DIAGNOSIS OF FELINE IMMUNODEFICIENCY VIRUS INFECTION USING ENV/GAG POLYPEPTIDE MARKER

    公开(公告)号:JP2000002707A

    公开(公告)日:2000-01-07

    申请号:JP13582899

    申请日:1999-05-17

    Applicant: IDEXX LAB INC

    Abstract: PROBLEM TO BE SOLVED: To provide a method and an apparatus for diagnosing the presence of a feline immune deficiency. SOLUTION: In this method for deciding whether a feline is infected by a feline immunodeficiency virus(FIV), a biological sample of the feline is given, the sample is brought into contact with an antibody binding capture composition containing (i) a first enhanced capture polypeptide containing an immunogeneic fragment of an FIVgag precursor p55 and (ii) a second enhanced capture polypeptide containing an immunogeneic fragment of an FIVenv precursor gp130, and the reaction of the antibody in the sample is detected by using the capture composition. Here, the generation of the reaction represents that the feline is infected with the FIV.

    METHOD AND DEVICE FOR DETECTING FELINE IMMUNODEFICIENCY VIRUS
    2.
    发明申请
    METHOD AND DEVICE FOR DETECTING FELINE IMMUNODEFICIENCY VIRUS 审中-公开
    用于检测FELINE免疫缺陷病毒的方法和装置

    公开(公告)号:WO2005080939A3

    公开(公告)日:2005-10-06

    申请号:PCT/US2005004924

    申请日:2005-02-16

    Abstract: A method and device for determining a feline immunodeficiency virus infection or vaccination in an animal. The method includes contacting a biological sample from a felid with various FIV polypeptides and determining the binding of antibodies in the sample to the polypeptides. The determination of whether an animal is infected with FIV or has been vaccinated against FIV can be determined by measuring the animal's immune response to an FIV env polypeptide. A device for detecting FIV antibodies is provided.

    Abstract translation: 用于确定动物的猫免疫缺陷病毒感染或疫苗接种的方法和装置。 该方法包括使来自felid的生物样品与各种FIV多肽接触并确定样品中的抗体与多肽的结合。 通过测量动物对FIV env多肽的免疫应答,可以确定动物是否感染FIV或已经接种FIV疫苗。 提供了一种用于检测FIV抗体的装置。

    DETECTION OF ANALYTES IN FECAL SAMPLES
    3.
    发明申请
    DETECTION OF ANALYTES IN FECAL SAMPLES 审中-公开
    检测FECAL样品中的分析物

    公开(公告)号:WO2004097412A3

    公开(公告)日:2005-02-17

    申请号:PCT/US2004012646

    申请日:2004-04-23

    CPC classification number: G01N33/5308

    Abstract: A method for detecting a parasitic worm infection of the digestive tract of a mammal. The method includes detecting the binding of a worm antibody to a worm antigen present in the soluble portion of a fecal sample of infected mammals.

    Abstract translation: 一种用于检测哺乳动物的消化道的寄生虫感染的方法。 该方法包括检测蠕虫抗体与存在于受感染哺乳动物的粪便样品的可溶性部分中的蠕虫抗原的结合。

    PROCEDIMIENTO Y DISPOSITIVO PARA DETECTAR EL VIRUS DE LA INMUNODEFICIENCIA FELINA.

    公开(公告)号:ES2327340T3

    公开(公告)日:2009-10-28

    申请号:ES04783703

    申请日:2004-09-10

    Applicant: IDEXX LAB INC

    Abstract: Un procedimiento in vitro para distinguir entre (a) los félidos que han sido infectados de manera natural con el VIF o félidos vacunados con la vacuna entera del VIF muerto producida a partir de múltiples cepas que tienen diferentes subtipos, y en una fase de inicial transitoria de producción de anticuerpos y (b) los félidos vacunados con dicha vacuna entera del VIF muerto y después de una fase inicial transitoria de producción de anticuerpos o los félidos que no han sido infectados, procedimiento que comprende las etapas de: poner en contacto una primera muestra biológica que ha sido tomada de un félido con un polipéptido env del VIF para formar un primer complejo de anticuerpo-polipéptido env en presencia de anticuerpos frente a env del VIF, si los hay, en la primera muestra biológica; detectar la presencia o la ausencia del primer complejo; determinar que el félido: (i) está infectado de manera natural con el VIF o vacunado y en la fase inicial transitoria de producción de anticuerpos, si el primer complejo está presente; o (ii) no está infectado con el VIF ni vacunado y después de la fase inicial transitoria de producción de anticuerpos, si el primer complejo está ausente.

    8.
    发明专利
    未知

    公开(公告)号:DE69909897T2

    公开(公告)日:2004-05-27

    申请号:DE69909897

    申请日:1999-05-14

    Applicant: IDEXX LAB INC

    Abstract: We disclose methods for determining whether a feline is infected with feline immunodeficiency virus ("FIV"). The methods involve the use of an antibody-binding composition that includes two enhanced polypeptides, one containing an immunogenic fragment of the FIV gag precursor p55 and the other containing an immunogenic fragment of the FIV env precursor gp130. Also disclosed are devices for practising these methods.

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