parameter (C1, C0) is a parameter of an expression representing a relationship between the liquid delivery pressure (P2) and a flow rate (Q0) of the liquid.

公开(公告)号：US20240019347A1

公开(公告)日：2024-01-18

申请号：US18036920

申请日：2021-12-06

Applicant: HITACHI HIGH-TECH CORPORATION

Inventor： Sho IWASA ,  Jun MAEDA

IPC: G01N1/40 ,  G01N35/10

CPC classification number: G01N1/4022 ,  G01N35/1009 ,  G01N2001/4027 ,  G01N2035/00356

Abstract: An evaporative concentration mechanism is achieved, which accurately evaporates and concentrates a small quantity of a sample liquid for a short period of time, regardless of the composition of the sample liquid or the surrounding environmental conditions. The evaporative concentration mechanism includes a container that accommodates a sample liquid; a heating unit that heats the container; a liquid level sensor that detects a liquid level height of the sample liquid accommodated in the container; and a control unit that controls a temperature of the heating unit, in which the control unit controls the temperature of the heating unit based on a liquid level of the sample liquid detected by the liquid level sensor. Accordingly, a small quantity of a sample liquid can be accurately evaporated and concentrated for a short period of time, regardless of the composition of the sample liquid or the surrounding environmental conditions.

公开(公告)号：US20240011955A1

公开(公告)日：2024-01-11

申请号：US18037808

申请日：2021-12-07

Applicant: Hitachi High-Tech Corporation

Inventor： Yusuke SHIMIZU ,  Takayuki SUGIME ,  Sho IWASA

IPC: G01N30/60 ,  B01D15/18

CPC classification number: G01N30/60 ,  B01D15/18 ,  G01N2030/027

Abstract: A column connection method of a liquid chromatograph and a liquid chromatograph capable of keeping a mistakenly installed column by an operator as an unused column are provided. The column connection method of the liquid chromatograph includes: a first step of installing a column at a column installation part and obtaining a first reading result by reading identification information of the column before connecting the column with an analysis flow path; and a second step of connecting the column with the analysis flow path and obtaining a second reading result by reading identification information of the column, in which the first reading result is compared with the second reading result to judge identity of the column.