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    BLOOD PROCESSING APPARATUS
    3.
    发明专利
    BLOOD PROCESSING APPARATUS 未知

    公开(公告)号：CA990255A

    公开(公告)日：1976-06-01

    申请号：CA159070

    申请日：1972-12-13

    Applicant: IBM

    Inventor： JONES ALAN L ,  JUDSON GEORGE T ,  KELLOGG ROBERT M ,  KRUGER VICTOR R

    IPC: A61M1/02 ,  A61M1/00 ,  A61M1/36 ,  A61M5/148 ,  B04B5/04

    Abstract: Apparatus for processing blood, and particularly for washing blood cells, including a centrifuge head in which is arranged a flexible blood container connected by a rotating seal to tubing which permits the entrance and exit of wash liquid and supernatant. The flow of liquid in the tubing is controlled by valve arrangements which are operable to permit the entrance of wash liquid and removal of supernatant liquid. The flexible container fits over a flexible membrane also arranged inside the centrifuge head about a solid central core. The volume defined by this membrane and the core communicates via a passage in the core with a fluid reservoir by means of a control pump which allows fluid to enter and exit from the volume defined by the membrane. During operation the unwashed blood may be entered into the container or blood bag before or after the bag is placed in the centrifuge. The centrifuge is spun until cells have settled against the outside wall at which time the valve arrangements and the control pump are activated such that fluid is pumped into the centrifuge under the volume defined by the membrane thereby forcing a supernatant to flow out to a collect container. The centrifuge is then stopped and the wash solution enters the blood container through another valve arrangement, thereby allowing the removal of fluid from the volume inside the flexible membrane. Removal of the wash liquid is accomplished by the same process of removal as the removal of supernatant previously described. Provisions are made for electrical control of all the operations including an agitate operation in which the centrifuge is spun in alternate directions for only a few revolutions or goes through alternate accelerate-decelerate cycles while rotating in the same direction to thereby agitate the material in the blood bag or flexible container during the time that a wash solution is entering. The circuit arrangements are such that a high degree of flexibility in the programming of the various operations can be obtained.

    FLUID CONTAINER
    5.
    发明专利
    FLUID CONTAINER 未知

    公开(公告)号：CA971143A

    公开(公告)日：1975-07-15

    申请号：CA162350

    申请日：1973-01-24

    Applicant: IBM

    Inventor： JONES ALAN L ,  JUDSON GEORGE T

    IPC: G01N33/48 ,  A61J1/00 ,  A61J1/05 ,  B01J19/00 ,  B01L3/00 ,  B04B1/00 ,  B04B5/04 ,  G01N1/28 ,  G01N35/00

    Abstract: 1374050 Centrifuge container INTERNATIONAL BUSINESS MACHINES CORP 29 Dec 1972 [28 Jan 1972] 60155/72 Heading B2P A fluid container, e.g. for washing and centrifuging blood, is made of flexible material and comprises an annular outer portion forming a toroid when filled, a central hub portion 11 connected to the portion by a plurality of radial channels 7, and an inlet/ outlet tubing connector (not shown) in the central hub portion. The container is formed from two circular pieces 3a, 3b of P.V.C. which are sealed together at their periphery, e.g. by application of heat and pressure and also at sector-shaped areas 5 to form the channels 7. Openings 9 are provided through the areas 5 and in operation fit over projections on a centrifuge rotor to anchor the container during rotation. Fluid may be supplied to, or withdrawn from, the container during centrifuging through the hub portion by way of the tubing connector which is provided with a rotating seal. An outlet tube 15 having inner and outer caps 17, 19 is provided to extract processed blood after centrifuging, while the bag is suspended by a split portion 21, by removing the cap 19 and thrusting a cannula of a tubing set into the tube 15 and forcing off the cap 17. A sampling tube 25 may be provided with one end attached to the periphery of the bag and the other end sealed.

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