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Patent Agency Ranking1.发明申请HESPERIDIN AND HESPERETIN AS 3-HYDROXY-3-METHYLGLUTARYL CoA(HMG-CoA) REDUCTASE INHIBITOR 审中-公开作为3-羟基-3-甲基胆碱CoA（HMG-CoA）还原酶抑制剂的HESPERIDIN和HESPERETIN
公开(公告)号：WO1998016220A1
公开(公告)日：1998-04-23
申请号：PCT/KR1997000190
申请日：1997-10-13
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , BOK, Song, Hae , SON, Kwang, Hee , JEONG, Tae, Sook , KWON, Byoung, Mog , KIM, Young, Kook , CHOI, Doil , KIM, Sung, Uk , BAE, Ki, Hwan , PARK, Yong, Bok , CHOI, Myung, Sook , HWANG, Ingyu , MOON, Surk, Sik , KWON, Yong, Kook , AHN, Jung, Ah , LEE, Eun, Sook
IPC: A61K31/35
CPC classification number: A61K31/7048 , A23L2/52 , A23L33/105 , A61K31/352
Abstract: A pharmaceutical composition for inhibiting the activity of 3-hydroxy-3-methylglutaryl CoA(HMG-CoA) reductase in mammals comprises an effective amount of hesperidin or hesperetin as an active ingredient together with a pharmaceutically acceptable carrier, and a food or beverage composition for inhibiting the 3-hydroxy-3-methylglutaryl CoA(HMG-CoA) reductase activity in mammals comprises an effective amount of hesperidin or hesperetin.
Abstract translation: 用于抑制哺乳动物中3-羟基-3-甲基戊二酰CoA（HMG-CoA）还原酶的活性的药物组合物包含有效量的橙皮苷或橙皮素作为活性成分以及药学上可接受的载体，以及用于 抑制哺乳动物中的3-羟基-3-甲基戊二酰辅酶A（HMG-CoA）还原酶活性包括有效量的橙皮苷或橙皮素。
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2.发明申请CITRUS PEEL EXTRACT AS 3-HYDROXY-3-METHYLGLUTARYL CoA(HMG-CoA) REDUCTASE INHIBITOR 审中-公开CITRUS PEEL提取物作为3-羟基-3-甲基胆碱CoA（HMG-CoA）还原酶抑制剂
公开(公告)号：WO1998016239A1
公开(公告)日：1998-04-23
申请号：PCT/KR1997000192
申请日：1997-10-13
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , BOK, Song, Hae , SON, Kwang, Hee , JEONG, Tae, Sook , KWON, Byoung, Mog , KIM, Young, Kook , CHOI, Doil , KIM, Sung, Uk , BAE, Ki, Hwan , PARK, Yong, Bok , CHOI, Myung, Sook , HWANG, Ingyu , MOON, Surk, Sik , KWON, Yong, Kook , AHN, Jung, Ah , LEE, Eun, Sook
IPC: A61K35/78
CPC classification number: A61K31/7048 , A23L2/52 , A23L33/105 , A61K31/352
Abstract: A pharmaceutical composition for inhibiting the activity of 3-hydroxy-3-methylglutaryl CoA(HMG-CoA) reductase in mammals comprises an effective amount of citrus peel extract as an active ingredient together with a pharmaceutically acceptable carrier, and a food or beverage composition for inhibiting the 3-hydroxy-3-methylglutaryl CoA(HMG-CoA) reductase activity comprises an effective amount of citrus peel extract.
Abstract translation: 用于抑制哺乳动物中3-羟基-3-甲基戊二酰CoA（HMG-CoA）还原酶的活性的药物组合物包括有效量的柑橘皮提取物作为活性成分以及药学上可接受的载体，以及用于 抑制3-羟基-3-甲基戊二酰辅酶A（HMG-CoA）还原酶活性包括有效量的柑橘皮提取物。
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3.发明申请NARINGIN AND NARINGENIN AS 3-HYDROXY-3-METHYLGLUTARYL CoA(HMG-CoA) REDUCTASE INHIBITOR 审中-公开NARINGIN和NARINGENIN作为3-羟基-3-甲基胆碱CoA（HMG-CoA）还原酶抑制剂
公开(公告)号：WO1998016221A1
公开(公告)日：1998-04-23
申请号：PCT/KR1997000191
申请日：1997-10-13
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , BOK, Song, Hae , SON, Kwang, Hee , JEONG, Tae, Sook , KWON, Byoung, Mog , KIM, Young, Kook , CHOI, Doil , KIM, Sung, Uk , BAE, Ki, Hwan , PARK, Yong, Bok , CHOI, Myung, Sook , HWANG, Ingyu , MOON, Surk, Sik , KWON, Yong, Kook , AHN, Jung, Ah , LEE, Eun, Sook
IPC: A61K31/35
CPC classification number: A61K31/7048 , A23L2/52 , A23L33/105 , A61K31/352
Abstract: A pharmaceutical composition for inhibiting the activity of 3-hydroxy-3-methylglutaryl CoA(HMG-CoA) reductase in mammals comprises an effective amount of naringin or naringenin as an active ingredient together with a pharmaceutically acceptable carrier, and a food or beverage composition for inhibiting the 3-hydroxy-3-methylglutaryl CoA(HMG-CoA) reductase activity in mammals comprises an effective amount of naringin or naringenin.
Abstract translation: 用于抑制哺乳动物中3-羟基-3-甲基戊二酰CoA（HMG-CoA）还原酶的活性的药物组合物包含有效量的作为活性成分的柚皮苷或柚皮苷与药学上可接受的载体，以及用于 抑制哺乳动物中的3-羟基-3-甲基戊二酰CoA（HMG-CoA）还原酶活性包括有效量的柚皮苷或柚皮素。
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4.发明公开NOVEL $i(SERRATIA MARCESCENS) STRAIN, PRODIGIOSIN AND THE USE OF THE SAME AS AN IMMUNOSUPPRESSIVE 有权新粘质沙雷氏菌灵菌红素STEM及其作为免疫抑制剂使用
公开(公告)号：EP1017840A1
公开(公告)日：2000-07-12
申请号：EP98944328.8
申请日：1998-09-19
Applicant: Korea Institute of Science and Technology
Inventor： KIM, Hwan, Mook , KIM, Young, Kook , HAN, Sang, Bae,16/1, 204-8, Sajik-dong , YOO, Sung, Rak
CPC classification number: C12R1/43 , C12P17/165
Abstract: There are disclosed a novel microorganism Serratia marcescens strain and a prodigiosin isolated from the microorganism. The prodigiosin is useful as an immunosuppressive in various fields, including the treatment of the diseases requiring immunosuppression and the basic research for the diseases, the transplantation of the organs or tissues, and the immune cells.
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5.发明授权NOVEL $i(SERRATIA MARCESCENS) STRAIN, PRODIGIOSIN AND THE USE OF THE SAME AS AN IMMUNOSUPPRESSIVE 有权新粘质沙雷氏菌灵菌红素STEM及其作为免疫抑制剂使用
公开(公告)号：EP1017840B1
公开(公告)日：2006-04-05
申请号：EP98944328.8
申请日：1998-09-19
Inventor： KIM, Hwan, Mook , KIM, Young, Kook , HAN, Sang, Bae, 16/1, 204-8, Sajik-dong , YOO, Sung, Rak
CPC classification number: C12R1/43 , C12P17/165
Abstract: There are disclosed a novel microorganism Serratia marcescens strain and a prodigiosin isolated from the microorganism. The prodigiosin is useful as an immunosuppressive in various fields, including the treatment of the diseases requiring immunosuppression and the basic research for the diseases, the transplantation of the organs or tissues, and the immune cells.
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