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公开(公告)号：WO2022155588A2
公开(公告)日：2022-07-21
申请号：PCT/US2022/012755
申请日：2022-01-18
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： SHANNON, Mark , ELDER, Noah , RAMAMOORTHI, Kalpith , LA, Jason , BLANCHARD, Daniel
IPC: C12Q1/6806
Abstract: Disclosed are compositions, assays, methods, diagnostic methods, kits and diagnostic kits for the detection of target nucleic acids, including those from microbes and/or from infectious agents such as SARS-CoV-2 and other viruses. Embodiments described herein are designed to enable processing and analysis of the sample to detect target nucleic acids within the sample without requiring extraction and/or isolation of nucleic acid from the sample prior to subsequent processing steps. Samples analyzed can thus be "crude" biological samples that do not require pre-processing prior to placement in the workflow.
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2.发明申请COMPOSITIONS, METHODS, AND KITS FOR SYNTHESIS AND DETECTION OF NUCLEIC ACIDS 审中-公开合成和检测核酸的组合物，方法和试剂盒
公开(公告)号：WO2017177025A1
公开(公告)日：2017-10-12
申请号：PCT/US2017/026386
申请日：2017-04-06
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： LE, Ferrier , RAMAMOORTHI, Kalpith , WILDE, Joyce , FANTIN, Nicole , LANG, Jordan , DUPONT, David , STEVENS, Junko
IPC: C12Q1/68
Abstract: Compositions, methods, and kits for synthesizing, detecting, and/or quantifying nucleic acids are provided herein. Embodiments comprise a nucleic acid amplification composition comprising a thermostable DNA polymerase and agents which improve nucleic acid synthesis, amplification, detection, and/or quantification of nucleic acid targets in a crude extract or crude lysate sample.
Abstract translation: 本文提供了用于合成，检测和/或定量核酸的组合物，方法和试剂盒。 实施方案包含核酸扩增组合物，其包含热稳定DNA聚合酶和改善粗提取物或粗溶解物样品中的核酸靶标的核酸合成，扩增，检测和/或定量的试剂。
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公开(公告)号：WO2017177025A9
公开(公告)日：2017-10-12
申请号：PCT/US2017/026386
申请日：2017-04-06
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： LE, Ferrier , RAMAMOORTHI, Kalpith , WILDE, Joyce , FANTIN, Nicole , LANG, Jordan , DUPONT, David , STEVENS, Junko
IPC: C12Q1/68
Abstract: Compositions, methods, and kits for synthesizing, detecting, and/or quantifying nucleic acids are provided herein. Embodiments comprise a nucleic acid amplification composition comprising a thermostable DNA polymerase and agents which improve nucleic acid synthesis, amplification, detection, and/or quantification of nucleic acid targets in a crude extract or crude lysate sample.
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Patent Agency Ranking
公开(公告)号：WO2023039525A1
公开(公告)日：2023-03-16
申请号：PCT/US2022/076204
申请日：2022-09-09
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： RAMAMOORTHI, Kalpith , ELDER, Noah
IPC: C12Q1/6806 , C12Q1/6832 , C12Q1/686
Abstract: Disclosed are master mix compositions, kits, and related methods for use in amplifying a target nucleic acid. A master mix composition may be formulated to enable effective reaction mixture loading onto a dPCR plate, provide high proportion of valid/readable partitions, enable identification and distinguishing between amplified and unamplified partitions, enable detection of low abundance targets amidst high background levels of non-target nucleic acids and/or amidst inhibiting agents, and/or enable effective detection of low frequency mutant alleles.
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5.发明申请
公开(公告)号：WO2022203748A1
公开(公告)日：2022-09-29
申请号：PCT/US2022/012805
申请日：2022-01-18
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： WANG, Chunling , SHANG, Yulei , PABBATI, Namrata , LI, Kelly , PAGANI, Ioanna , BRZOSKA, Pius , TANNER, Michael , SHANNON, Mark , ELDER, Noah , RAMAMOORTHI, Kalpith , LA, Jason , BLANCHARD, Daniel , LI, Jisheng
IPC: C12Q1/6888 , C12Q2537/143
Abstract: Disclosed are compositions, assays, methods, diagnostic methods, kits and diagnostic kits for the specific and differential detection of SARS-CoV-2, including SARS-CoV-2 variants, or other coronaviruses from samples including veterinary samples, clinical samples, food samples, forensic sample, an environmental sample (e.g., soil, dirt, garbage, sewage, air, or water), including food processing and manufacturing surfaces, or a biological sample.
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6.发明公开
公开(公告)号：EP4314350A1
公开(公告)日：2024-02-07
申请号：EP22703496.4
申请日：2022-01-18
Applicant: Life Technologies Corporation
Inventor： WANG, Chunling , SHANG, Yulei , PABBATI, Namrata , LI, Kelly , PAGANI, Ioanna , BRZOSKA, Pius , TANNER, Michael , SHANNON, Mark , ELDER, Noah , RAMAMOORTHI, Kalpith , LA, Jason , BLANCHARD, Daniel , LI, Jisheng
IPC: C12Q1/6888
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公开(公告)号：EP4278002A2
公开(公告)日：2023-11-22
申请号：EP22703196.0
申请日：2022-01-18
Applicant: Life Technologies Corporation
Inventor： SHANNON, Mark , ELDER, Noah , RAMAMOORTHI, Kalpith , LA, Jason , BLANCHARD, Daniel
IPC: C12Q1/6806
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公开(公告)号：EP3440221A1
公开(公告)日：2019-02-13
申请号：EP17718305.0
申请日：2017-04-06
Applicant: Life Technologies Corporation
Inventor： LE, Ferrier , RAMAMOORTHI, Kalpith , WILDE, Joyce , FANTIN, Nicole , LANG, Jordan , DUPONT, David , STEVENS, Junko
IPC: C12Q1/68
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