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公开(公告)号:US6270844B2
公开(公告)日:2001-08-07
申请号:US74077900
申请日:2000-12-19
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , ROMACK TIMOTHY J , DEYOUNG JAMES P
IPC: B05D1/18 , C23C26/00 , C23C30/00 , D06M15/277 , D06M15/643 , D06M23/10 , B05D1/00
CPC classification number: D06M15/643 , B05D1/18 , B05D2401/90 , C23C26/00 , C23C30/00 , D06M15/277 , D06M23/10 , D06M23/105 , D06M2101/06 , D06M2101/08 , D06M2101/12 , D06M2101/32 , D06M2101/34 , D06M2200/12
Abstract: A method of treating a substrate comprises contacting a surface of said substrate, with a pressurized fluid comprising carbon dioxide and a surface treatment component, the surface treatment component being entrained in the pressurized fluid and contacting the surface so that the surface treatment component lowers the surface tension of the surface of the substrate and treats the substrate. The contacting step is preferably carried out by immersion, the fluid is preferably a liquid or supercritical fluid, the substrate is preferably a metal or fabric substrate, and the surface treatment component is preferably a fluoroacrylate polymer.
Abstract translation: 处理基材的方法包括使所述基材的表面与包含二氧化碳和表面处理组分的加压流体接触,所述表面处理组分被夹带在加压流体中并与表面接触,使得表面处理组分降低表面 衬底表面的张力并处理衬底。 接触步骤优选通过浸渍进行,流体优选为液体或超临界流体,基底优选为金属或织物基底,并且表面处理组分优选为氟代丙烯酸酯聚合物。
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公开(公告)号:AU2017210510B2
公开(公告)日:2019-09-19
申请号:AU2017210510
申请日:2017-08-01
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR CHARLES DOUGLAS , FAGAN MEAGAN M
IPC: A61M31/00
Abstract: Abstract A medical device that releases a pharmaceutical agent to a target site is disclosed. The medical device includes a balloon, and a coating on at least a portion of the balloon. Each particle of the particles of the pharmaceutical agent is at least partially encapsulated in a polymer layer. The method includes the steps of providing a device including a balloon, and a coating on at least a portion of the balloon, the coating including particles of a pharmaceutical agent, and each particle of the pharmaceutical agent is at least partially encapsulated in a polymer layer; positioning the device to allow the balloon to reach the target site; and inflating the balloon of the device.
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公开(公告)号:AU2017219090A1
公开(公告)日:2018-04-12
申请号:AU2017219090
申请日:2017-08-25
Applicant: MICELL TECHNOLOGIES INC
Inventor: KIORPES TIMOTHY CHARLES , MCCLAIN JAMES B
Abstract: A drug-eluting product is disclosed comprising an at least partially bioabsorbable element and an active pharmaceutical agent having a morphology, a solubility, and an average particle size which are selected so that the active pharmaceutical agent continues to dissolve during the biodegradation of the bioabsorbable element. The morphology is a crystalline, semi-crystalline or amorphous morphology, the solubility is less than 100 ptg/ml and the average particle size is grater that about 100 nm.
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公开(公告)号:AU2017210510A1
公开(公告)日:2017-08-17
申请号:AU2017210510
申请日:2017-08-01
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR CHARLES DOUGLAS , FAGAN MEAGAN M
IPC: A61M31/00
Abstract: Abstract A medical device that releases a pharmaceutical agent to a target site is disclosed. The medical device includes a balloon, and a coating on at least a portion of the balloon. Each particle of the particles of the pharmaceutical agent is at least partially encapsulated in a polymer layer. The method includes the steps of providing a device including a balloon, and a coating on at least a portion of the balloon, the coating including particles of a pharmaceutical agent, and each particle of the pharmaceutical agent is at least partially encapsulated in a polymer layer; positioning the device to allow the balloon to reach the target site; and inflating the balloon of the device.
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公开(公告)号:AU2012326010B2
公开(公告)日:2017-05-11
申请号:AU2012326010
申请日:2012-10-18
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR CHARLES DOUGLAS , FAGAN MEGAN M
IPC: A61M31/00
Abstract: A medical device that releases a pharmaceutical agent to a target site is disclosed. The medical device includes a balloon, and a coating on at least a portion of the balloon. Each particle of the particles of the pharmaceutical agent is at least partially encapsulated in a polymer layer. The method includes the steps of providing a device including a balloon, and a coating on at least a portion of the balloon, the coating including particles of a pharmaceutical agent, and each particle of the pharmaceutical agent is at least partially encapsulated in a polymer layer; positioning the device to allow the balloon to reach the target site; and inflating the balloon of the device.
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公开(公告)号:ZA201007405B
公开(公告)日:2017-04-26
申请号:ZA201007405
申请日:2010-10-15
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR DOUGLAS
Abstract: Provided herein is a device comprising: a. stent; b. a plurality of layers on said stent framework to form said device; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.
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公开(公告)号:CA2613280C
公开(公告)日:2016-05-10
申请号:CA2613280
申请日:2006-06-21
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , DEYOUNG JAMES P
Abstract: A method of forming a drug/polymer composite material is carried out by combining a drug material with a polymer material under pressure in the presence of a densified gas solvent (e.g., carbon dioxide) to form the drug/polymer composite material. Drug/polymer composite materials and shaped articles (e.g., subcutaneous drug depots) which may be produced by a process are also described, along with methods of use thereof.
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公开(公告)号:AU2014265460A1
公开(公告)日:2015-12-17
申请号:AU2014265460
申请日:2014-05-15
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B
Abstract: A bioabsorbable biomedical implant is disclosed. The implant includes a tubular scaffold comprising a plurality of interconnected polymer struts. The interconnected polymer struts defines a plurality of deformable cells. The polymer struts have an average thickness of no more than 150 μm. Methods for making the bioabsorbable biomedical implant, including the methods for making the fiber-reinforced polymer composite materials for the tubular scaffold, are also disclosed.
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公开(公告)号:CA2912387A1
公开(公告)日:2014-11-20
申请号:CA2912387
申请日:2014-05-15
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B
Abstract: A bioabsorbable biomedical implant is disclosed. The implant includes a tubular scaffold comprising a plurality of interconnected polymer struts. The interconnected polymer struts defines a plurality of deformable cells. The polymer struts have an average thickness of no more than 150 µm. Methods for making the bioabsorbable biomedical implant, including the methods for making the fiber-reinforced polymer composite materials for the tubular scaffold, are also disclosed.
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公开(公告)号:SG192524A1
公开(公告)日:2013-08-30
申请号:SG2013054127
申请日:2009-04-17
Applicant: MICELL TECHNOLOGIES INC
Inventor: MCCLAIN JAMES B , TAYLOR DOUGLAS
Abstract: Provided herein is a device comprising: a. stent; b. a plurality of layers on said stent framework to form said device; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.FIGURE 22
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