HAIR GROWTH REGULATING AGENT
    1.
    发明申请
    HAIR GROWTH REGULATING AGENT 审中-公开
    头发生长调节剂

    公开(公告)号:WO2010016606A3

    公开(公告)日:2010-04-15

    申请号:PCT/JP2009064099

    申请日:2009-08-04

    CPC classification number: A61K8/41 A61K8/42 A61K8/44 A61Q7/02 Y02P20/582

    Abstract: A hair growth regulating agent containing, as an active ingredient, a compound represented by the following formula (I): [wherein R1 represents a substituted or unsubstituted, linear or branched C2 to C25 alkyl group; a group represented by the following formula (II): (wherein R1' represents a substituted or unsubstituted, linear or branched C2 to C20 alkylene group, or -(CH2)n-{O-(CH2)m}o-O-(CH2)p- in which each of n, m, o, and p is an integer from 1 to 6; X' represents -CO-NH-, -O-CO-O-, -NH-CO-, -CO-O-, -O-CO-, or -O-; Y' represents a substituted or unsubstituted C1 to C4 alkylene group; R2' represents a hydrogen atom or a C1 to C4 alkyl group; R3' represents a C1 to C4 alkyl group; and when R2' and R3' each represent a C1 to C4 alkyl group, the two alkyl groups may be identical to or different from each other); or a group represented by the following formula (III): (wherein R1', X', and Y' have the same meanings as defined above; R4', R5', and R6', which may be identical to or different from one another, each represent a C1 to C4 alkyl group; and A'- represents a counter ion); X represents -CO-NH-, -O-CO-O-, -NH-CO-, -CO-O-, -O-CO-, or -O-; Y represents a substituted or unsubstituted C1 to C4 alkylene group; R2 represents a hydrogen atom or a C1 to C4 alkyl group; R3 represents a C1 to C4 alkyl group; and when R2 and R3 each represent a C1 to C4 alkyl group, the two alkyl groups may be identical to or different from each other] or a salt of the compound; and/or a quaternary ammonium salt represented by the following formula (IV): (wherein R1, X, and Y have the same meanings as defined above; R4, R5, and R6, which may be identical to or different from one another, each represent a C1 to C4 alkyl group; and A- represents a counter ion).

    Abstract translation: 一种毛发生长调节剂,其含有下式(I)表示的化合物作为活性成分:[其中R1表示取代或未取代的,直链或支链的C2至C25烷基; (II)表示的基团,式中,R 1'表示取代或未取代的直链或支链的碳原子数2〜20的亚烷基或 - (CH 2)n - {O-(CH 2)m} o -O-(CH 2) 其中n,m,o和p各自为1至6的整数; X'表示-CO-NH-,-O-CO-O-,-NH-CO-,-CO-O- ,-O-CO-或-O-; Y'表示取代或未取代的C1至C4亚烷基; R2'表示氢原子或C1至C4烷基; R3'表示C1至C4烷基;和 当R2'和R3'各自表示C1至C4烷基时,这两个烷基可以彼此相同或不同); 或由下式(III)表示的基团:其中R1',X'和Y'具有与上述定义相同的含义; R4',R5'和R6'可以相同或不同于 另一个表示C1至C4烷基;并且A'-表示抗衡离子)。 X表示-CO-NH - , - O-CO-O-,-NH-CO-,-CO-O - , - O-CO-或-O-; Y表示取代或未取代的C1至C4亚烷基; R2代表氢原子或C1至C4烷基; R3代表C1至C4烷基; 并且当R2和R3各自表示C1-C4烷基时,这两个烷基可以彼此相同或不同]或该化合物的盐; 和/或由下式(IV)表示的季铵盐:(其中R1,X和Y具有与上述定义相同的含义; R4,R5和R6可以彼此相同或不同, 各自表示C1至C4烷基;并且A-表示抗衡离子)。

    Hair growing or hair fostering agent
    4.
    发明专利
    Hair growing or hair fostering agent 有权
    头发生长或毛发滋养剂

    公开(公告)号:JP2010200767A

    公开(公告)日:2010-09-16

    申请号:JP2010129792

    申请日:2010-06-07

    Abstract: PROBLEM TO BE SOLVED: To provide a hair fostering agent promoting hair growing and hair fostering and effective for various alopecia, regardless of disease condition and constitution.
    SOLUTION: There is provided a microorganism deposited with National Institute of Advanced Industrial Science and Technology Patent Microorganisms Depositary as FERM P-20586.
    COPYRIGHT: (C)2010,JPO&INPIT

    Abstract translation: 要解决的问题:提供促进头发生长和发育的发育剂,并且对于各种脱发有效,不论疾病状况和结构如何。

    解决方案:提供了一种保藏在FERM P-20586的国家先进工业科技专利微生物保藏研究所的微生物。 版权所有(C)2010,JPO&INPIT

    Hair growth inhibitor
    5.
    发明专利
    Hair growth inhibitor 有权
    头发生长抑制剂

    公开(公告)号:JP2010037274A

    公开(公告)日:2010-02-18

    申请号:JP2008202234

    申请日:2008-08-05

    CPC classification number: A61K8/41 A61K8/42 A61K8/44 A61Q7/02 Y02P20/582

    Abstract: PROBLEM TO BE SOLVED: To provide a hair growth inhibitor having sufficient hair growth inhibitory activity.
    SOLUTION: The hair growth inhibitor comprises, as an active ingredient, a compound of formula (I): R
    1 -X-Y-NR
    2 R
    3 [wherein, R
    1 is a (substituted) linear or branched-chain 2-25C alkyl]. Specific examples of the inhibitor include 2-dimethylamino-N-ethyl-acetamide, dodecylcarbamoylmethyl trimethylammonium chloride, 2-dimethylamino-N-(2-{2-[2-(2-dimethylamino-acetylamino)-ethoxy]-ethoxy}-ethyl)-acetamide, 2-dimethylamino-N-[8-(2-dimethylamino-acetylamino)-octyl]-acetamide and 2-dimethylamino-N-[2-(2-{2-[2-(2-dimethylamino-acetylamino)-ethoxy]-ethoxy}-ethoxy)-ethyl]-acetamide.
    COPYRIGHT: (C)2010,JPO&INPIT

    Abstract translation: 要解决的问题:提供具有足够的毛发生长抑制活性的毛发生长抑制剂。 解决方案:毛发生长抑制剂包含作为活性成分的式(I)化合物:R SB 1 -XY-NR SB 2 R SB [其中,R SB 1是(取代的)直链或支链2-25C烷基]。 抑制剂的具体实例包括2-二甲基氨基-N-乙基 - 乙酰胺,十二烷基氨基甲酰基甲基三甲基氯化铵,2-二甲基氨基-N-(2- [2- [2-(2-二甲基氨基 - 乙酰氨基) - 乙氧基] - 乙氧基} - 乙基) - 乙酰胺,2-二甲基氨基-N- [8-(2-二甲基氨基 - 乙酰氨基) - 辛基] - 乙酰胺和2-二甲基氨基-N- [2-(2- [2- [2-(2-二甲基氨基 - 乙酰氨基) - 乙氧基]乙氧基} - 乙氧基) - 乙基] - 乙酰胺。 版权所有(C)2010,JPO&INPIT

    Hair growth-inhibiting agent and unhairing agent
    7.
    发明专利
    Hair growth-inhibiting agent and unhairing agent 审中-公开
    头发生长抑制剂和吸收剂

    公开(公告)号:JP2010275203A

    公开(公告)日:2010-12-09

    申请号:JP2009127009

    申请日:2009-05-26

    Abstract: PROBLEM TO BE SOLVED: To provide a hair growth-inhibiting agent having high hair growth-inhibiting effects, and to provide an unhairing agent having high unhairing-promoting effects.
    SOLUTION: The hair growth-inhibiting agent and the unhairing agent contain a compound represented by general formula (I) as an active ingredient. In the formula, Q is a single bond or alkylene; X is -NH- or -C-; and R
    11 is hydrogen or an alkyl.
    COPYRIGHT: (C)2011,JPO&INPIT

    Abstract translation: 待解决的问题:提供具有高毛发生长抑制作用的毛发生长抑制剂,并提供具有高脱毛促进作用的脱毛剂。 毛发生长抑制剂和脱毛剂含有通式(I)表示的化合物作为有效成分。 在该式中,Q是单键或亚烷基; X是-NH-或-C-; R 11是氢或烷基。 版权所有(C)2011,JPO&INPIT

    Hair growth promoter
    8.
    发明专利
    Hair growth promoter 有权
    头发生长促进剂

    公开(公告)号:JP2008001656A

    公开(公告)日:2008-01-10

    申请号:JP2006174025

    申请日:2006-06-23

    Abstract: PROBLEM TO BE SOLVED: To provide a hair growth promoter containing a culture extract of a microorganism belonging to the genus Bacillus and having hair growing activity.
    SOLUTION: The hair growth promoter contains a culture extract of a microorganism belonging to the genus Bacillus as an active component. Particularly, the microorganism belonging to the genus Bacillus is a strain specified by the accession number FERM P-20835 or Bacillus subtilis IFO 13719.
    COPYRIGHT: (C)2008,JPO&INPIT

    Abstract translation: 待解决的问题:提供一种包含属于芽孢杆菌属的微生物的培养提取物并具有发育生长活性的毛发生长促进剂。 毛发生长促进剂含有作为活性成分的属于芽孢杆菌属的微生物的培养提取物。 特别地,属于芽孢杆菌属的微生物是由登录号FERM P-20835或枯草芽孢杆菌IFO 13719指定的菌株。版权所有(C)2008,JPO&INPIT

    Hair growth tonic
    9.
    发明专利
    Hair growth tonic 有权
    头发生长剂

    公开(公告)号:JP2006306737A

    公开(公告)日:2006-11-09

    申请号:JP2005127969

    申请日:2005-04-26

    Abstract: PROBLEM TO BE SOLVED: To provide a hair growth tonic high in safety and superior in hair regenerating effect. SOLUTION: The hair growth tonic contains Saxifraga stolonifera or its extract as an effective component. By applying the hair growth tonic of the invention to the scalp or the like, superior trichogenous, pilatory, and hair growing actions are exhibited at the applied portion. COPYRIGHT: (C)2007,JPO&INPIT

    Abstract translation: 要解决的问题:提供高安全性的头发生长滋补剂和优异的毛发再生效果。

    解决方案:头发生长补品含有Saxifraga stolonifera或其提取物作为有效成分。 通过将本发明的毛发生长补品应用于头皮等,在施用部分显示出优异的毛发,拔毛和生长的作用。 版权所有(C)2007,JPO&INPIT

    TRICHOGENOUS SUPPRESSANT
    10.
    发明专利

    公开(公告)号:JPH1160451A

    公开(公告)日:1999-03-02

    申请号:JP22935197

    申请日:1997-08-26

    Applicant: KAO CORP

    Abstract: PROBLEM TO BE SOLVED: To obtain the subject suppressant capable of effectively suppressing the growth of body hair and reducing the frequency of treating body hair removal by including an Aloe ferox or the like and/or Lithospermum erythrorhizon or the like or an extract thereof as an active ingredient therein. SOLUTION: This trichogenous suppressant is obtained by including directly Aloe ferox or the like and/or Lithospermum erythrorhizon or the like, preferably any one site or more of the whole herb, a leaf, a stem, a root, a fruit, a seed and a flower or an extract therefrom as an active ingredient. The suppressant is preferably formulated with a hair removing agent, e.g. a pasty, a creamy or an aerosol-like agent, a depilatory agent, e.g. a waxy, a jelly or a sheetlike agent or a shaving agent, e.g. a shaving cream. The amount of the formulated active ingredient is preferably 0.001-10 wt.% expressed in terms of a dry solid content. An optional ingredient such as purified water, ethanol, an oily ingredient, a humectant, a thickener, a preservative, an emulsifying agent, a pharmacodynamically effective ingredient, a powder or an ultraviolet light absorber can be formulated with the suppressant.

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