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公开(公告)号:WO2010016606A3
公开(公告)日:2010-04-15
申请号:PCT/JP2009064099
申请日:2009-08-04
Applicant: KAO CORP , SUZUKI YASUTO , MORISAKI NAOKO , SASAJIMA MICHIYO
Inventor: SUZUKI YASUTO , MORISAKI NAOKO , SASAJIMA MICHIYO
CPC classification number: A61K8/41 , A61K8/42 , A61K8/44 , A61Q7/02 , Y02P20/582
Abstract: A hair growth regulating agent containing, as an active ingredient, a compound represented by the following formula (I): [wherein R1 represents a substituted or unsubstituted, linear or branched C2 to C25 alkyl group; a group represented by the following formula (II): (wherein R1' represents a substituted or unsubstituted, linear or branched C2 to C20 alkylene group, or -(CH2)n-{O-(CH2)m}o-O-(CH2)p- in which each of n, m, o, and p is an integer from 1 to 6; X' represents -CO-NH-, -O-CO-O-, -NH-CO-, -CO-O-, -O-CO-, or -O-; Y' represents a substituted or unsubstituted C1 to C4 alkylene group; R2' represents a hydrogen atom or a C1 to C4 alkyl group; R3' represents a C1 to C4 alkyl group; and when R2' and R3' each represent a C1 to C4 alkyl group, the two alkyl groups may be identical to or different from each other); or a group represented by the following formula (III): (wherein R1', X', and Y' have the same meanings as defined above; R4', R5', and R6', which may be identical to or different from one another, each represent a C1 to C4 alkyl group; and A'- represents a counter ion); X represents -CO-NH-, -O-CO-O-, -NH-CO-, -CO-O-, -O-CO-, or -O-; Y represents a substituted or unsubstituted C1 to C4 alkylene group; R2 represents a hydrogen atom or a C1 to C4 alkyl group; R3 represents a C1 to C4 alkyl group; and when R2 and R3 each represent a C1 to C4 alkyl group, the two alkyl groups may be identical to or different from each other] or a salt of the compound; and/or a quaternary ammonium salt represented by the following formula (IV): (wherein R1, X, and Y have the same meanings as defined above; R4, R5, and R6, which may be identical to or different from one another, each represent a C1 to C4 alkyl group; and A- represents a counter ion).
Abstract translation: 一种毛发生长调节剂,其含有下式(I)表示的化合物作为活性成分:[其中R1表示取代或未取代的,直链或支链的C2至C25烷基; (II)表示的基团,式中,R 1'表示取代或未取代的直链或支链的碳原子数2〜20的亚烷基或 - (CH 2)n - {O-(CH 2)m} o -O-(CH 2) 其中n,m,o和p各自为1至6的整数; X'表示-CO-NH-,-O-CO-O-,-NH-CO-,-CO-O- ,-O-CO-或-O-; Y'表示取代或未取代的C1至C4亚烷基; R2'表示氢原子或C1至C4烷基; R3'表示C1至C4烷基;和 当R2'和R3'各自表示C1至C4烷基时,这两个烷基可以彼此相同或不同); 或由下式(III)表示的基团:其中R1',X'和Y'具有与上述定义相同的含义; R4',R5'和R6'可以相同或不同于 另一个表示C1至C4烷基;并且A'-表示抗衡离子)。 X表示-CO-NH - , - O-CO-O-,-NH-CO-,-CO-O - , - O-CO-或-O-; Y表示取代或未取代的C1至C4亚烷基; R2代表氢原子或C1至C4烷基; R3代表C1至C4烷基; 并且当R2和R3各自表示C1-C4烷基时,这两个烷基可以彼此相同或不同]或该化合物的盐; 和/或由下式(IV)表示的季铵盐:(其中R1,X和Y具有与上述定义相同的含义; R4,R5和R6可以彼此相同或不同, 各自表示C1至C4烷基;并且A-表示抗衡离子)。
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公开(公告)号:DE602008002079D1
公开(公告)日:2010-09-23
申请号:DE602008002079
申请日:2008-02-20
Applicant: KAO CORP
Inventor: SASAJIMA MICHIYO , ITO NORIKO , MORIWAKI SHIGERU , FUSE CHIE
IPC: G01N33/50
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公开(公告)号:EP2444097A4
公开(公告)日:2012-11-14
申请号:EP09846118
申请日:2009-06-15
Applicant: KAO CORP
Inventor: NAGASAWA AZUMI , MORIWAKI SHIGERU , SASAKI MITSUYOSHI , MATSUOKA MEGUMI , SASAJIMA MICHIYO , ITO NORIKO
IPC: A61K36/23 , A61K8/97 , A61P1/04 , A61P1/16 , A61P1/18 , A61P3/10 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/12 , A61P15/00 , A61P17/00 , A61P17/06 , A61P17/14 , A61P19/00 , A61P21/00 , A61P25/00 , A61P29/00 , A61P31/00 , A61P31/04
CPC classification number: A61K36/232 , A61K8/97 , A61Q7/00 , A61Q19/00
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公开(公告)号:JP2010200767A
公开(公告)日:2010-09-16
申请号:JP2010129792
申请日:2010-06-07
Inventor: TAKIGAWA HIROBUMI , SASAJIMA MICHIYO , ITO NORIKO
Abstract: PROBLEM TO BE SOLVED: To provide a hair fostering agent promoting hair growing and hair fostering and effective for various alopecia, regardless of disease condition and constitution.
SOLUTION: There is provided a microorganism deposited with National Institute of Advanced Industrial Science and Technology Patent Microorganisms Depositary as FERM P-20586.
COPYRIGHT: (C)2010,JPO&INPITAbstract translation: 要解决的问题:提供促进头发生长和发育的发育剂,并且对于各种脱发有效,不论疾病状况和结构如何。
解决方案:提供了一种保藏在FERM P-20586的国家先进工业科技专利微生物保藏研究所的微生物。 版权所有(C)2010,JPO&INPIT
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公开(公告)号:JP2010037274A
公开(公告)日:2010-02-18
申请号:JP2008202234
申请日:2008-08-05
Inventor: SUZUKI YASUTO , MORIZAKI NAOKO , SASAJIMA MICHIYO
CPC classification number: A61K8/41 , A61K8/42 , A61K8/44 , A61Q7/02 , Y02P20/582
Abstract: PROBLEM TO BE SOLVED: To provide a hair growth inhibitor having sufficient hair growth inhibitory activity.
SOLUTION: The hair growth inhibitor comprises, as an active ingredient, a compound of formula (I): R
1 -X-Y-NR
2 R
3 [wherein, R
1 is a (substituted) linear or branched-chain 2-25C alkyl]. Specific examples of the inhibitor include 2-dimethylamino-N-ethyl-acetamide, dodecylcarbamoylmethyl trimethylammonium chloride, 2-dimethylamino-N-(2-{2-[2-(2-dimethylamino-acetylamino)-ethoxy]-ethoxy}-ethyl)-acetamide, 2-dimethylamino-N-[8-(2-dimethylamino-acetylamino)-octyl]-acetamide and 2-dimethylamino-N-[2-(2-{2-[2-(2-dimethylamino-acetylamino)-ethoxy]-ethoxy}-ethoxy)-ethyl]-acetamide.
COPYRIGHT: (C)2010,JPO&INPITAbstract translation: 要解决的问题:提供具有足够的毛发生长抑制活性的毛发生长抑制剂。 解决方案:毛发生长抑制剂包含作为活性成分的式(I)化合物:R SB 1 -XY-NR SB 2 R SB SB> [其中,R SB 1是(取代的)直链或支链2-25C烷基]。 抑制剂的具体实例包括2-二甲基氨基-N-乙基 - 乙酰胺,十二烷基氨基甲酰基甲基三甲基氯化铵,2-二甲基氨基-N-(2- [2- [2-(2-二甲基氨基 - 乙酰氨基) - 乙氧基] - 乙氧基} - 乙基) - 乙酰胺,2-二甲基氨基-N- [8-(2-二甲基氨基 - 乙酰氨基) - 辛基] - 乙酰胺和2-二甲基氨基-N- [2-(2- [2- [2-(2-二甲基氨基 - 乙酰氨基) - 乙氧基]乙氧基} - 乙氧基) - 乙基] - 乙酰胺。 版权所有(C)2010,JPO&INPIT
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公开(公告)号:JP2013091622A
公开(公告)日:2013-05-16
申请号:JP2011235172
申请日:2011-10-26
Inventor: ITO NORIKO , SASAJIMA MICHIYO , WATANABE MANABU
Abstract: PROBLEM TO BE SOLVED: To provide a substance for inhibiting growth of hair.SOLUTION: The hair growth inhibitor has Acer spicatum or an extract thereof as an active ingredient.
Abstract translation: 待解决的问题:提供抑制头发生长的物质。 毛发生长抑制剂具有Acer spicatum或其提取物作为活性成分。 版权所有(C)2013,JPO&INPIT
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公开(公告)号:JP2010275203A
公开(公告)日:2010-12-09
申请号:JP2009127009
申请日:2009-05-26
Inventor: WATANABE MANABU , SUZUKI YASUTO , SASAJIMA MICHIYO , MORIZAKI NAOKO
IPC: A61K8/49 , A61K31/4015 , A61K31/4166 , A61P17/14 , A61Q7/02
Abstract: PROBLEM TO BE SOLVED: To provide a hair growth-inhibiting agent having high hair growth-inhibiting effects, and to provide an unhairing agent having high unhairing-promoting effects.
SOLUTION: The hair growth-inhibiting agent and the unhairing agent contain a compound represented by general formula (I) as an active ingredient. In the formula, Q is a single bond or alkylene; X is -NH- or -C-; and R
11 is hydrogen or an alkyl.
COPYRIGHT: (C)2011,JPO&INPITAbstract translation: 待解决的问题:提供具有高毛发生长抑制作用的毛发生长抑制剂,并提供具有高脱毛促进作用的脱毛剂。 毛发生长抑制剂和脱毛剂含有通式(I)表示的化合物作为有效成分。 在该式中,Q是单键或亚烷基; X是-NH-或-C-; R 11是氢或烷基。 版权所有(C)2011,JPO&INPIT
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公开(公告)号:JP2008001656A
公开(公告)日:2008-01-10
申请号:JP2006174025
申请日:2006-06-23
Inventor: TAKIGAWA HIROBUMI , SASAJIMA MICHIYO , ITO NORIKO
Abstract: PROBLEM TO BE SOLVED: To provide a hair growth promoter containing a culture extract of a microorganism belonging to the genus Bacillus and having hair growing activity.
SOLUTION: The hair growth promoter contains a culture extract of a microorganism belonging to the genus Bacillus as an active component. Particularly, the microorganism belonging to the genus Bacillus is a strain specified by the accession number FERM P-20835 or Bacillus subtilis IFO 13719.
COPYRIGHT: (C)2008,JPO&INPITAbstract translation: 待解决的问题:提供一种包含属于芽孢杆菌属的微生物的培养提取物并具有发育生长活性的毛发生长促进剂。 毛发生长促进剂含有作为活性成分的属于芽孢杆菌属的微生物的培养提取物。 特别地,属于芽孢杆菌属的微生物是由登录号FERM P-20835或枯草芽孢杆菌IFO 13719指定的菌株。版权所有(C)2008,JPO&INPIT
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公开(公告)号:JP2006306737A
公开(公告)日:2006-11-09
申请号:JP2005127969
申请日:2005-04-26
Inventor: SASAJIMA MICHIYO , ITO NORIKO , KUSUOKU HIROSHI
Abstract: PROBLEM TO BE SOLVED: To provide a hair growth tonic high in safety and superior in hair regenerating effect. SOLUTION: The hair growth tonic contains Saxifraga stolonifera or its extract as an effective component. By applying the hair growth tonic of the invention to the scalp or the like, superior trichogenous, pilatory, and hair growing actions are exhibited at the applied portion. COPYRIGHT: (C)2007,JPO&INPIT
Abstract translation: 要解决的问题:提供高安全性的头发生长滋补剂和优异的毛发再生效果。
解决方案:头发生长补品含有Saxifraga stolonifera或其提取物作为有效成分。 通过将本发明的毛发生长补品应用于头皮等,在施用部分显示出优异的毛发,拔毛和生长的作用。 版权所有(C)2007,JPO&INPIT
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公开(公告)号:JPH1160451A
公开(公告)日:1999-03-02
申请号:JP22935197
申请日:1997-08-26
Applicant: KAO CORP
Inventor: SASAJIMA MICHIYO , NISHIJIMA AYUMI , HOTTA MITSUYUKI , KANAZAWA SATOSHI , NISHIZAWA YOSHINORI
IPC: A61K8/00 , A61K8/97 , A61K36/00 , A61K36/18 , A61K36/896 , A61P17/00 , A61P43/00 , A61Q5/00 , A61Q9/04 , A61K7/06
Abstract: PROBLEM TO BE SOLVED: To obtain the subject suppressant capable of effectively suppressing the growth of body hair and reducing the frequency of treating body hair removal by including an Aloe ferox or the like and/or Lithospermum erythrorhizon or the like or an extract thereof as an active ingredient therein. SOLUTION: This trichogenous suppressant is obtained by including directly Aloe ferox or the like and/or Lithospermum erythrorhizon or the like, preferably any one site or more of the whole herb, a leaf, a stem, a root, a fruit, a seed and a flower or an extract therefrom as an active ingredient. The suppressant is preferably formulated with a hair removing agent, e.g. a pasty, a creamy or an aerosol-like agent, a depilatory agent, e.g. a waxy, a jelly or a sheetlike agent or a shaving agent, e.g. a shaving cream. The amount of the formulated active ingredient is preferably 0.001-10 wt.% expressed in terms of a dry solid content. An optional ingredient such as purified water, ethanol, an oily ingredient, a humectant, a thickener, a preservative, an emulsifying agent, a pharmacodynamically effective ingredient, a powder or an ultraviolet light absorber can be formulated with the suppressant.
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