公开(公告)号：WO2016085224A2

公开(公告)日：2016-06-02

申请号：PCT/KR2015/012624

申请日：2015-11-24

Applicant: INSTITUTE FOR BASIC SCIENCE ,  POSTECH ACADEMY-INDUSTRY FOUNDATION

Inventor： LEE, Eunsung ,  KIM, Kimoon ,  PARK, Junbeom ,  SONG, Hayoung ,  KIM, Youngsuk

IPC: C07D233/44 ,  C07D233/91 ,  C07D233/66 ,  A61K31/4168 ,  A61K31/4164

CPC classification number: C07D233/88 ,  C07D233/12

Abstract: The present invention relates to an N-heterocyclic carbene nitric oxide radical, and an application thereof, and more particularly, to an N-heterocyclic carbene nitric oxide radical for effectively delivering nitric oxide having a desirable amount within a short period of time, a method for producing an N-heterocyclic carbene nitric oxide radical, and an application thereof.

Abstract translation: 本发明涉及一种N-杂环卡宾一氧化氮自由基及其应用，更具体地涉及一种用于在短时间内有效输送具有理想量的一氧化氮的N-杂环卡宾一氧化氮基， 用于制备N-杂环卡宾一氧化氮基团及其应用。

公开(公告)号：WO2014077640A1

公开(公告)日：2014-05-22

申请号：PCT/KR2013/010434

申请日：2013-11-15

Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION

Inventor： KIM, Kimoon ,  KO, Young Ho ,  LEE, Su Hyun ,  NARAYANAN, Selvapalam ,  LEE, Don Wook

IPC: A61L9/01 ,  A61L9/04

CPC classification number: A61L9/01

Abstract: Disclosed herein is a composition for slowly releasing a fragrant molecule, including a complex of cucurbituril and a fragrant molecule. The composition is advantageous in that the fragrant molecule is more slowly released when it exists in the form of a complex compared to when it exists alone. Therefore, when a product including this complex is manufactured, the reduction of a fragrant material due to the long-term storage thereof can be minimized, and a fragrant material can be released for a long period of time compared to conventional products. Accordingly, it is presumed that this composition will be applied to air cleaning and environment improvement.

Abstract translation: 本文公开了缓慢释放香料分子的组合物，包括葫芦素和芳香分子的复合物。 组合物的优点在于，当芳族分子以单独存在时与复合物的形式相比较，其缓慢释放。 因此，当制造包括该复合体的产品时，可以将由于长期储存而导致的芳香物质的还原减到最少，并且与传统产品相比可以长时间地释放香料。 因此，推测该组合物将用于空气净化和环境改善。

公开(公告)号：WO2008096985A1

公开(公告)日：2008-08-14

申请号：PCT/KR2008/000625

申请日：2008-02-01

Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION ,  KIM, Kimoon ,  KIM, Hyunuk ,  PARK, Kyeng-Min ,  SAMSONENKO, Denis G. ,  SUN, Yinyong

Inventor： KIM, Kimoon ,  KIM, Hyunuk ,  PARK, Kyeng-Min ,  SAMSONENKO, Denis G. ,  SUN, Yinyong

IPC: C07C7/12 ,  C07C11/24

CPC classification number: B01D53/04 ,  B01D2253/20 ,  B01D2257/104 ,  B01D2257/7022 ,  C01B13/02 ,  C07C7/12 ,  F17C11/005 ,  F17C11/007 ,  C07C11/24

Abstract: Provided are methods of storing and separating acetylene or oxygen using microporous metal formates having a three-dimensional structure of metal and formate ion (HCOO - ). Microporous metal formates used in the method selectively and stably adsorb a large amount of a specific gas within its structure. Therefore, those methods can be used in industrial appliances related to, for example, synthesis and transportation of high-purity gas.

Abstract translation: 提供了使用具有金属和甲酸根离子（HCOO）的三维结构的微孔金属甲酸盐来储存和分离乙炔或氧的方法。 该方法中使用的微孔金属甲酸盐在其结构内选择性且稳定地吸附大量的特定气体。 因此，这些方法可以用于与例如合成和运输高纯度气体有关的工业设备中。

公开(公告)号：WO2005113564A1

公开(公告)日：2005-12-01

申请号：PCT/KR2005/001127

申请日：2005-04-20

Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION ,  KIM, Kimoon ,  OH, Dong-Hyun ,  ERUMAIPATTY RAJAGOUNDER, Nagarajan ,  RAJU, Nandha Kumar ,  CHOI, Ju-Young ,  KO, Young-Ho

Inventor： KIM, Kimoon ,  OH, Dong-Hyun ,  ERUMAIPATTY RAJAGOUNDER, Nagarajan ,  RAJU, Nandha Kumar ,  CHOI, Ju-Young ,  KO, Young-Ho

IPC: C07F7/02

CPC classification number: C07F7/1836 ,  C07B2200/11

Abstract: A disubstituted cucurbituril-bonded silica gel and its use are provided. The disubstituted cu-curbituril-bonded silica gel is useful for removal of air pollutants or water contaminants, and separation and purification of biological, organic, inorganic, or ionic substances.

Abstract translation: 提供二取代的葫芦巴结合硅胶及其用途。 二取代的巧克力百里草键合硅胶可用于去除空气污染物或水污染物，以及生物，有机，无机或离子物质的分离和纯化。

公开(公告)号：WO2014077641A1

公开(公告)日：2014-05-22

申请号：PCT/KR2013/010435

申请日：2013-11-15

Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION

Inventor： KIM, Kimoon ,  KO, Young Ho ,  LEE, Su Hyun ,  NARAYANAN, Selvapalam ,  LEE, Don Wook

IPC: A61L9/01 ,  A61L9/04

CPC classification number: A61L9/014

Abstract: Disclosed herein is a composition for removing an odor molecule and releasing a fragrant molecule, the composition including a complex of cucurbituril and a fragrant molecule. The composition is characterized in that an odor molecule and a fragrant molecule are alternately bonded with cucurbituril, so the odor molecule is bonded with cucurbituril, and, simultaneously, the fragrant molecule is released from the complex. The composition provides very efficient air cleaning effects because it can exhibit both an odor removing effect and a fragrant molecule releasing effect using only cucurbituril which is a single-kind macrocyclic molecule.

Abstract translation: 本文公开了一种用于除去气味分子并释放香味分子的组合物，该组合物包含葫芦素和芳香分子的复合物。 该组合物的特征在于，气味分子和芳香分子与葫芦脲交替结合，因此气味分子与葫芦巴结合，同时，芳香分子从络合物中释放出来。 该组合物提供非常有效的空气净化效果，因为它可以仅使用作为单一大环分子的葫芦素来显示除臭效果和芳香分子释放作用。

公开(公告)号：WO2007046575A1

公开(公告)日：2007-04-26

申请号：PCT/KR2006/000687

申请日：2006-02-28

Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION

Inventor： KIM, Kimoon ,  BAEK, Kangkyun ,  KIM, Jeeyoun ,  HWANG, Ilha ,  KO, Young-Ho ,  SELVAPALAM, Narayanan ,  NAGARAJAN, Erumaipatty R. ,  PARK, Kyeng-Min

IPC: C07D487/04

CPC classification number: C07D487/22 ,  B01D15/3804 ,  B01J31/0249 ,  B01J31/0251 ,  B01J31/1658 ,  B82Y5/00 ,  B82Y15/00 ,  C07K1/22

Abstract: Provided are a kit including a first component that is a compound of formula (1) below bound to a first material and a second component that is a ligand bound to a second material, wherein each of the first and second materials is independently selected from the group consisting of a solid phase, a biomolecule, an antioxidant, a chemical therapeutic agent, an anti-histaminic agent, a cucurbituril dendrimer, a cyclodextrin derivative, a crown ether derivative, a calixarene derivative, a cyclophane derivative, a cyclic peptide derivative, a metallic ion, a chromophore, a fluorescent material, a phosphor, a radioactive material, and a catalyst; and the ligand can non-covalently bind to the compound of formula (1); a method of separating and purifying a material bound to a ligand using the compound of formula (1) bound to a solid phase; a method of separating and purifying the compound of formula (1) or a material bound to the compound using a ligand bound to a solid phase; a sensor chip including a compound of formula (1) bound to a first material and a ligand bound to a second material; and a solid-catalyst complex including the compound of formula (1) bound to a first material and a ligand bound to a second material.

Abstract translation: 本发明提供了一种试剂盒，其包括第一组分，其为下式结合于第一材料的式（1）化合物，第二组分为与第二材料结合的配体，其中第一和第二材料中的每一种独立地选自 由固相，生物分子，抗氧化剂，化学治疗剂，抗组胺药，葫芦巴树枝状大分子，环糊精衍生物，冠醚衍生物，杯芳烃衍生物，环戊烷衍生物，环肽衍生物， 金属离子，发色团，荧光材料，荧光体，放射性材料和催化剂; 并且配体可以非共价结合式（1）的化合物; 使用与固相结合的式（1）化合物分离和纯化与配体结合的材料的方法; 使用与固相结合的配体分离和纯化式（1）化合物或与化合物结合的物质的方法; 包含与第一材料结合的式（1）化合物和与第二材料结合的配体的传感器芯片; 和包含与第一材料结合的式（1）化合物和与第二材料结合的配体的固体催化剂络合物。

公开(公告)号：WO2014077642A1

公开(公告)日：2014-05-22

申请号：PCT/KR2013/010436

申请日：2013-11-15

Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION

Inventor： KIM, Kimoon ,  KO, Young Ho ,  LEE, Su Hyun ,  NARAYANAN, Selvapalam ,  LEE, Don Wook

IPC: A61L9/01 ,  A61L9/04

CPC classification number: A61L9/014

Abstract: Disclosed herein is a composition for removing odor, the composition including cucurbituril. The composition can capture and remove various kinds of odor materials (particularly, ammonium ion-containing bad odor, such as a fishy smell or the like) because cucurbituril can interact with various odor materials using its hydrophobic cavity and both inlets covered with carbonyl groups. Therefore, this composition can be practically applied to the cleaning of air and the improvement of an environment.

Abstract translation: 本文公开了用于除去气味的组合物，该组合物包括葫芦素。 由于葫芦巴可以使用其疏水腔和两个入口被羰基覆盖，因此可以捕获并除去各种气味物质（特别是含有铵离子的不良气味，例如鱼腥味等）。 因此，该组合物可以实际应用于清洁空气和改善环境。

公开(公告)号：WO2009128649A3

公开(公告)日：2009-10-22

申请号：PCT/KR2009/001947

申请日：2009-04-15

Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION ,  LEE, Don-Wook ,  RYU, Sung Ho ,  HA, Sang Hoon ,  JUNG, Hyuntae ,  MAINAK, Banerjee ,  SELVAPALAM, Narayanan ,  KIM, Kimoon ,  PARK, Kyeng-Min

Inventor： LEE, Don-Wook ,  RYU, Sung Ho ,  HA, Sang Hoon ,  JUNG, Hyuntae ,  MAINAK, Banerjee ,  SELVAPALAM, Narayanan ,  KIM, Kimoon ,  PARK, Kyeng-Min

IPC: C12N15/10

Abstract: Provided is a method of separating cellular components, the method including: a) contacting a guest compound-bound reactive compound with cells; b) lysing the cells; c) adding a host compound-bound solid phase to a solution including the lysates of the cells to prepare a mixture; d) separating binding pairs of the guest compound bound to cellular components and the host compound bound to the solid phase from the mixture, and purifying the binding pairs; and e) separating the cellular components from the binding pairs, wherein the guest compound-bound reactive compound is obtained through a covalent bond between a reactive compound and a guest compound represented by Formula 2 below guest, the host compound-bound solid phase is obtained through a covalent bond between a solid phase and a host compound represented by Formula 1 below, and the reactive compound includes at least one selected from the group consisting of a biomolecule, N-hydroxysuccimide, an antigen, an antibody, an aptamer, folic acid, transferrin, and any mixtures thereof.

公开(公告)号：WO2007111390A1

公开(公告)日：2007-10-04

申请号：PCT/KR2006/001096

申请日：2006-03-24

Applicant: POSTECH FOUNDATION ,  POSTECH ACADEMY-INDUSTRY FOUNDATION ,  KIM, Kimoon ,  KO, Young-Ho ,  PARK, Kyeng-Min ,  SELVAPALAM, Narayanan ,  NAGARAJAN, Erumaipatty, R.

Inventor： KIM, Kimoon ,  KO, Young-Ho ,  PARK, Kyeng-Min ,  SELVAPALAM, Narayanan ,  NAGARAJAN, Erumaipatty, R.

IPC: C07D305/14 ,  C07D487/04

CPC classification number: C07D487/04 ,  B01J20/286 ,  C07D305/14

Abstract: Provided are a stationary phase and a column using a cucurbituril-bound silica g el, and a method of separating taxane using the column. The taxane separation meth od includes: preparing a column for taxane separation, the column being packed with a stationary phase including a cucurbituril-bound silica gel in which a cucurbituril represen ted by Formula 1 or 2 is covalently bound to a modified silica gel represented by Formul a 3; dissolving a taxane powder in a solvent to prepare a taxane-containing solution; ap plying the taxane-containing solution to the column; supplying a mobile-phase solvent t o the column to obtain a taxane extract from the column; and purifying taxane from the t axane extract. Therefore, highly purified taxane can be separated from a low-purity cr ude taxane extract.

Abstract translation: 提供了使用葫芦巴结合二氧化硅的固定相和柱，以及使用该柱分离紫杉烷的方法。 紫杉烷分离方法包括：制备紫杉烷分离柱，柱用包含葫芦素结合硅胶的固定相填充，其中由式1或2表示的葫芦巴共价结合到由 Formul a 3; 将紫杉烷粉末溶解在溶剂中以制备含紫杉烷的溶液; 将含有紫杉烷的溶液置于色谱柱上; 在柱上供应流动相溶剂以从塔中获得紫杉烷提取物; 并从t轴提取物中纯化紫杉烷。 因此，高纯度紫杉烷可与低纯度紫杉烷提取物分离。

公开(公告)号：WO2007102634A1

公开(公告)日：2007-09-13

申请号：PCT/KR2006/000841

申请日：2006-03-09

Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION ,  KIM, Kimoon ,  PARK, Kyeng-Min ,  KO, Young-Ho ,  SELVAPALAM, Narayanan

Inventor： KIM, Kimoon ,  PARK, Kyeng-Min ,  KO, Young-Ho ,  SELVAPALAM, Narayanan

IPC: A24D3/04

CPC classification number: A24D1/002 ,  A24D3/14

Abstract: Provided is a cucurbituril-containing tobacco. The cucurbituril-containing tobacco includes a cucurbituril represented by Formula 1. The cucurbituril-containing tobacco can produce a reduced amount of harmful substances.

Abstract translation: 提供含有葫芦素的烟草。 含葫芦素的烟草包括由式1表示的葫芦巴脲。含葫芦素的烟草可以产生减少量的有害物质。