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公开(公告)号：WO2012040403A1
公开(公告)日：2012-03-29
申请号：PCT/US2011/052667
申请日：2011-09-21
Applicant: LIFE TECHNOLOGIES CORPORATION , GREEN, Robert , WANG, Dennis , MULERO, Julio , LAGACE, Robert
Inventor： GREEN, Robert , WANG, Dennis , MULERO, Julio , LAGACE, Robert
IPC: C12Q1/68
CPC classification number: C12Q1/6827 , C12Q1/686 , C12Q1/6888 , C12Q2537/143 , C12Q2600/156
Abstract: [ Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.
Abstract translation: 公开了使用高度复杂的序列位点的人类鉴定的引物组合物，方法和试剂盒，SE33（ACTBP2）在单次和多重PCR反应中。 另外，所公开的是在SE33基因座内的三个新发现的单核苷酸多态性（SNP），其可以引起不一致，被视为移动性偏移或等位基因缺失。 还公开了可用于人类鉴定的试剂盒。
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公开(公告)号：WO2011020075A2
公开(公告)日：2011-02-17
申请号：PCT/US2010/045544
申请日：2010-08-13
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： MULERO, Julio , GREEN, Robert , LAGACE, Robert , HENNESSY, Lori
IPC: C12Q1/68
CPC classification number: C07H21/04 , C12Q1/6879 , C12Q2600/156
Abstract: Disclosed are methods for gender determination in the intron 1 region of the amelogenin locus and a newly discovered single nucleotide polymorphism (SNP) within the X chromosome of the amelogenin locus which can cause allelic dropout. Also disclosed are kits useful in gender determination.
Abstract translation: 本发明公开了一种用于性别测定的方法，该方法用于在羊角蛋白素基因座的内含子1区域和新发现的单核苷酸多态性（SNP），其可以引起等位基因缺失。 还公开了可用于性别测定的试剂盒。
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公开(公告)号：WO2011066467A2
公开(公告)日：2011-06-03
申请号：PCT/US2010/058111
申请日：2010-11-24
Applicant: LIFE TECHNOLOGIES CORPORATION , GREEN, Robert , MULERO, Julio , HENNESSY, Lori , LAGACE, Robert , CHANG, Chien-Wei
Inventor： GREEN, Robert , MULERO, Julio , HENNESSY, Lori , LAGACE, Robert , CHANG, Chien-Wei
CPC classification number: C12Q1/6876 , C12Q2600/156 , C12Q2600/166
Abstract: Disclosed are rare short tandem repeat (STR) alleles within the D10S1248 and D12S391 loci in humans. Provided are representative allelic ladders for each locus, methods and assays using these alleles and kits containing allelic ladders comprising these alleles for accurate genotyping and identification of a wide range of individuals.
Abstract translation: 公开了人类D10S1248和D12S391基因座中罕见的短串联重复（STR）等位基因。 提供了每个位点的代表性等位基因梯度，使用这些等位基因的方法和测定法，以及含有包含这些等位基因的等位基因梯的试剂盒，用于准确的基因分型和鉴定广泛的个体。
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公开(公告)号：EP2504433A2
公开(公告)日：2012-10-03
申请号：EP10833985.4
申请日：2010-11-24
Applicant: Life Technologies Corporation
Inventor： GREEN, Robert , MULERO, Julio , HENNESSY, Lori , LAGACE, Robert , CHANG, Chien-Wei
CPC classification number: C12Q1/6876 , C12Q2600/156 , C12Q2600/166
Abstract: Disclosed are rare short tandem repeat (STR) alleles within the D10S1248 and D12S391 loci in humans. Provided are representative allelic ladders for each locus, methods and assays using these alleles and kits containing allelic ladders comprising these alleles for accurate genotyping and identification of a wide range of individuals.
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Patent Agency Ranking
公开(公告)号：EP2619322B1
公开(公告)日：2015-06-03
申请号：EP11767107.3
申请日：2011-09-21
Applicant: Life Technologies Corporation
Inventor： GREEN, Robert , WANG, Dennis , MULERO, Julio , LAGACE, Robert
IPC: C12Q1/68
CPC classification number: C12Q1/6827 , C12Q1/686 , C12Q1/6888 , C12Q2537/143 , C12Q2600/156
Abstract: Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.
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公开(公告)号：EP2504433B1
公开(公告)日：2014-10-29
申请号：EP10833985.4
申请日：2010-11-24
Applicant: Life Technologies Corporation
Inventor： GREEN, Robert , MULERO, Julio , HENNESSY, Lori , LAGACE, Robert , CHANG, Chien-Wei
CPC classification number: C12Q1/6876 , C12Q2600/156 , C12Q2600/166
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公开(公告)号：EP2464754B1
公开(公告)日：2014-03-12
申请号：EP10808855.0
申请日：2010-08-13
Applicant: Life Technologies Corporation
Inventor： MULERO, Julio , GREEN, Robert , LAGACE, Robert , HENNESSY, Lori
CPC classification number: C07H21/04 , C12Q1/6879 , C12Q2600/156
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公开(公告)号：EP2464754A2
公开(公告)日：2012-06-20
申请号：EP10808855.0
申请日：2010-08-13
Applicant: Life Technologies Corporation
Inventor： MULERO, Julio , GREEN, Robert , LAGACE, Robert , HENNESSY, Lori
CPC classification number: C07H21/04 , C12Q1/6879 , C12Q2600/156
Abstract: Disclosed are methods for gender determination in the intron 1 region of the amelogenin locus and a newly discovered single nucleotide polymorphism (SNP) within the X chromosome of the amelogenin locus which can cause allelic dropout. Also disclosed are kits useful in gender determination.
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公开(公告)号：EP2619322A1
公开(公告)日：2013-07-31
申请号：EP11767107.3
申请日：2011-09-21
Applicant: Life Technologies Corporation
Inventor： GREEN, Robert , WANG, Dennis , MULERO, Julio , LAGACE, Robert
IPC: C12Q1/68
CPC classification number: C12Q1/6827 , C12Q1/686 , C12Q1/6888 , C12Q2537/143 , C12Q2600/156
Abstract: Disclosed are primer set compositions, methods and kits for human identification using the highly complex sequence locus, SE33 (ACTBP2) in single and multiplex PCR reactions. Additionally, disclosed are three newly discovered single nucleotide polymorphisms (SNPs) within the SE33 locus that can cause discordance seen as mobility shift or allelic dropout. Also disclosed are kits useful in human identification.
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