公开(公告)号：CA2256592C

公开(公告)日：2010-06-01

申请号：CA2256592

申请日：1997-06-16

Applicant: IMARX PHARMACEUTICAL CORP

Inventor： UNGER EVAN C ,  MATSUNAGA TERRY O ,  FRITZ THOMAS A ,  RAMASWAMI VARADA RAJAN

IPC: A61K49/00 ,  A61M5/00 ,  A61B8/00 ,  A61B8/13 ,  A61K9/127 ,  A61K49/22 ,  A61K51/02 ,  A61M5/14

Abstract: Methods for providing an image of an internal region of a patient. Embodiments of the methods involve administering to the patient a contrast agent which comprises a vesicle composition comprising, in an aqueous carrier, a gas or gaseous precursor and vesicles comprising lipids, proteins or polymers. The patient is scanned using diagnostic imaging, such as ultrasound, to obtain a visible image of the region. The contrast agent is administered to the patient at a rate to substantially eliminate diagnostic artifacts in the image. The methods are particularly useful for diagnosing the presence of any diseased tissue in the patient.

公开(公告)号：AU3313197A

公开(公告)日：1998-01-07

申请号：AU3313197

申请日：1997-06-16

Applicant: IMARX PHARMACEUTICAL CORP

Inventor： UNGER EVAN C ,  MATSUNAGA TERRY O ,  FRITZ THOMAS A ,  RAMASWAMI VARADA RAJAN

IPC: A61M5/00 ,  A61B8/00 ,  A61K49/00 ,  A61K49/22 ,  A61K51/02 ,  A61B5/055

Abstract: Methods for providing an image of an internal region of a patient. Embodiments of the methods involve administering to the patient a contrast agent which comprises a vesicle composition comprising, in an aqueous carrier, a gas or gaseous precursor and vesicles comprising lipids, proteins or polymers. The patient is scanned using diagnostic imaging, such as ultrasound, to obtain a visible image of the region. The contrast agent is administered to the patient at a rate to substantially eliminate diagnostic artifacts in the image. The methods are particularly useful for diagnosing the presence of any diseased tissue in the patient.

公开(公告)号：HK1019699A1

公开(公告)日：2000-02-25

申请号：HK99104828

申请日：1999-10-27

Applicant: IMARX PHARMACEUTICAL CORP

Inventor： UNGER EVAN C ,  MATSUNAGA TERRY O ,  FRITZ THOMAS A ,  RAMASWAMI VARADA RAJAN

IPC: A61M5/00 ,  A61B20090101 ,  A61B8/00 ,  A61K49/00 ,  A61K49/22 ,  A61K51/02

Abstract: Methods for providing an image of an internal region of a patient. Embodiments of the methods involve administering to the patient a contrast agent which comprises a vesicle composition comprising, in an aqueous carrier, a gas or gaseous precursor and vesicles comprising lipids, proteins or polymers. The patient is scanned using diagnostic imaging, such as ultrasound, to obtain a visible image of the region. The contrast agent is administered to the patient at a rate to substantially eliminate diagnostic artifacts in the image. The methods are particularly useful for diagnosing the presence of any diseased tissue in the patient.

公开(公告)号：CA2256592A1

公开(公告)日：1997-12-24

申请号：CA2256592

申请日：1997-06-16

Applicant: IMARX PHARMACEUTICAL CORP

Inventor： UNGER EVAN C ,  RAMASWAMI VARADA RAJAN ,  FRITZ THOMAS A ,  MATSUNAGA TERRY O

IPC: A61M5/00 ,  A61B8/00 ,  A61K49/00 ,  A61K49/22 ,  A61K51/02 ,  A61K9/127 ,  A61B8/13 ,  A61M5/14

Abstract: Methods for providing an image of an internal region of a patient. Embodiments of the methods involve administering to the patient a contrast agent which comprises a vesicle composition comprising, in an aqueous carrier, a gas or gaseous precursor and vesicles comprising lipids, proteins or polymers. The patient is scanned using diagnostic imaging, such as ultrasound, to obtain a visible image of the region. The contrast agent is administered to the patient at a rate to substantially eliminate diagnostic artifacts in the image. The methods are particularly useful for diagnosing the presence of any diseased tissue in the patient.

公开(公告)号：DE69738964D1

公开(公告)日：2008-10-16

申请号：DE69738964

申请日：1997-06-16

Applicant: IMARX PHARMACEUTICAL CORP

Inventor： UNGER EVAN C ,  MATSUNAGA TERRY O ,  FRITZ THOMAS A ,  RAMASWAMI VARADA RAJAN

IPC: A61B5/055 ,  A61M5/00 ,  A61B8/00 ,  A61K49/00 ,  A61K49/22 ,  A61K51/02

Abstract: Methods for providing an image of an internal region of a patient. Embodiments of the methods involve administering to the patient a contrast agent which comprises a vesicle composition comprising, in an aqueous carrier, a gas or gaseous precursor and vesicles comprising lipids, proteins or polymers. The patient is scanned using diagnostic imaging, such as ultrasound, to obtain a visible image of the region. The contrast agent is administered to the patient at a rate to substantially eliminate diagnostic artifacts in the image. The methods are particularly useful for diagnosing the presence of any diseased tissue in the patient.

公开(公告)号：AU6188501A

公开(公告)日：2001-10-18

申请号：AU6188501

申请日：2001-08-17

Applicant: IMARX PHARMACEUTICAL CORP

Inventor： UNGER EVAN C ,  MATSUNAGA TERRY O ,  FRITZ THOMAS A ,  RAMASWAMI VARADA RAJAN

IPC: A61B8/13

公开(公告)号：AU733492B2

公开(公告)日：2001-05-17

申请号：AU3313197

申请日：1997-06-16

Applicant: IMARX PHARMACEUTICAL CORP

Inventor： UNGER EVAN C ,  MATSUNAGA TERRY O ,  FRITZ THOMAS A ,  RAMASWAMI VARADA RAJAN

IPC: A61M5/00 ,  A61B8/00 ,  A61K49/00 ,  A61K49/22 ,  A61K51/02 ,  A61B5/055

Abstract: Methods for providing an image of an internal region of a patient. Embodiments of the methods involve administering to the patient a contrast agent which comprises a vesicle composition comprising, in an aqueous carrier, a gas or gaseous precursor and vesicles comprising lipids, proteins or polymers. The patient is scanned using diagnostic imaging, such as ultrasound, to obtain a visible image of the region. The contrast agent is administered to the patient at a rate to substantially eliminate diagnostic artifacts in the image. The methods are particularly useful for diagnosing the presence of any diseased tissue in the patient.

公开(公告)号：EP0930844A4

公开(公告)日：2002-03-13

申请号：EP97928998

申请日：1997-06-16

Applicant: IMARX PHARMACEUTICAL CORP

Inventor： UNGER EVAN C ,  MATSUNAGA TERRY O ,  FRITZ THOMAS A ,  RAMASWAMI VARADA RAJAN

IPC: A61M5/00 ,  A61B8/00 ,  A61K49/00 ,  A61K49/22 ,  A61K51/02 ,  A61B5/055

CPC classification number: A61K49/223 ,  Y10S977/801 ,  Y10S977/927 ,  Y10S977/928 ,  Y10S977/929 ,  Y10S977/93

Abstract: Methods for providing an image of an internal region of a patient. Embodiments of the methods involve administering to the patient a contrast agent which comprises a vesicle composition comprising, in an aqueous carrier, a gas or gaseous precursor and vesicles comprising lipids, proteins or polymers. The patient is scanned using diagnostic imaging, such as ultrasound, to obtain a visible image of the region. The contrast agent is administered to the patient at a rate to substantially eliminate diagnostic artifacts in the image. The methods are particularly useful for diagnosing the presence of any diseased tissue in the patient.