公开(公告)号：AT546522T

公开(公告)日：2012-03-15

申请号：AT07754529

申请日：2007-03-29

Applicant: PACIFIC BIOSCIENCES CALIFORNIA

Inventor： RANK DAVID ,  WEGENER JEFFERY ,  KORLACH JONAS ,  ROITMAN DANIEL ,  XU YUE ,  LYLE JOHN ,  TURNER STEPHEN ,  PELUSO PAUL ,  OTTO GEOFF ,  CICERO RONALD

IPC: C12N11/00 ,  C40B40/04

Abstract: Methods of producing substrates having selected active chemical regions by employing elements of the substrates in assisting the localization of active chemical groups in desired regions of the substrate. The methods may include optical, chemical and/or mechanical processes for the deposition, removal, activation and/or deactivation of chemical groups in selected regions of the substrate to provide selective active regions of the substrate.

公开(公告)号：WO2011031313A2

公开(公告)日：2011-03-17

申请号：PCT/US2010002458

申请日：2010-09-08

Applicant: PACIFIC BIOSCIENCES CALIFORNIA ,  GREY JEREMY ,  CICERO RONALD ,  GROT ANNETTE ,  POPOVICH NATASHA ,  DUDEK STEPHEN

Inventor： GREY JEREMY ,  CICERO RONALD ,  GROT ANNETTE ,  POPOVICH NATASHA ,  DUDEK STEPHEN

IPC: G02B6/122 ,  G02B6/28

CPC classification number: G02B6/107 ,  C23F1/00 ,  C23F17/00 ,  C25D11/022 ,  C25D11/04 ,  G01N21/6452 ,  G01N21/7743 ,  G02B6/10 ,  G02B6/136

Abstract: The application relates to improved optical containment structures, methods of manufacture and use, and systems for employing same. The optical containment structures generally comprise zero-mode waveguide structures having non-reflective walls. The non-reflective walls allow the preparation of optical containment regions in which the optical containment dimensions can be decoupled from the solution containment dimensions. The application also relates to methods for producing islands of functionality within nanoscale apertures.

Abstract translation: 本申请涉及改进的光学容纳结构，制造和使用方法以及使用它们的系统。 光学容纳结构通常包括具有非反射壁的零模式波导结构。 非反射壁允许制备光学容纳区域，其中光学容纳尺寸可以与溶液容纳尺寸分离。 该应用还涉及在纳米尺度孔内产生功能岛的方法。