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公开(公告)号：AU2016254150B2
公开(公告)日：2021-09-30
申请号：AU2016254150
申请日：2016-04-29
Applicant: IDEXX LAB INC
Inventor： QUINN JOHN JOSEPH , YERRAMILLI MURTHY VSN
IPC: G01N33/68 , G01N33/493
Abstract: The invention provides methods and compositions for the detection of specific isoforms of clusterin.
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公开(公告)号：MX388832B
公开(公告)日：2025-03-20
申请号：MX2017013729
申请日：2017-10-25
Applicant: IDEXX LAB INC
Inventor： QUINN JOHN JOSEPH , VSN YERRAMILLI MURTHY
IPC: G01N33/68 , G01N33/493
Abstract: La presente invención se refiere a un método para detectar clusterina específica de los riñones, caracterizado porque comprende (a) poner en contacto una muestra con (i) uno o más anticuerpo o fragmentos de unión a antígenos de los mismos que se unen específicamente a clusterina y (ii) una o más moléculas que se unen específicamente a porciones de carbohidratos de clusterina específica de los riñones y que no se unen específicamente a porciones de carbohidratos de isoformas de clusterina transportada por la sangre, no específica de los riñones, y (b) detectar complejos de clusterina específica de los riñones, uno o más de los anticuerpo o fragmentos de unión a antígeno de los mismos que se unen específicamente a clusterina, y una o más de las moléculas que se unen específicamente a porciones de carbohidratos de clusterina específicamente de los riñones y que no se unen específicamente a porciones de carbohidratos de isoformas de clusterina transportadas por la sangre, no específicas de los riñones.
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公开(公告)号：NZ736200A
公开(公告)日：2021-11-26
申请号：NZ73620016
申请日：2016-04-29
Applicant: IDEXX LAB INC
Inventor： YERRAMILLI MURTHY , QUINN JOHN JOSEPH
IPC: G01N33/68 , G01N33/493
Abstract: The invention provides methods and compositions for the detection of specific isoforms of clusterin.
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公开(公告)号：AU2016254226C1
公开(公告)日：2022-11-24
申请号：AU2016254226
申请日：2016-05-02
Applicant: IDEXX LAB INC
Inventor： YERRAMILLI MAHALAKSHMI , OBARE EDWARD , QUINN JOHN JOSEPH , YERRAMILLI MURTHY VSN
IPC: G01N33/48 , C07C229/08 , C07C279/12 , G01N33/50 , G01N33/68
Abstract: Methods for determining renal function in an animal subject, the method including measuring the concentration of β-aminoisobutyric acid (β-amino isobutyrate) (BAIB) in patients samples and determining the presence, likelihood, or progression of kidney disease as a result of structural damage, or mortality associated with kidney disease. The methods also include measuring the concentration of BAIB in combination is symmetrical dimethyl arginine (SDMA) and determining kidney disease based upon the concentrations of BAIB and SDMA in the samples. Anti-BAIB antibodies, BAIB-conjugates, and assay methods using the antibodies and conjugates are also disclosed.
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5.发明专利
公开(公告)号：AU2017225758A1
公开(公告)日：2018-08-30
申请号：AU2017225758
申请日：2017-03-02
Applicant: IDEXX LAB INC
Inventor： YERRAMILLI MAHALAKSHMI , FARACE GIOSI , QUINN JOHN JOSEPH , YERRAMILLI MURTHY V S N
Abstract: The disclosure provides compositions and methods for the detection of renal disease and periodontal disease in mammals.
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Patent Agency Ranking
公开(公告)号：AU2016254226A1
公开(公告)日：2017-11-09
申请号：AU2016254226
申请日：2016-05-02
Applicant: IDEXX LAB INC
Inventor： YERRAMILLI MAHALAKSHMI , OBARE EDWARD , QUINN JOHN JOSEPH , YERRAMILLI MURTHY VSN
IPC: G01N33/48 , C07C229/08 , C07C279/12 , G01N33/50 , G01N33/68
Abstract: Methods for determining renal function in an animal subject, the method including measuring the concentration of β-aminoisobutyric acid (β-amino isobutyrate) (BAIB) in patients samples and determining the presence, likelihood, or progression of kidney disease as a result of structural damage, or mortality associated with kidney disease. The methods also include measuring the concentration of BAIB in combination is symmetrical dimethyl arginine (SDMA) and determining kidney disease based upon the concentrations of BAIB and SDMA in the samples. Anti-BAIB antibodies, BAIB-conjugates, and assay methods using the antibodies and conjugates are also disclosed.
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公开(公告)号：DK3289363T3
公开(公告)日：2022-02-28
申请号：DK16724520
申请日：2016-04-29
Applicant: IDEXX LAB INC
Inventor： QUINN JOHN JOSEPH , YERRAMILLI MURTHY VSN
IPC: G01N33/68 , G01N33/493
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8.发明专利
公开(公告)号：ZA201806418B
公开(公告)日：2019-07-31
申请号：ZA201806418
申请日：2018-09-26
Applicant: IDEXX LAB INC
Inventor： YERRAMILLI MAHALAKSHMI , FARACE GIOSI , QUINN JOHN JOSEPH , YERRAMILLI MURTHY V S N
Abstract: The disclosure provides compositions and methods for the detection of renal disease and periodontal disease in mammals.
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公开(公告)号：CA2983828A1
公开(公告)日：2016-11-03
申请号：CA2983828
申请日：2016-04-29
Applicant: IDEXX LAB INC
Inventor： QUINN JOHN JOSEPH , YERRAMILLI MURTHY VSN
IPC: G01N33/68 , G01N33/493
Abstract: The invention provides methods and compositions for the detection of specific isoforms of clusterin.
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公开(公告)号：AU2016254226B2
公开(公告)日：2022-05-26
申请号：AU2016254226
申请日：2016-05-02
Applicant: IDEXX LAB INC
Inventor： YERRAMILLI MAHALAKSHMI , OBARE EDWARD , QUINN JOHN JOSEPH , YERRAMILLI MURTHY VSN
IPC: G01N33/48 , C07C229/08 , C07C279/12 , G01N33/50 , G01N33/68
Abstract: Methods for determining renal function in an animal subject, the method including measuring the concentration of β-aminoisobutyric acid (β-amino isobutyrate) (BAIB) in patients samples and determining the presence, likelihood, or progression of kidney disease as a result of structural damage, or mortality associated with kidney disease. The methods also include measuring the concentration of BAIB in combination is symmetrical dimethyl arginine (SDMA) and determining kidney disease based upon the concentrations of BAIB and SDMA in the samples. Anti-BAIB antibodies, BAIB-conjugates, and assay methods using the antibodies and conjugates are also disclosed.
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