PROTEIN DETECTION USING FET
    1.
    发明申请
    PROTEIN DETECTION USING FET 审中-公开
    蛋白质检测使用FET

    公开(公告)号:WO2014004587A2

    公开(公告)日:2014-01-03

    申请号:PCT/US2013/047726

    申请日:2013-06-25

    Abstract: Accordingly, in some embodiments methods for detecting an analyte or analytes in one or more sample(s) are provided. The methods encompass providing a solid support with an addressable marker and an associated ligand, contacting the solid substrate to a sample, thereby forming a contacted solid support, associating the contacted solid support with a FET array and detecting the electrical properties of the FET array and thereby detecting an analyte or analytes in one or more samples. In other embodiments, the sample encompasses a second addressable marker.

    Abstract translation: 因此,在一些实施例中,提供了用于检测一个或多个样品中的分析物或分析物的方法。 所述方法包括提供具有可寻址标记和相关配体的固体支持物,将固体基质接触样品,从而形成接触的固体支持物,将接触的固体支持物与FET阵列相关联,并检测FET阵列的电特性, 从而检测一个或多个样品中的分析物或分析物。 在其他实施例中,样本包含第二可寻址标记。

    SEMI-INVASIVE METHOD FOR CHARACTERIZING LUNG INJURY
    2.
    发明申请
    SEMI-INVASIVE METHOD FOR CHARACTERIZING LUNG INJURY 审中-公开
    用于表征肺损伤的半导体方法

    公开(公告)号:WO2011112749A2

    公开(公告)日:2011-09-15

    申请号:PCT/US2011/027790

    申请日:2011-03-09

    Abstract: Described and disclosed are methods for determining, predicting, diagnosing, treating, and monitoring lung diseases, including bronchiolitis obliterans syndrome and acute cellular rejection in a lung transplant recipient by measuring chemokine levels in bronchoalveolar lavage (BAL) samples. The chemokine CXCL10 is measured in combination with at least one analyte selected from the group consisting of IL1RA, CXCL11, MCP-1, CXCL9, RANTES, IL-13, IL-17, IL-22, fractalkine, and eotaxin; and/or biomarkers. The present teachings also relate to methods, treatment decisions and kits for detecting and monitoring onset of lung transplant rejection in advance of clinically recognized symptoms.

    Abstract translation: 描述和公开了通过测量支气管肺泡灌洗(BAL)样品中的趋化因子水平来确定,预测,诊断,治疗和监测肺部疾病的方法,包括闭塞性细支气管炎综合征和肺移植受体中的急性细胞排斥反应。 与至少一种选自IL1RA,CXCL11,MCP-1,CXCL9,RANTES,IL-13,IL-17,IL-22,fractalkine和嗜酸细胞活化趋化因子的分析物组合测量趋化因子CXCL10; 和/或生物标志物。 本教导还涉及在临床认可的症状之前检测和监测肺移植排斥发作的方法,治疗决定和试剂盒。

    PROTEIN DETECTION USING FET
    3.
    发明公开
    PROTEIN DETECTION USING FET 有权
    蛋白酶MIT FET

    公开(公告)号:EP2864786A2

    公开(公告)日:2015-04-29

    申请号:EP13737907.9

    申请日:2013-06-25

    Abstract: Accordingly, in some embodiments methods for detecting an analyte or analytes in one or more sample(s) are provided. The methods encompass providing a solid support with an addressable marker and an associated ligand, contacting the solid substrate to a sample, thereby forming a contacted solid support, associating the contacted solid support with a FET array and detecting the electrical properties of the FET array and thereby detecting an analyte or analytes in one or more samples. In other embodiments, the sample encompasses a second addressable marker.

    Abstract translation: 因此,在一些实施方案中,提供了用于检测一个或多个样品中的分析物或分析物的方法。 所述方法包括提供具有可寻址标记和相关配体的固体支持物,使固体基质与样品接触,从而形成接触的固体支持物,将接触的固体支持物与FET阵列相关联并检测FET阵列的电特性, 从而检测一个或多个样品中的分析物或分析物。 在其他实施例中,样本包含第二可寻址标记。

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